Effect of Linseed Oil Ingestion on Plasma Lipid Fatty Acid Composition and Platelet Aggregability in Healthy Volunteers.
Effect of Linseed Oil Ingestion on Plasma Lipid Fatty Acid Composition and Platelet Aggregability in Healthy Volunteers.
Year: 1984
Authors: Budowski, P., Trostler, N., Lupo, M., Vaisman, N., Eldor, A.
Publication Name: Nutr. Res.
Publication Details: Volume 4, Pages 343-346.
Abstract:
Eight healthy volunteers ingested 60 ml linseed oil over a period of six weeks. Ieosapentaenoic acid increased in plasma triglycerides (TG), phospholipids (PL) and cholesteryl esters (CE) but did not exceed mean values of 2%. alpha-Linolenic acid rose markedly in TG, linoleic acid decreased in TG and CE, and arachidonic acid decreased in PL and CE. Two additional subjects on a similar regimen underwent blood platelet aggregability tests by the collagen threshold procedure. In both cases a striking decrease in platelet sensitivity to collagen was observed. The results show that linseed oil affects the polyunsaturated fatty acid profile of plasma liplds and suggest a possible alteration of platelet aggregability. Author's Abstract.
