Feeding enriched omega-3 fatty acid beef to rats increases omega-3 fatty acid content of heart and liver membranes and decreases serum vascular cell adhesion molecule-1 and cholesterol levels.
Feeding enriched omega-3 fatty acid beef to rats increases omega-3 fatty acid content of heart and liver membranes and decreases serum vascular cell adhesion molecule-1 and cholesterol levels.
Year: 2007
Authors: Medeiros, D.M., Hampton, M., Kurtzer, K., Parelman, M., Al-Tamimi, E., Drouillard, J.S.
Publication Name: Nutr. Res.
Publication Details: Volume 27, Pages 295-9.
Abstract:
Dietary intake of the long-chain omega-3 fatty acids prevents the development of heart disease. In
this study, we evaluated whether feeding beef from cattle fed an omega-3 fatty acid–enriched diet to
rats had health benefits. Cattle raised on a 10% flaxseed diet have high amounts of a-linolenic acid in
their muscle tissue when compared to cattle fed a control diet of corn. Twenty, weanling, Sprague-
Dawley rats were fed one of two diets (n = 10 in each group), one diet containing fat from beef of
cattle fed 10% flaxseed and the other beef from cattle fed a conventional corn ration. The diets
contained 10% fat from the cooked beef using a modification of the American Institute of Nutrition
diet formulated in 1976 diet for a 5-week period. There was a statistically significant increase in the
amount of membrane docosahexaenoic acid in the livers of the rats on the diet of beef from cattle fed
flaxseed and a statistically significant increase in the amount of membrane arachidonic acid in the
hearts of the controls. There were also strong, positive trends for the increases in the amounts of
membrane docosahexaenoic acid in the hearts and membrane linoleic acid in the livers of the rats on
the diet of beef from cattle fed flaxseed when compared with controls. Serum cholesterol and
vascular cell adhesion molecule-1 levels were decreased in rats fed the beef from cattle fed flaxseed.
These findings suggest that agriculture practice of feeding a high omega-3 fatty acid diet to cattle can
produce positive health benefits to the consumer. Author's Abstract.
this study, we evaluated whether feeding beef from cattle fed an omega-3 fatty acid–enriched diet to
rats had health benefits. Cattle raised on a 10% flaxseed diet have high amounts of a-linolenic acid in
their muscle tissue when compared to cattle fed a control diet of corn. Twenty, weanling, Sprague-
Dawley rats were fed one of two diets (n = 10 in each group), one diet containing fat from beef of
cattle fed 10% flaxseed and the other beef from cattle fed a conventional corn ration. The diets
contained 10% fat from the cooked beef using a modification of the American Institute of Nutrition
diet formulated in 1976 diet for a 5-week period. There was a statistically significant increase in the
amount of membrane docosahexaenoic acid in the livers of the rats on the diet of beef from cattle fed
flaxseed and a statistically significant increase in the amount of membrane arachidonic acid in the
hearts of the controls. There were also strong, positive trends for the increases in the amounts of
membrane docosahexaenoic acid in the hearts and membrane linoleic acid in the livers of the rats on
the diet of beef from cattle fed flaxseed when compared with controls. Serum cholesterol and
vascular cell adhesion molecule-1 levels were decreased in rats fed the beef from cattle fed flaxseed.
These findings suggest that agriculture practice of feeding a high omega-3 fatty acid diet to cattle can
produce positive health benefits to the consumer. Author's Abstract.
