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2014

Flaxseed fed pork: n3 fatty acid enrichment and contribution to dietary recommendations

Authors: Turner, T.D. Mapive, C. Aalhus, J.L. Beaulieu, A.D. Patience, J.F. Zilstra, R.T. Dugan, M.E.R.

Publication Name: Meat Sci.

Effect of phenolic compound removal on rheological, thermal and physicochemical properties of soybean and flaxseed proteins

Authors: Aludatt, M.H. Rababah, T. Alli, I.

Publication Name: Food Chem.

Enrichment of wheat chips with omega 3 fatty acid by flaxseed addition: Textural and some physicochemical properties

Authors: Yuksel, F. Karaman, S. Kayacier, A.

Publication Name: Food Chem.

Habitual Diets Rich in Dark-Green Vegetables Are Associated with an Increased Response to n3 Fatty Acid Supplementation in Americans of African Ancestry

Authors: O'Sullivan, A. Armstrong, P. Schuster, G.U. Pedersen, T.L. Allayee, H. Stephensen, C.B. Newman, J.W.

Publication Name: J. Nutr.

Effect of Cyclolinopeptides on the Oxidative Stability of Flaxseed Oil

Authors: Sharav, O. Shim, Y.Y. Okinyo-Owiti, D.P Sammynaiken, R. Reaney, M.J.T.

Publication Name: J. Agric. Food Chem.

Phenolic Compounds in Flaxseed: a Review of Their Properties and Analytical Methods. An Overview of the Last Decade

Authors: Herchi, W. Arraez-Roman, D. Trabelsi, H. Bouali, I. Boukhchina, S. Kallel, H. Segura-Carretero, A. Fernandez-Gutierrez, A.

Publication Name: J. Oleo Sci

Identification, Characterization, and Quantification of an Antipyridoxine Factor from Flaxseed Using Ultrahigh-Performance Liquid Chromatography−Mass Spectrometry

Authors: Mayengbam, S. Yang, H. Barthet, V. Aliani, M. House, J.D.

Publication Name: J. Agric. Food Chem

Bioavailability and Potential Uses of Vegetarian Sources of Omega-3 Fatty Acids: A Review of the Literature

Authors: Lane, K. Derbyshire, E. Li, W. Brennan, C.

Publication Name: Crit. Rev. Food Sci. Nutr.

Position of the Academy of Nutrition and Dietetics: Dietary Fatty Acids for Healthy Adults

Authors: Rasmussen, H.

Publication Name: J Acad Nutr Diet

Permeability and Conjugative Metabolism of Flaxseed Lignans by Caco 2 Human Intestinal Cells

Authors: Mukker, J.T. Michel, D. Muir, A.D. Krol, E.S. Alcom, J.

Publication Name: J.Nat.Prod

New Flaxseed Orbitides: Detection, Sequencing and 15N Incorporation

Authors: Okinyo-Owiti, D.P. Young, L. Burnett, P-G. G. Reaney, M.J.T.

Publication Name: Biopolymers

Adherence in a 1 to year whole foods eating pattern intervention with healthy postmenopausal women

Authors: Peters, N.C. Contento, I.R. Kronenberg, F. Coleton, M.

Publication Name: Public Health Nutr.

Whole to body retention of alpha linolenic acid and its apparent conversion to other n3 PUFA in growing pigs are reduced with the duration of feeding alpha linolenic acid

Authors:

Publication Name: Br J Nutr.

Metabolism of secoisolariciresinol to diglycoside the dietary precursor to the intestinally derived lignin enterolactone in humans

Authors: Setchell, K.D.R. Brown, N.M.Zimmer to Nechemias, L. Wolfe, B. Jha, P. Heubib, J.E.

Publication Name: Food Func.

n3 PUFAs improved endothelial function and arterial stiffness with a parallel anti inflammatory effect in adults with metabolic syndrome

Authors: Tousoulis, D. Plastiras, A. Siasos, G. Oikonomou, E. Verveniotis, A. Kokkou, E. Maniatis, K. Gouliopoulos, N. Miliou, A. et al

Publication Name: Atherosclerosis

Preventitive Effects of lignan Extract from Flax Hulls On Experimentally Induced Benign Prostate Hyperplasia

Authors: Bisson, J.F. Hidalgo, S. Simmons, R. Verbruggen, M.

Publication Name: J Med Food

Whole body synthesis rates of docosahexaenoic acid (DHA) from α to linolenic acid are greater than brain DHA accretion and uptake rates in adult rats.

Authors: Domenichiello, A.F. Chen, C.T. Trepanier, M.O. Stavro, P.M. Bazinet, R.P.

Publication Name: J Lipid Res.

Effects of Dietary Milled Seed Mixture on Fatty Acid Status and Inflammatory Markers in Patients on Hemodialysis

Authors: Perunicic-Pekovic, G. Rasic-Milutinovic, Z. Takic, M. Popovic, T. Arsic, A. Glibetic, M.

Publication Name: Sci World Jour.

Anti diabetic and antihypertensive activities of two flaxseed protein hydrolysate fractions revealed following their simultaneous separation by electrodialysis with ultrafiltration membranes

Authors: Doyen, A. Udenigwe, C.C. Mitchell, P.L. Marette, A. Aluko, R.E. Bazinet, L.

Publication Name: Food Chem.

A combination of flaxseed oil and astaxanthin alleviates atherosclerosis risk factors in high fat diet fed rats.

Authors: Xu, J. Gao, H. Zhang, L. Chen, C. Yang, W. Deng, Q. Huang, Q. Huang, F.

Publication Name: Lipids in Health and Disease

A Pilot Study Comparing the Effect of Flaxseed, Aromatase Inhibitor, and the Combination on Breast Tumor Biomarkers

Authors: McCann, S.E. Edge, S.B. Hicks, D.G. Thompson, L.U. Morrison, C.D. Fetterly, G. Andrews, C. Clark, K.

Publication Name: Nutr. Cancer

Protective effect of dietary flaxseed oil on arsenic-induced nephrotoxicity and oxidative damage in rat kidney

Authors: Rizwan, S. Naqshbandi, A. Farooqui, Z. Khan, A.A. Khan, F.

Publication Name: Food Chem. Toxicol

Blood docosahexaenoic acid and eicosapentaenoic acid in vegans: Associations with age and gender and effects of an algal-derived omega 3 fatty acid supplement

Authors: Sarter, B. Kelsey, K.S. Schwartz, T.A. Harris, W.S.

Publication Name: Clin Nutr.

Flaxseed Consumption Reduces Blood Pressure in Patients with Hypertension by Altering Circulating Oxylipins via an Alpha Linolenic Acid Induced Inhibition of Soluble Epoxide Hydrolase.

Authors: Caliqiuri, S.P. Aukema, H.M. Ravandi, A. Guzman, R. Dibrov, E. Pierce, G.N.

Publication Name: Hypertension

Plasma fatty acid changes following consumption of dietary oils containing n3, n6, and n9 fatty acids at different proportions: preliminary findings of the Canola Oil Multicenter Intervention Trial (COMIT)

Authors: Senanayake, V.K. Pu, S. Jenkins, D.A. Lamarche, B. Kris-Etherton, P.M. West, S.G. Fleming, J.A. Liu, X./McCrea, C.E. et al.

Publication Name: Trials

Plant Extracts and Plant-Derived Compounds: Promising Players in Countermeasure Strategy Against Radiological Exposure: A Review

Authors:

Publication Name: Asian Pac J. Canc. Prev.

Sexually immature male ERE-Luc reporter mice to assess low dose estrogen-like effects of CdCI 2 versus dietary CD

Authors: Ramachandran, B. Rizzi, N. Maggi, A.

Publication Name: Am J Nucl Med Mol Imaging

Effect of Flaxseed Meals and Extracts on Lipid Stability in a Stored Meat Product

Authors: Waszkowiak, K. Rudzinska, M.

Publication Name: J Am Oil Chem Soc

Flaxseed Hull: Chemical Composition and Antioxidant Activity during Development

Authors: Al Hjaili, A.D. Sakouhi, F. Sebei, K. Trabelsi, H. Kallel, H. Boukhchina, S.

Publication Name: J. Oleo Sci.

Effect of omega 3 fatty acid supplementation on cancer incidence non vascular death, and total mortality; a meta analysis of randomized controlled trials

Authors: Zhang, Y.F. Gao, H.F. Hou, A.J. Zhang, Y.H.Z.

Publication Name: BMC Public Health

Fasting Whole Blood Fatty Acid Profile and Risk of Type 2 Diabetes in Adults: A Nested Case Control Study

Authors: Alhazmi, A. Stojanovski, E. Garg, M.L. McEvoy, M.

Publication Name: PLoS One

Historical perspectives on the impact of n3 and n6 nutrients on health

Authors: Lands, B.

Publication Name: Prog Lipid Res

Effects of 1 Year Intervention with a Mediterranean Diet on Plasma Fatty Acid Composition and Metabolic Syndrome in a Population at High Cardiovascular Risk

Authors: Perxachs, J.M. SalaVila, A. Chisaguano, M. Castellote, A.I. Estruch, R. Covas, M.I. Fito, M. et al.

Publication Name: PLoS One

Dietary Zinc Deficiency Affects Blood Linoleic Acid: Dihomo gamma linolenic Acid (LA; DGLA) Ratio; a Sensitive Physiological Marker of Zinc Status in Vivo (Gallus gallus)

Authors: Reed, S. Qin, X. Ran Ressler, R. Brenna, J.T. Glahn, R.P. Tako, E.

Publication Name: Nutrients

Effects of supplementing n 3 fatty acid enriched eggs and walnuts on cardiovascular disease risk markers in healthy free living lacto ovo vegetarians: a randomized crossover, free living intervention study

Authors: Whitmore, B.B. Haddad, E. Sabate, J. Rajaram, S.

Publication Name: Nutr J.

Providing male rats deficient in iron and n3 fatty acids with iron and alpha linolenic acid alone affects brain serotonin and cognition differently from combined provision

Authors: Baumgartner, J. Smuts, C.M. Zimmermann, M.B.

Publication Name: Lipids Health Dis.

U.S. adults are not meeting recommended levels for fish and omega 3 fatty acid intake results of an analysis using observational data from NHANES 2003 2008

Authors: Papanikolaou, Y. Brooks, J. Reider, C. Fulgoni, V.L.

Publication Name: Nutr. J.

Omega 3 Fatty Acid Enriched Chevon (Goat Meat) Lowers Plasma Cholesterol Levels and Alters Gene Expressions in Rats

Authors: Ebrahimi, M. Rajion, A. YongMeng, G. Farjam, A.S.

Publication Name: Biomed Res Int.

Reducing the Dietary Omega 6 Omega 3 Utilizing alpha Linolenic Acid; Not a Sufficient Therapy for Attenuating High Fat Diet Induced Obesity Development Nor Related Detrimental Metabolic and Adipose Tissue Inflammatory Outcomes

Authors: Enos, R.T. Velazquez, K.T. McClellan, J.L. Cranford, T.L. Walla, M.D. Murphy, E.A.

Publication Name: PLoS One

Neuropathological Responses to Chronic NMDA in Rats Are Worsened by Dietary n 3 PUFA Deprivation but Are Not Ameliorated by Fish Oil Supplementation

Authors: Keleshian, V.L. Kellom, M. Kim, H.W. Taha, A.Y. Cheon, Y. Igarashi, M. Rapoport, S.I. Rao, J.S.

Publication Name: PLoS One

Effect of seasonality on the estimated mean value of nutrients and ranking ability of a self administered diet history questionnaire

Authors: Suga, H. Asakura, K. Sasaki, S. Nojima, M. Okubo, H. Hirota, N. Notsu, A. Fukui, M.

Publication Name: Nutr J.

The inverse association between relative abundances of oleic acid and arachidonic acid is related to alpha linolenic acid

Authors: Hostmark, A.T. Haug, A.

Publication Name: Lipids Health Dis

Antiperoxidative properties of oil mixes of high ratio Omega 9 Omega 6 and low ratio Omega 6 Omega 3 after molar extraction in rats

Authors: Melol, R.B. Guimaraesll, S.B. de Barros Silvalll, P.G. OriaIV, R.B. de Souza MeloV, J.U. Leitao, P.R.

Publication Name: Acta Cir Bras

Docosahexaenoic Acid But Not Alpha-Linolenic Acid Ameliorates High Fat Diet Induced Atherosclerosis and Hypertension in APOE-/-Mice via Il-1 Mechanism

Authors: Alfaidi, M. Chamberlain, J. Francis, S.

Publication Name: Heart

Brown adipose but not white adipose accumulate DHA in cultured cells provided with alpha linolenic acid

Authors: Qin, G.

Publication Name: ISSFAL International Congress, Stockholm, Sweden June 28 - July 1

Dietary alpha linolenic acid and long chain n3 PUFA partners in prevention of all cause mortality in individuals at high cardiovascular risk.

Authors: Sala Vila, A.

Publication Name: ISSFAL International Congress, Stockholm, Sweden June 28 - July 1

A low omega 6 polyunsaturated fatty acid (n 6 PUFA) diet increases omega 3 (n 3) long chain PUFA status in plasma phospholipids in humans.

Authors: Wood, K.E.

Publication Name: ISSFAL International Congress, Stockholm, Sweden June 28 - July 1

Amelioration of disease progression and oxylipin abnormalities in pcy mouse kidneys by dietary flax oil demonstrates that alpha linolenic acid can be sufficiently converted to docosahexaenoic acid (DHA) to maintain DHA oxylipins levels

Authors: Aukema, H.M.

Publication Name: ISSFAL International Congress, Stockholm, Sweden June 28 - July 1

Modulation of Adipogenesis by Oxylipins ? Differential Effects on Lipid Droplet Formation and Adipokine Production

Authors: Aukema, H.M.

Publication Name: ISSFAL International Congress, Stockholm, Sweden June 28 - July 1

Is maternal intake of ALA from Flaxseed neuroprotective against neonatal hypoxicischemic brain injury?

Authors: Barros, M.E.

Publication Name: ISSFAL International Congress, Stockholm, Sweden June 28 - July 1

Dairy fat or ALA rich rapeseed diets for dams and mice offspring are similarly protecting against anxiety observed with low ALA palm diet

Authors: Bernadette, A.

Publication Name: ISSFAL International Congress, Stockholm, Sweden June 28 - July 1

Brain DHA restoration in young deficient rat is better with pure or blended dairyfat diets compared to similar ALA content vegetable blends

Authors:

Publication Name: ISSFAL International Congress, Stockholm, Sweden June 28 - July 1

Protective effect of dairy fat on brain DHA levels of young rats born from ALA deficient or ALA rich mothers

Authors: Bernadette, A.

Publication Name: ISSFAL International Congress, Stockholm, Sweden June 28 - July 1

Impact of Denutrition and lipid quality for renutrition on plasma fatty acids and inflammatory markers in old rats

Authors: Bernadette, A.

Publication Name: ISSFAL International Congress, Stockholm, Sweden June 28 - July 1

A novel soluble epoxide hydrolase inhibitor: Flaxseed alters the plasma oxylipin profile and reduces blood pressure in a randomized, double blinded, placebo controlled clinical trial

Authors: Caligiuri, S.P.

Publication Name: ISSFAL International Congress, Stockholm, Sweden June 28 - July 1

Dietary linoleic acid (LA) does not alter renal phospholipid arachidonic acid (ARA) but does significantly alter oxylipins in renal tissue of obese rats

Authors: Caligiuri, S.P.

Publication Name: ISSFAL International Congress, Stockholm, Sweden June 28 - July 1

Conversion of alpha linolenic acid to longer chain n3 fatty acids: competition with linoleic and oleic acids for the delta 6 desaturase

Authors: Choque, B.

Publication Name: ISSFAL International Congress, Stockholm, Sweden June 28 - July 1

Reassessment of the linoleic acid requirement in presence of alpha linolenic acid in the growing rat

Authors: Choque, B.

Publication Name: ISSFAL International Congress, Stockholm, Sweden June 28 - July 1

High fat diets rich in n3 or n6 polyunsaturated fatty acids have distinct effects on lipid profiles and lipid peroxidation in mice selected for either high body weight or leanness

Authors: Dannenberger, D.

Publication Name: ISSFAL International Congress, Stockholm, Sweden June 28 - July 1

Flaxseed oil supplementation increased plasma eicosapentaenoic acid proportion, but did not stimulate ketogenesis in healthy young and older adults

Authors: Hennebelle, M.

Publication Name: ISSFAL International Congress, Stockholm, Sweden June 28 - July 1

n3 fatty acid deficiency accelerated the impairment of mouse brain function induced by stored amyloid beta protein

Authors: Iwanaga, S.

Publication Name: ISSFAL International Congress, Stockholm, Sweden June 28 - July 1

Modifying dietary LA and ALA leads to favourable increases in n3 status: A systematic review

Authors: Mantzioris, E.

Publication Name: ISSFAL International Congress, Stockholm, Sweden June 28 - July 1

Dietary and Clinical Implications of FA Status in Children with Cystic Fibrosis

Authors: Magbool, A.

Publication Name: ISSFAL International Congress, Stockholm, Sweden June 28 - July 1

alpha linolenic acid reduces the growth of HER2overexpressing breast cancer cells that are sensitive or resistant to trastuzumab (TRAS) and prevents TRAS resistance development

Authors: Mason, J.

Publication Name: ISSFAL International Congress, Stockholm, Sweden June 28 - July 1

The alpha linolenic acid oxidative product protect immature neurons from oxidant injury and promote differentiation of oligodendrocyte progenitors

Authors: Minghetti, L.

Publication Name: ISSFAL International Congress Stockholm, Sweden June 28 - July 1

Modification of alpha linolenic acid and docosahexaenoic acid composition of milk from Chilean lactating women who received pre and post partum alpha linolenic acid intake from chia oil

Authors: Rodrigo, R.

Publication Name: ISSFAL International Congress, Stockholm, Sweden June 28 - July 1

Whole body synthesis rates of DHA from alpha linolenic acid are greater than brain DHA accretion and uptake rates in adult rats

Authors: Domenichiello, A.F. Chen, C.T. Trepanier, M-O. Stavro, P.M. Bazinet, R.P.

Publication Name: J Lipid Res

Bioaccessibility of lignans from ﬂaxseed (Linum usitatissimumL.) determined by single batch invitro simulation of the digestive process

Authors: Fuentealba, C. Figuerola, F. Esevez, A.M. Bastiasc, J.M. Munoza, O.

Publication Name: J Sci Food Agric

Diets high in monounsaturated and polyunsaturated fatty acids decrease fatty acid synthase protein levels in adipose tissue but do not alter other markers of adipose function and inﬂammation in diet-induced obese rats

Authors: Enns, J.E. Hanke, D. Park, A. Zahradka, P. Taylor, C.G.

Publication Name: Prostaglandins, Leukotrienes and Ess. Fatty Acids

Unsaturated fat intakes and mental health outcomes in young women from the Australian Longitudinal Study on Women's Health

Authors: Daley, C. Patterson, A. Sibbritt, D. MacDonald-Wicks, L.

Publication Name: Public Health Nutr.

Repeated versus single measurement of plasma omega 3 fatty acids and risk of heart failure

Authors: Djousse, L. Petrone, A.B. Weir, N.L. Hanson, N.Q. Glynn, R.J. Tsai, M.Y. Gaziano, J.M.

Publication Name: Eur J Nutr

Achieving optimal n3 fatty acid status: the vegarian's challenge…or not

Authors: Harris, W.S.

Publication Name: Am J Clin Nutr

Perinatal alpha linolenic acid availability alters the expression of genes related to memory and to epigenetic machinery, and the Mecp2 DNA methylation in the whole brain of mouse offspring

Authors: He, F. Lupu, D.S. Niculescu, M.D.

Publication Name: Int J Devl Neuroscience

Evidence for the use of glomerulomegaly as a surrogate marker of glomerular damage and for alpha linolenic acid rich oils in the treatment of early obesity related glomerulopathy in a diet induced rodent model of obesity

Authors: Caligiuri, S.P. Blydt-Hansen, T Love, K. Gregoire, M. Taylor, C.G. Zahradka, P. Aukema, H.M.

Publication Name: Appl Physiol Nutr Metab

The HYPERFlax trial for determining the anti HYPERtensive effects of dietary flaxseed in newly diagnosed stage 1 hypertensive patients: study protocol for a randomized, double blinded, controlled clinical trial

Authors: Caligiuri, S.P. Penner, B. Pierce, G.N.

Publication Name: Trials

Linoleic and alpha linolenic acids ameliorate streptozotocin induced diabetes in mice

Authors: Canetti, L. Werner, H. Leikin-Frenkel, A.

Publication Name: Arch Physiol Biochem

Association of Dietary, Circulating, and Supplement Fatty Acids with Coronary Risk A Systematic Review and Meta analysis

Authors: Chowdhury, R. Warnakula, S. Kunutsor, S. Crowe, F. Ward, H.A. Johnson, L. Franco, O.H. Butterworth, A.S. et al

Publication Name: Ann Intern Med

Erythrocyte membrane n3 fatty acid levels and carotid atherosclerosis in Chinese men and women

Authors: Dai, X. Zhang, B. Wang, P. Chen, C. Chen, Y. Su, Y.

Publication Name: Atherosclerosis

The impact of dietary fatty acids on macrophage cholesterol homeostasis

Authors: da Silva Afonsoa, M. Castihoa, G. Lavradora, M.S. Passarellia, M. Nakandakarea, E.R Lottenbergb, S.A. Lottenberga, A.M.

Publication Name: J Nutr Biochem

Anti-inflammatory Potential of Alpha Linolenic Acid Mediated Through Selective COX Inhibition: Computational and Experimental Data

Authors: Anand, R. Kaithwas, G.

Publication Name: Inflammation

Clustering effects on postprandial insulin secretion and sensitivity in response to meals with different fatty acid compositions

Authors: Bermudez, B. Ortega-Gomez, A. Varela, L.M. Villar, J. Abia, R. Muriana, F.J. Lopez, S.

Publication Name: Food Funct

Fatty acids and epigenetics

Authors: Burdge, G.C. Lillycrop, K.A.

Publication Name: Curr Opin Clin Nutri Metab Care

Alpha linolenic acid (ALA) from Rosa canina, sacha inchi and chia oils may increase ALA accretion and its conversion into n 3 LCPUFA in diverse tissues of the rat

Authors: Valenzuela, R. Barrera, C.R. Astorga, M.G. Sanhueza, J. Valenzuela, A.

Publication Name: Food Funct

Association between the intake of alpha linolenic acid and the risk of CHD

Authors: Vedtofte, M.S. Jakobsen, M.U. Lauritzen, L. O'Reilly, E.J. Virtamo, J. Knekt, P. Gcolditz, G. Hallmans, G. et al

Publication Name: Br J Nutr

Cross-Sectional Associations of Food Consumption with Plasma Fatty Acid Composition and Estimated Desaturase Activities in Finnish Children

Authors: Venalainen, T. Schwab, U. Agren, J. de Mello, V. Lindi, V. Eloranta, A.M. Kiiskinen, S. Laaksonen, D. et al

Publication Name: Lipids

Enhancing the intestinal absorption of low molecular weight chondroitin sulfate by conjugation with alpha linolenic acid and the transport mechanism of the conjugates

Authors: Xia, Y. Li, P. Cheng, Y. Zhang, X. Sheng, J. Wang, D. Li, J. Zhang, Q. et al

Publication Name: Intl. J. Pharm.

Dietary flaxseed intake exacerbates acute colonic mucosal injury and inflammation induced by dextran sodium sulfate

Authors: Zarepoor, L. Lu, J.T. Zhang, C. Wu, W. Lepp, D. Robinson, L. Wanasundara, J. Cui, S. et al

Publication Name: Am J Phys Gastrointest Liver Phys

Essential fatty acids in the treatment of dry eye syndrome: A myth or reality?

Authors: Al Mahmood, A.M. Al-Swailem, S.A.

Publication Name: Saudi J Ophthalmol

Comparing the Effects of Dietary Flaxseed and Omega-3 Fatty Acids Supplement on Cyclical Mastalgia in Iranian Women: A Randomized Clinical Trial

Authors: Vaziri, F. Lari, M.Z. Dehaghani, A.S. Salehi, M. Sadeghpour, H. Akbarzadeh, M. Zare, N.

Publication Name: Int J Family Med

Bioavailability and Potential Uses of Vegetarian Sources of Omega-3 Fatty Acids: A Review of the Literature

Authors: Lane, K. Derbyshire, E. Li, W. Brennan, C.

Publication Name: Crit Rev Food Sci Nutr

Food frequency questionnnaire as an indicator of the serum composition of essential n3 and n6 polyunsaturated fatty acids in early pregnancy, according to body mass index

Authors: Lepsch, J. Vaz, J.S. Moreira, J.D. Pinto, T.J.P. Soares-Mota, M. Kac, G.

Publication Name: J Hum Nutr Diet

17 beta Estradiol Increases Liver and Serum Docosahexaenoic Acid in Mice Fed Varying Levels of alpha Linolenic Acid

Authors: Mason, J.K. Kharotia, S. Wiggins, A.K.A. Kitson, A.P. Chen, J. Bazinet, R.P. Thompson, L.U.

Publication Name: Lipids

Both linoleic and linolenic acid prevent insulin resistance but have divergent impacts on skeletal muscle mitochondrial bioenergetics in obese Zucker rats

Authors: Matravadia, S. Herbst, E.A.F. Jain, S.S. Mutch, D.M. Holloway, G.P.

Publication Name: Am J Phy Endo Metab

The role of n6 and n3 polyunsaturated fatty acids in the manifestation of the metabolic syndrome in cardiovascular disease and nonalcoholic fatty liver disease

Authors: Monteiro, J. Leslie, M. Moghadasian, M.H. Arendt, B.M. Allard, J.P. Ma, D.W.L.

Publication Name: Food Function

No effect of n3 fatty acids supplementation on NT proBNP after myocardial infarction: The Alpha Omega Trial

Authors: Hoogeveen, E.K. Geleijnse, J.M. Kromhout, D. van't Sant, P. Gemen, E.F. Kusters, R. Giltay, E.J.

Publication Name: Eur J Prev Cardiol

Linoleic and a linolenic fatty acid consumption over three generations exert cumulative regulation of hepatic expression of genes related to lipid metabolism

Authors: Jacometo, C.B. Schmitt, E. Pfeifer, L.F.M. Schneider, A. Bado, F. da Rosa, F.T. Halfen, S. DelPino, F.A.B.

Publication Name: Genes Nutr

Molecular Structures and Metabolic Characteristics of Protein in Brown and Yellow Flaxseed with Altered Nutrient Traits

Authors: Khan, N.A. Booker, H. Yu, P.

Publication Name: J Agr Food Chem

Alpha Linolenic acid: Nutraceutical, pharmacological and toxicological evaluation

Authors: Kim, K. Namb, Y.A. Kim, H.S. Hayes, A.W. Lee, B.

Publication Name: Food Chem Toxicol

The effect of long term supplementation D with different dietary omega 6 to omega 3 ratios on mineral content and ex vivo prostaglandin E2 release in bone of growing rabbits

Authors: Alnouri, D.M. El-Din, M.F.S. Al-Khalifa, A.S.

Publication Name: Nut Res Prac

2013

Influence of diets to Wistar rats supplemented with soya, flaxseed and lupine products treated by lactofermentation to improve their gut health.

Authors: Bartkiene, E. Juodeikiene, G. Vidmantiene, D. Zdunczyk, Z. Juskiewicz, J. Cizeikiene, D. Matusevicius, P.

Publication Name: Int J Food Sci Nutr.

Alpha linolenic acid suppresses cholesterol and triacylglycerol biosynthesis pathway by suppressing SREBP2, SREBP1a and 1c expression.

Authors: Fukumitsu, S. Villareal, M.O. Onaga, S. Aida, K. Han, J. Isoda, H.

Publication Name: Cytotechnology

Effect of thermal heating on some lignans in flax seeds, sesame seeds and rye

Authors: Gerstenmeyer, E. Reimer, S. Berghofer, E. Schwartz, H. Sontag, G.

Publication Name: Food Chemistry

Daily flaxseed consumption improves glycemic control in obese men and women with pre-diabetes: a randomized study.

Authors: Hutchins, A.M. Brown, B.D. Cunnane, S.C. Domitrovich, S.G. Adams, E.R. Bobowiec, C.E.

Publication Name: Nutr. Res.

Lasting Effects on Body Weight and Mammary Gland Gene Expression in Female Mice upon Early Life Exposure to n3 but Not n6 HighFat Diets.

Authors: Luijten, M. Singh, A.V. Bastian, C.A. Westerman, A. Michele, M. Pisano, J. Pennings, L.A. Verhoef, A. et al.

Publication Name:

Flaxseed oil does not affect inflammatory markers and lipid profile compared to olive oil, in young, healthy, normal weight adults

Authors: Kontogianni, M.D. Vlassopoulos, A. Gatzieva, A. Farmaki, A-E. Katsiougiannis, S. Panagiotakos, D.B. Kalogeropoulos, N. et al.

Publication Name: Metabolism

Dietary intake and major sources of plant lignans in Latvian men and women.

Authors: Meija, L. Soderholm, P. Samaletdin, A. Ignace, G. Siksna, I. Joffe, R. Lejnieks, A. et al.

Publication Name: Int. J Food Sci Nutr.

Responses to oleic, linoleic and alpha linolenic acids in high carbohydrate, high fat diet induced metabolic syndrome in rats.

Authors: Poudyal, H. Kumar, S.A. Iyer, A. Waanders, J. Ward, L.C. Brown, L.

Publication Name: J Nutr. Biochem

Consumption of flaxseed, a rich source of lignans, is associated with reduced breast cancer risk.

Authors: Lowcock, E.C. Cotterchio, M. Boucher, B.A.

Publication Name: Cancer Causes Control

Development of botanical and fish oil standard reference materials for fatty acids.

Authors: Schantz, M.M. Sander, L.C. Sharpless, K.E. Wise, S.A. Yen, J.H. Pho, A.N. Betz, J.M.

Publication Name: Anal Bioanal Chem

An ethanolic extract of Linum usitatissimum caused cell lethality and inhibition of cell vitality proliferation of MCF7 and BT20 mamma carcinoma cells in vitro

Authors: Theil, C. Briese, V. Richter, D-U. Jeschke, U. Friese, K.

Publication Name: Arch Gynecol Obstet

Flaxseed – a nutritional punch

Authors: Ganorkar, P.M. Jain, R.K.

Publication Name: Inter Food Res J.

Beneficial effects of flaxseed oil and fish oil diet are through modulation of different hepatic genes involved in lipid metabolism in streptozotocin nicotinamide induced diabetic rats

Authors: Devarshi, P.P. Jangale, N.M. Ghule, A.E. Bodhankar, S.L. Harsulkar, A.M.

Publication Name: Genes Nutr.

The Effects of Dietary Flaxseed on Atherosclerotic Plaque Regression

Authors: Francis, A.A. Deniset, J.F. Austria, J.A. LaVallee, R.K. Maddaford, G.G. Hedley, T.E. Dibrov, E. Pierce, G.N.

Publication Name: Am J Physiol Heart Circ Physiol.

Radiation mitigating properties of the lignan component in flaxseed

Authors: Pietrofesa, R. Turowski, J. Tyagi, S. Dukes, F. Arguiri, E. Busch, T.M. Gallagher-Colombo, S.M. Solomides, C.C. Cengel, K.A. et al

Publication Name: BMC Cancer

Flaxseed (Linum usitatissimum L.) extract as well as(+)-secoisolaric- iresinol diglucoside and its mammalian derivatives are potent inhibitors of a-amylase activity.

Authors: Hano, C. Renouard, S. Molinie, R. Corbin, C. Barakzoy, E. Doussot, J. Lamblin, F. Laine, E.

Publication Name: Bio. Med. Chem. Letters

A Placebo-Controlled, Blinded, Randomized Clinical Trial of Dietary Flaxseed Supplementation for Children and Adolescents With Hypercholesterolemia

Authors: Wong, H. Chahal, N. Manlhiot, C. Niedra, E. McCrindle, B.W.

Publication Name: JAMA Pediatr.

Beneficial effect of flax seeds in streptozotocin (STZ) induced diabetic mice: isolation of active fraction having islet regenerative and glucosidase inhibitory properties

Authors: Dusane, M.B. Joshi, B.N.

Publication Name: Can. J. Physiol. Pharmacol

Extruded Flaxseed Meal Enhances the Nutritional Quality of Cereal-based Products

Authors: Giacomino, S. Penas, E. Ferreyra, V. Pellegrino, N. Fournier, M. Apro, N. Carrion, M.O. Frias, J.

Publication Name: Plant Foods Hum Nutr.

Effect of flaxseed flour incorporation on the physical properties and consumer acceptability of cereal bars

Authors: Khouryieh, H. Aramouni, F.

Publication Name: Food Sci. Tech. Intl.

Oils rich in linolenic acid independently protect against characteristics of fatty liver disease in the 6desaturase null mouse

Authors: Monteiro, J. Askarian, F. Nakamura, M.T. Moghadasian, M.H. Ma, D.W.L.

Publication Name: Can. J. Physiol. Pharmacol.

Microcapsule production employing chickpea or lentil protein isolates and maltodextrin: Physicochemical properties and oxidative protection of encapsulated flaxseed oil

Authors: Karaca, A.C. Nickerson, M. Low, N.H.

Publication Name: Food Chem.

Distribution, antioxidant and characterisation of phenolic compounds in soybeans, flaxseed and olives

Authors: Alu'datt, M.H. Rababah, T. Ereifej, K. Alli, I.

Publication Name: Food Chem.

No evidence of hypoglycemia or hypotension in older adults during 6 months of flax lignan supplementation in a randomized controlled trial: A safety evaluation

Authors: Billinsky, J. Glew, R.A. Cornish, S.M. Whiting, S.J. Thorpe, L.U. Alcom, J. Paus-Jenssen, L. Hadjistavropoulos, T. et al

Publication Name: Pharma Bio.

Use of defatted flaxseed meal reduces precancerous colon lesions in C57BL/6 mice 1

Authors: Gomides, A.F. de Paulal, S.O. Rosall, D.D. de Oliveiral, L.L. ComastriI, D.S. Peluzio, M.C.G.

Publication Name: Acta Cir Bras.

Increased bruising with the combination of long-chain omega-3 fatty acids, flaxseed oil and clopidogrel

Authors: Necyk, C. Ware, M.A. Amason, J.T. Tsuyuki, R.T. Boon, H. Vohra, S.

Publication Name: CPJ/RPC

Inhibitory effect of polyunsaturated fatty acids on apoptosis induced by Streptococcus pneumonia in alveolar macrophages

Authors: Saini, A. Harjai, K. Chhibber, S.

Publication Name: Indian J. Med. Res.

Flaxseed reverses atherosclerotic lesion formation and lowers lipoprotein (a) in ovarianhormone deficiency

Authors: Campbell, S.C. Bakhshalian, N. Sadaat, R.L. Lerner, M.R. Lightfoot, S.A. Brackett, D. Arjmandi, B.H.

Publication Name: J. NA Menopause Soc.

Controlled flax interventions for the improvement of menopausal symptoms and postmenopausal bone health: a systematic review

Authors: Dew, T.P. Williamson, G.

Publication Name: Menopause: The Jour. Of the N.Amer.Men. Soc.

Manifestations of Fasting-Induced Fatty Liver and Rapid Recovery from Steatosis in Voles Fed Lard or Flaxseed Oil Lipids

Authors: Mustonen, A-M. Karja, V. Kilpio, M. Tammi, R. Tammi, M. Rouvinen-Watt, K. Halonen, T. Nieminen, P.

Publication Name: Nutrients

Effects of Soy-Soluble Fiber and Flaxseed Gum on the Glycemic and Insulinemic Responses to Glucose Solutions and Dairy Products in Healthy Adult Males

Authors: Au, M.M.C. Goff, H.D. Kisch, J.A. Coulson, A. Wright, A.J.

Publication Name: J. Amer College Nutr.

A diet supplemented with ALA rich flaxseed prevents cardiomyocyte apoptosis by regulating Caveolin 3 expression

Authors: Carotenuto, F. Minieri, M. Monego, G. Fiaccavento, R. Bertoni, A. Sinigaglia, F. Vecchini, A. Carosella, L.

Publication Name: Cardiac Res.

Flax and Breast Cancer: A Systematic Review

Authors: Flower, G. Fritz, H. Balneaves, L.G. Verma, S. Skidmore, B. Fernandes, R. Kennedy, D. Cooley, K.

Publication Name: Inter. Canc. Ther.

Effect of Flaxseed (Flaxseed/Linseed) Fixed Oil against Distrinct Phases of Inflammation

Authors: Kaithwas, G. Majumdar, D.K.

Publication Name: ISRN Inflamm.

The Effects of Flaxseed Oil on Cadmium Induced Oxidative Stress in Rats

Authors: Karaca, S. Eraslan, G.

Publication Name: Bio. Trace Elem Res.

Synthesis and antioxidant evaluation of (S,S) and (R,R) secoisolariciresinol diglucosides (SDGs)

Authors: Mishra, O.P. Simmons, N. Tyagi, S. Pietrofesa, R. Shuvaev, V.V. Valiulin, R.A. Heretsch, P. Nicolaou, K.C.

Publication Name: Bio. Med. Chem Lett.

Changes in anthropometric measurements, body composition, blood pressure, lipid profile, and testosterone in patients participating in low-energy dietary intervention

Authors: Balliett, M. Burke, J.R.

Publication Name: J Chiro. Med.

Potent Antihypertensive Action of Dietary Flaxseed in Hypertensive Patients

Authors: Rodriguez-Leyva, D. Weighell, W. Edel, A.L. LaVallee, R. Dibrov, E. Pinneker, R. Maddaford, T.G. Ramjiawan, B. et al

Publication Name: Hypertension

Intake of fish and marine n3 polyunsaturated fatty acids and risk of breast cancer: metanalysis of data from 21 independent prospective cohort studies

Authors: Zheng, J-S. Hu, X-J. Zhao, Y-M. Yang, J. Li, D.

Publication Name: Brit. Med. J

Lignan Content of the Flaxseed Influences Its Biological Effects in Healthy Men and Women

Authors: Almario, R.U. Karakas, S.E.

Publication Name: J Amer. College Nutr.

Oxidative stability and sensory evaluation of microencapsulated flaxseed oil

Authors: Barroso, A.K.M. Pierucci, A.P.T.R. Freitas, S.P. Torres, A.G. Miguez da Rocha-Lea, H.

Publication Name: J Microencapsul.

Dietary Linoleic Acid and a-Linolenic Acid Differentially Affect Renal Oxylipins and Phospholipid Fatty Acids in Diet induced Obese Rats

Authors: Caligiuri, S.P.B. Love, K. Winter, T. Gauthier, J. Taylor, C.G. Blydt-Hansen, T. Zahradka, P. Aukema, H.M.

Publication Name: J. Nutr.

Interactions of dietary fibre and n3 rich oil with protein in surimi gels developed with salt substitute

Authors: Debusca, A. Tahergorabi, R. Beamer, S.K. Partington, S. Jaczynski, J.

Publication Name: Food Chem.

Flaxseed (Linum usitatissimum L.) and its Total Non digestible Fraction Influence the Expression of Genes Involved in Azoxymethane-induced Colon Cancer in Rats

Authors: Hernandez-Salazar, M. Guevara-Gonzalez, R.G. Cruz-Hernandez, A. Guevara-Olvera, L. Bello-Perez, L.A. Castano-Tostado, E. Loarca-Pina, G.

Publication Name: Plant Foods Hum Nutr.

Dietary flaxseed oil and fish oil modulates expression of antioxidant and inflammatory genes with alleviation of protein glycation status and inflammation in liver of streptozotocin nicotinamide induced diabetic rats

Authors: Jangale, N.M. Devarshi, P.P. Dubal, A.A. Ghule, A.E. Koppikar, S.J. Bodhankar, S.L. Chougale, A.D. Kulkarni, M.J.

Publication Name: Food Chem.

The Association of Red Blood Cell n3 and n6 Fatty Acids with Bone Mineral Density and Hip Fracture Risk in The Women's Health Initiative

Authors: Orchard, T.S. Ing, S.W. Lu, B. Belury, M.A. Johnson, K. Wactawski-Wende, J. Jackson, R.D.

Publication Name: J Bone Mineral Res.

Dietary supplementation with n3 polyunsaturated fatty acids ameliorates acute pneumonia induced by Klebsiella pneumoniae in BALB/c mice

Authors: Sharma, S. Chibber, S. Mohan, H. Sharma, S.

Publication Name: Can. J. Microbiol.

Antidepressive effect of polyphenols and omega3 fatty acid from pomegranate peel and flax seed in mice exposed to chronic mild stress

Authors: Naveen, S. Siddalingaswamy, M. Singsit, D. Khanum, F.

Publication Name: Psychiatry and Clin Neur

Tackling metabolic syndrome by functional foods

Authors: Khan, M.I. Anjum, F.M. Sohaib, M. Sameen, A.

Publication Name: Rev. Endo. Metab. Disord.

A diet high in alpha linolenic acid and monounsaturated fatty acids attenuates hepaticsteatosis and alters hepatic phospholipid fatty acid profile in diet-induced obese rats

Authors: Hanke, D. Zahradk, P. Mohankumar, S.K. Clark, J.L. Taylor, C.G.

Publication Name: Prostaglandins, Leukotrienes and Ess Fatty Acids

Anaphylaxis By Flaxseed

Authors: Alvarez-Perea, A. Alzate, D.P. Maldonado, A.D. Baeza, M.L.

Publication Name: J Invest Allergol Clin Immunol

Development of n3 rich energy bar with flaxseed

Authors: Mridula, D. Singh, K.K. Bamwal, P.

Publication Name: J Food Sci Technol

Secoisolariciresinol Diglucoside (SDG) Isolated from Flaxseed, An Alternative to Ace Inhibitors in the Treatment of Hypertension

Authors: Prasad, K.

Publication Name: Int J Angiol.

Omega to 6 polyunsaturated fatty acids: Is a broad cholesterol to lowering health claim appropriate?

Authors: Bazinet, R.P. Chu, M.W.A.

Publication Name: Med CMAJ

n3 Fatty Acid Intakes Are Inversely Related to Elevated Depressive Symptoms among United States Women

Authors: Beydoun, M.A. Kuczmarski, M.T.F. Beydoun, H.A. Hibbeln, J.R. Evans, M.K. Zonderman, A.B.

Publication Name: J.Nutr

The effects of a diet formulation with oats, soybeans, and flax on lipid profiles and uricemia in patients with AIDS and dyslipidemia

Authors: dos Santos Ferreira, R. Cassaro, D.C. Domingos, H. Pontes, E.R. Aiko, P.H. Carvalho de Meira, J.E.

Publication Name: Rev Soc Bras Med Trop

Linseed Dietary Fibers Reduce Apparent Digestibility of Energy and Fat and Weight Gain in Growing Rats

Authors: Kristensen, M. Knudsen, K.E.B. Jorgensen, H. Oomah, D. Bugel, S. Toubro, S. Tetens, I. Astrup, A.

Publication Name: Nutrients

Flaxseed Prevents leukocyte and Platelet Adhesion to Endothelial Cells in Experimental Atherosclerosis by Reducing sVCAM 1 and vWF

Authors: Haliga, R.E. Iancu, R.I. Butcovan, D. Mocanu, V.

Publication Name: Sci. World Jour.

Preparation and storage stability of flaxseed chutney powder, a functional food adjunct

Authors: Rao, P.P. Rao, G.N. Mala, K.S. Balaswamy, K. Satyanarayana, A.

Publication Name: J. Food Sci. Technol.

Dietary Flaxseed in Non-Small Cell Lung Cancer Patients Receiving Chemoradiation

Authors: Berman, A.T. Turowski, J. Mick, R. Cengel, K. Farnese, N. Basel-Brown, L. Mesaros, C. Blair, I.

Publication Name: J. Pulm. Resp. Med.

Effects of polyunsaturated fatty acids on the growth of gastric cancer cells in vitro

Authors: Dai, J. Shen, J. Pan, W. Shen, S. Das, U.N.

Publication Name: Lipids Health Dis.

Circulating and Dietary Omega 3 and Omega 6 Polyunsaturated Fatty Acids and Incidence of CVD in the Multi Ethnic Study of Atherosclerosis

Authors: de Oliveira Otto, M.C. Wu, J.H.Y. Baylin, A. Vaidya, D. Rich, S.S. Tsai, M.Y. Jacobs, D.R. Jr. Mozaffarian, D.

Publication Name: J Am Heart Assoc.

Alpha linolenic acid inhibits human renal cell carcinoma cell proliferation through PPARy activation and COX2 inhibition

Authors: Yang, L. Yuan, J. Liu, L. Shi, C. Wang, L. Tian, F. Liu, F. Wang, H. et al

Publication Name: Oncol Lett

Food sources and adequacy of intake of omega 3 and omega 6 fatty acids in a representative sample of Spanish adults

Authors: Anta, O. Rodriguez, G. Cruz, V. Sanchez, P. Vizuete, A. Sobaler, L.

Publication Name: Nutr. Hosp.

Marine and plant derived n minus 3 fatty acids differentially regulate prostate cancer cell proliferation

Authors: Eser, P.O. Vandenheuvel, J.P. Araujo, J. Thompson, J.T.

Publication Name: Mol Clin Oncol.

Bioconversion of alpha Linolenic Acid into n3 Long Chain Polyunsaturated Fatty Acid in Hepatocytes and Ad Hoc Cell Culture Optimisation

Authors: Alhazzaa, R. Sinclair, A.J. Turchini, G.M.

Publication Name: PLoS One

Lower Omega 3 Index is a Marker of Increased Propensity of Hypertensive Rat Heart to Malignant Arrhythmias

Authors: Bacova, B. Sec, P. Radosinska, J. Certik, M. Vachulova, A. Tribulova, N.

Publication Name: Physiol Res.

Effect of Alpha Linolenic Acid Supplementation on Serum Prostate Specific Antigen (PSA) Results from the Alpha Omega Trial

Authors: Brouwer, I.A. Geleijnse, J.M. Klaasen, V.M. Smit, L.A. Giltay, E.J. de Goede, J. Heijboer, A.C. Kromhout, D.et al

Publication Name: PLoS One

Case control and prospective studies of dietary alpha linolenic acid intake and prostate cancer risk a meta analysis

Authors: Carleton, A.J. Sievenpiper, J.L. de Souza, R. McKeown-Eyssen, G. Jenkins, D.J. Carleton, A.J. Sievenpiper, J.L. de Souza, R. et al

Publication Name: BMJ Open

N6 and N3 Fatty Acid Cholesteryl Esters in Relation to Fatal CHD in a Dutch Adult Population: A Nested Case Control Study and Meta Analysis

Authors: Goede, J. Verschuren, W.M. Boer, J.M. Verberne, L.D. Kromhout, D. Geleijnse, J.M.

Publication Name: PLoS One

Associations of Plasma Phospholipid and Dietary Alpha Linolenic Acid With Incident Atrial Fibrillation in Older Adults: The Cardiovascular Health Study

Authors: Fretts, A.M. Mozaffarian, D. Siscovick, D.S. Heckbert, S.R. McKnight, B. King, I.B. Rimm, E.B. Psaty, B.M. et al

Publication Name: J Am Heart Assoc.

Diet and Atrial Fibrillation: Does alpha Linolenic Acid, A Plant Derived Essential Fatty Acid, Have An Impact?

Authors: Kastner, D.W. Van Wagoner, D.R.

Publication Name: J Am Heart Assoc.

Investigating the Role of Polyunsaturated Fatty Acids in Bone Development Using Animal Models

Authors: Lau, B.Y. Cohen, D.J. Ward, W.E. Ma, D.W.

Publication Name: Molecules

Alternative Sources of Omega 3 Fats: Can We Find a Sustainable Substitute for Fish?

Authors: Lenihan-Geels, G. Bishop, K.S. Ferguson, L.R. Morales Jr., M.

Publication Name: Nutrients

The role of flaxseed and vitamin E on oxidative stress in prepubertal rats with experimental varicocele: An experimental study

Authors: Sohrabipour, S. Jafari, A. Kamalineiad, M. Sarrafnejd, A. Shahrestany, T. Sadeghipour, H-R

Publication Name: Iran J Reprod Med

Blood Level Omega 3 Fatty Acids as Risk Determinant Molecular Biomarker for Prostate Cancer

Authors: Sorongon-Legaspi, M.K. Chua, M. Sio, M.C. Morales Jr., M.

Publication Name: Prostate Cancer

Circulating Omega3 Polyunsaturated Fatty Acids and Subclinical Brain Abnormalities on MRI in Older Adults: The Cardiovascular Health Study

Authors: Virtanen, J.K. Siscovick, D.S. Lemaitre, R.N. Longstreth, W.T. Spiegelman, D. King, E.B. King, I.B. Mozaffarian, D.

Publication Name: J Am Heart Assoc.

Effect of n3 and n6 unsaturated fatty acids on prostate cancer (PC3) and prostate epithelial

Authors: Meng, H. Shen, Y. Shen, J. Zhou, F. Shen, S. Das, U.N.

Publication Name: Lipids Health Dis.

Cheek cell fatty acids reflect n 3 PUFA in blood fractions during linseed oil supplementation: a controlled human intervention study

Authors: Grindel, A. Staps, F. Kuhnt, K.

Publication Name: Lipids Health Dis.

Alpha linolenic acid improves insulin sensitivity in obese patients

Authors: Wang, D.Q. Liu, X.L. Rong, Q.F. Han, L. Zhao, N.Q. Zhonghua, Y.X.

Publication Name: Zhonghua Yi Xue Za Zhi.

Dietary fat, fatty acid intakes and colorectal cancer risk in Chinese adults: a case control study

Authors: Zhong, X. Fang, Y. Pan, Z. Li, B. Wang, L. Zheng, M. Chen, Y. Zhang, C.

Publication Name: Eur J Cancer Prev

Effects of flaxseed supplementation on erythrocyte fatty acids and multiple cardiometabolic biomarkers among Chinese with risk factors of metabolic syndrome

Authors: Zong, G. Demark-Wahnefried, W. Wu, H. Lin, X.

Publication Name: Eur J Nutr

The association between dietary omega-3 fatty acids and cardiovascular death: the Singapore Chinese Health Study

Authors: Koh, A.S. Pan, A. Wang, R. Odegaard, A.O. Pereira, M.A. Yuan, J. Koh, W.

Publication Name: Eur J Prev Cardiol.

2012

Effect of Flax Addition on the Flavor Proﬁle and Acceptability of Bagels

Authors: Aliani, M. Ryland, D. Pierce, G.N.

Publication Name: Journal of Food Science

Dietary walnuts inhibit colorectal cancer growth in mice by suppressing angiogenesis

Authors: Nagel, J.M. Brinkoetter, M. Magkos, F. Liu, X. Chamberland, J.P. Shah, S. Zhou, J. et.al.

Publication Name: Nutrition

Associations between n-3 PUFA concentrations and cognitive function after recovery from late-life depression

Authors: Chiu, C.-C. Frangou, S. Chang, C.-J. Chiu, W.-C. Liu, H.-C. Sun, I.-W. Liu, S.-I. et.al.

Publication Name: Am. J. Clin. Nutr.

Qualitative and quantitative analysis of the major phenolic compounds as antioxidants in barley and ﬂaxseed hulls using HPLC/MS/MS

Authors: Hao, M. Beta, T.

Publication Name: J. Sci. Food Agric

Flaxseed dietary ﬁber supplements for suppression of appetite and food intake

Authors: Ibrugger, S. Kristensen, M. Mikkelsen, M.S. Astrup, A.

Publication Name: Appetite

Studies on the protective effect of flaxseed oil on cisplatin-induced hepatotoxicity

Authors: Naqshbandi, A. Khan, W. Rizwan, S. Khan, F.

Publication Name: Human & Experimental Toxicology

High dietary ratio of omega-6 to omega-3 polyunsaturated acids during pregnancy and prevalence

Authors: da Rocha, C.M.M. Kac, G.

Publication Name: Maternal and Child Nutrition

Flaxseed gum from ﬂaxseed hulls: Extraction, fractionation, and characterization

Authors: Cui, S.W. Wu, Y. Goff, H.D.

Publication Name: Food Hydrocolloids

Flaxseed dietary fibers lower cholesterol and increase fecal fat excretion, but magnitude of effect depend on food type

Authors: Kristensen, M. Jensen, M.G. Aarestrup, J. Petersen, K.E.N. S�ndergaard, L. Mikkelsen, M.S. Astrup, A.

Publication Name: Nutrition & Metabolism

Omega-3 intake and Visual Acuity in Patients With Retinitis Pigmentosa Receiving Vitamin A

Authors: Berson, E.L. Rosner, B. Sandberg, M.A. Weigel-DiFranco, C. Willett, W.C.

Publication Name: Arch Ophthalmol.

Effect of omega-3 fatty acids supplementation on endothelial function: A meta-analysis of randomized controlled trials

Authors: Wang, Q. Liang, X. Wang, L. Lu, X. Huang, J. Cao, J. Li, H. Gu, D.

Publication Name: Atherosclerosis

Polyphenolic fractions improve the oxidative stability of microencapsulated linseed oil

Authors: Rubilar, M. Morales, E. Saez, R. Acevedo, F. Palma, B. Villarroel, M. Shene, C.

Publication Name: Eur. J. Lipid Sci. Technol.

Association between interaction and ratio of ω-3 and ω-6 polyunsaturated fatty acid and the metabolic syndrome in adults

Authors: Mirmiran, P. Hosseinpour-Niazi, S. Naderi, Z. Bahadoran, Z. Sadeghi, M. Azizi, F.

Publication Name: Nutrition

Attenuation of colonic inflammation by partial replacement of dietary linoleic acid with α-linolenic acid in a rat model of inflammatory bowel disease

Authors: Tyagi, A. Kumar, U. Reddy, S. Santosh, V.S. Mohammed, S.B. Ehtesham, N.Z. Ibrahim, A.

Publication Name: British Journal of Nutrition

�Metabolic syndrome� in the brain: deﬁciency in omega-3 fatty acid exacerbates dysfunctions in insulin receptor signalling and cognition

Authors: Agrawal, R Gomez-Pinilla, F.

Publication Name: J Physiol

Dietary flaxseed oil supplementation ameliorates the effect of cisplatin on brush border membrane enzymes and antioxidant system in rat intestine

Authors: Naqshbandi, A. Rizwan, S. Khan, W. Khan, F.

Publication Name: Hum Exp Toxicol

Supplementation of Milled Chia Seeds Increases Plasma ALA and EPA in Postmenopausal Women

Authors: Nieman, D.C. Sha, W. Xie, G. Qiu, Y. Jia, W.

Publication Name: Plant Foods Hum Nutr

Polyunsaturated fatty acids(PUFA) for attention deﬁcit hyperactivitydisorder (ADHD) in children and adolescents

Authors: Gillies, D. Sinn, J.K.H. Lad, S.S. Leach, M.J. Ross, M.J.

Publication Name: Cochrane Database of Systematic Reviews

In Vitro anti-metastatic activity of enterolactone, a mammalian lignan derived from flax lignan, and down-regulation of matrix metalloproteinases in MCF-7 and MDA MB 321 cell lines

Authors: Mali, A.V. Wagh, U.V. Hedge, M.V. Chandorkar, S.S. Surve, S.V. Patole, M.V.

Publication Name: Indian Journal of Cancer

Impact of flaxseed intake upon metabolic syndrome indicators in female Wistar rats.

Authors: Brant, L.H. Cardozo, L.F. Velarde, L.G. Boaventura, G.T

Publication Name: Acta. Cir. Bras.

Effects of Flaxseed Oil on Anti-oxidative System and Membrane Deformation of

Authors: Liu, L. Yang, W. Fu, J. Yu, M. Huang, Q. Wang, D. Xu, J. et. Al.

Publication Name: Lipids in Health and Disease

DietaryFlaxseedOilProtectsagainstBleomycin-Induced

Authors: Lawrenz, J. Herndon, B. Kamal, A. Mehrer, A. Dim, D.C. Baidoo, C. Gasper, D. et. al.

Publication Name: Pulmonary Medicine

Distribution of Cyclolinopeptides in Flaxseed Fractions and Products

Authors: Gui, B. Shim, Y.Y. Reaney, M.J.T.

Publication Name: J. Agric. Food Chem.

Lignans in seeds of Linum species

Authors: Schmidt, T.J. Klaes, M. Sendker, J.

Publication Name: Phytochemistry

Effects of flaxseed consumption on systemic inflammation and serum lipid profile in hemodialysis patients with lipid abnormalities.

Authors: Khalatbari, S.S. Jamaluddin, R. Tabibi, H. Mohd Yusof, B.N Atabak, S. Loh, S.P. Rahmani, L.

Publication Name: Hemodial Int.

Efficacy of omega-3 fatty acid supplementation on serum levels of tumour necrosis factor-alpha, C-reactive protein and interleukin-2 in type 2 diabetes mellitus patients.

Authors: Moghadam, A.M Saedisomeolia, A. Djalali, M. Djazayery, A. Pooya, S. Sojoudi, F.

Publication Name: Singapore Med J.

The association of red blood cell n-3 and n-6 fatty acids to dietary fatty acid intake, bone mineral density and hip fracture risk in the Women's Health Initiative.

Authors: Orchard, T.S. Ing, S.W. Lu, B. Belury, M.A. Johnson, K. Wactawski-Wende, J. Jackson, R.D.

Publication Name: J Bone Miner Res.

Effects of omega-3 fatty acids on postprandial triglycerides and monocyte activation.

Authors: Schirmer, S.H. Werner, C.M. Binder, S.B. Faas, M.E. Custodis, F. Bohm, M. Laufs, U.

Publication Name: Atherosclerosis.

Estradiol, Tamoxifen, and Flaxseed Alter IL – 1β and IL-1Ra Levels in Normal Human Breast Tissue in Vivo.

Authors: Abrahamsson, A. Morad, V. Saarinen, N.M. Dabrosin, C.

Publication Name: J Clin Endocrinol Metab.

Evaluation of the Influence of Whole and Defatted Flaxseed on Satiety, Glucose, and Leptin Levels of Women in the Late Postoperative Stage of Bariatric Surgery.

Authors: Cohen, L. Meira, J. cosendey, G.M. de Souza, A.F. Mattos, F. Carneiro, J.R. Rosado, E.L.

Publication Name: Obes Surg.

Production of secoisolariciresinol from defatted flaxseed by bacterial biotransformation.

Authors: Li, M.X. Zhu, H.Y. Yang, D.H. Ma, X.Q. Wang, C.Z. Cai, S.Q. Liu, G.R. Ku, B.S., Liu, S.L.

Publication Name: J Appl Microbiol.

Hepatoprottective potential of ether insoluble phenolic components of n-butanol fraction (EPC-BF) of flaxseed against CCI(4) – induced liver damage in rats.

Authors: Kasote, D.M. Badhe, Y.S. Zanwar, A.A. Hegde, M.V. Deshmukh, K.K.

Publication Name: J Pharm Bioallied Sci.

Prolonged consumption of flaxseed flour increases the 17b-estradiol hormone without causing adverse effects on the histomorphology of Wistar rats' penis.

Authors: de Franca Cardozo, L.F.M. Boaventura, G.T. Brant, L.H.C. Pereira, V.A. Velarde, L.G.C. Chagas, M.A.

Publication Name: Food & Chemical Toxicology

Evaluation of the Efficacy of Flaxseed Meal and Flaxseed Extract in Reducing Menopausal Symptoms

Authors: Colli, M.C. Bracht, A. Soares, A.A. de Oliveira, A.L. Boer, C.G. Marques de Souza, C.G. Peralta, R.M.

Publication Name: J Med Food

Potential Health Benefi ts of Bread Supplemented with Defatted Flaxseeds under Dietary Regimen in Normal and Type 2 Diabetic Subjects

Authors: Mohamed, D.A. Al-Okbi, S.Y. El-Hariri, D.M. Mousa, I.I.

Publication Name: Pol.J.Food Nutr.

Dietary intake and adipose tissue level of specific fatty acids in a selected group from the Lower Silesia population

Authors: Zatonska, K. Campos, H. Ilow, R. Janik-Koncewicz, K. Rozanska, D. Regulska-Ilow, B. Poltyn-Zaradna, K. Szuba, A.

Publication Name: Annals of Agr. & Env. Medicine

Flaxseed Lignan Complex Administration in Older Human Type 2 Diabetics Manages Central Obesity and Prothrombosis – An Invitation to Further Investigation into Polypharmacy Reduction

Authors: Barre, D.E. Mizier-Barre, K.A. Stelmach, E. Hobson, J. Griscti, O. Rudiuk, A. Muthuthevar, D.

Publication Name: J. Nutr. & Metab.

Differential vulnerability of substantia nigra and corpus striatum to oxidative insult induced by reduced dietary levels of essential fatty acids

Authors: Cardosa, H.D. Passos, P.P. Lagranha, C.J. Ferraz, A.C. Santos, E.F.Jr. Oliveira, R.S. Oliveira, P.E. Santos, R.de C.F.

Publication Name: Frontiers In Human Neuroscience

Roles of α-linolenic acid on IGF-I and GH/IGF system gene expression in porcine primary hepatocytes.

Authors: Fang, X-L. Shu, G. Zhang, Z-Q. Wang, S-B. Zhu, X-T. Gao, P. Xi, Q-Y. Zhang, Y-L.

Publication Name: Mol. Biol. Rep.

Type of vegetable oils used in cooking and risk of metabolic syndrome among Asian Indians

Authors: Lakshmipriya, N. Gayathri, R. Praseena, K. Vijayalakshmi, P. Geetha, G. Sudha, V. Krishnaswamy, K. et. al.

Publication Name: Int. J. of Food Sci.& Nutr.

Plasma Fatty Acid Composition in Patients with Pancreatic Cancer: Correlations to Clinical Parameters

Authors: Macasek, J. Vecka, M. Zak, A. Urbanek, M. Krechler, T.

Publication Name: Nutrition & Cancer

Effect of flaxseed supplementation and exercise training on lipid profile oxidative stress and inflammation in rats with myocardial ischemia.

Authors: Nounou, H.A. Deif, M.M.Shalaby, M.A.

Publication Name: Lipids in Health & Dis.

α-Linolenic acid and risk of cardiovascular disease: a systematic review and meta-analysis.

Authors: Pan, A. Chen, M. Chowdhury, R. Wu, J.H. Sun, Q. Campos, H. Mozaffarian, D. Hu, F.B.

Publication Name: Am. J. Clin. Nutr.

The role of essential fatty acids in the control of coronary heart disease

Authors: Vedtofte, M.S. Jakobsen, M.U. Lauritzen, L. Heitmann, B.L.

Publication Name: Clin. Nutr.

Flaxseed oil and alpha-lipoic acid combination reduces atherosclerosis risk factors in rats fed a high-fat diet

Authors: Xu, J. Yang, W. Deng, Q. Huang, Q. Yang, J. Huang, F.

Publication Name: Lipids in Health & Dis.

New insights into the health effects of dietary saturated and omega 6 and omega 3 polyunsaturated fatty acids.

Authors: de Longeril, M. Salen, P.

Publication Name: BMC Medicine

Water activity in dry foods containing live probiotic bacteria should be carefully considered: A case study with Lactobacillus rhamnosus GG in flaxseed.

Authors: Vesterlund, S. Salminen, K. Salminen, S.

Publication Name: Int. JFood Micro.

Potential Health Benefits of Bread Supplemented with Defatted Flaxseeds under Dietary Regimen in Normal and Type 2 Diabetic Subjects

Authors: Mohamed, D.A. Al-Okbi, S.Y. El-Hariri, D.M. Mousa, I.I.

Publication Name: Pol J Food Nutr Sci.

Flax Seed: A Potential Medicinal Food

Authors: Katare, C. Saxena, S. Agrawal, S. Prasad, GBKS Bisen, P.S.

Publication Name: J Nutr Food Sci.

Flaxseed energy and macronutrients balance

Authors: Goncalves de Oliveira, C. Rodrigues Ferreira Cruz, A.C. Mayumi Nakajima, V. Bressan, J. Goncalves Alfenas, R.C. Mattes, R.D. Brunoro Costa, N.M.

Publication Name: Nutr Hosp

Rheology, fatty acid profile and storage characteristics of cookies as influenced by flax seed (Linum usitatissimum)

Authors: Rajiv, J. Indrani, D. Prabhasankar, P. Rao, G.V.

Publication Name: J Food Sci Technol.

Effect of Flax Addition on the Flavor Profile and Acceptability of Bagels

Authors: Aliani, M. Ryland, D. Pierce, G.N.

Publication Name: JFood Sci.

Omega 3 Fatty Acids and Incident Type 2 Diabetes: A Systematic Review and Meta Anallysis

Authors: Wu,, J.H. Micha, R. Imamura, F. Pan, A. Biggs, M.L. Ajaz, O. Djousse, L. Hu, F.B. et al

Publication Name: Br J. Nutr.

2011

Dietary flaxseed administered post thoracic radiation treatment improves survival and mitigates radiation-induced pneumonopathy in mice

Authors: Christofidou-Solomidou, M. Tyagi, S. Tan, K.-S. Hagan, S. Pietrofesa, R. Dukes, F. Arguiri, E. et.al,

Publication Name: BMC Cancer

A Phase III, randomized, placebo-controlled, double-blind trial of flaxseed for the treatment of hot flashes: North Central Cancer Treatment Group N08C7

Authors: Pruthi, S. Qin, R. Terstreip, S.A. Liu, H. Loprinzi, C.L. Shah, T.R.C Tucker, K.F. et. Al.

Publication Name: Menopause

Metabolic and endocrine effects of long-chain versus essential omega-3 polyunsaturated fatty acids in polycystic ovary syndrome

Authors: Vargas, M.L.. Almario, R.U. Buchan, W. Kim, K. Karakas, S.E

Publication Name: Metabolism Clinical and Experimental

Effect of dietary fat and Omega-3 fatty Acids on Urinary Eicosanoids and Sex Hormone Concentrations in Postmenopausal Women: A Randomized Controlled Feeding Trial

Authors: Young, L.R. Kurzer, M.S. Thomas, W. Redmon, J.B. Raatz, S.K.

Publication Name: Nutrition and Cancer

Pilot, Prospective, Randomized, Double-masked, Placebo-controlled Clinical Trial of an Omega-3 Supplement for Dry Eye

Authors: Wojtowicz, J.C. Butovich, I. Uchiyama, E. Aronowicz, J. Agee, S. McCulley, J.P.

Publication Name: Cornea

Release of Angiotensin I-Converting Enzyme Inhibitory Peptides from Flaxseed (Linum usitatissimum L.) Protein under Simulated Gastrointestinal Digestion

Authors: Marambe, H.K. Shand, P.J. Wanasundara, J.P.D.

Publication Name: Journal of Agricultural and Food Chemistry

Flaxseed:A Potential Source of Food, Feed and Fiber

Authors: Singh, K.K. Mridula, D. Rehal, J. Barnwal, P.

Publication Name: Critical Reviews in Food Science and Nutrition

The effect of dietary ﬂaxseed on improving symptoms of cardiovascular disease in patients with peripheral artery disease

Authors: Leyva, D.R. Zahradka, P. Ramjiawan, B. Guzman, R. Aliani, M. Pierce, G.N.

Publication Name: Contemporary Clinical Trials

Flaxseed supplementation improved insulin resistance in obese glucose intolerant people: a randomized crossover design

Authors: Rhee, Y. Brunt, A.

Publication Name: Nutrition Journal

Polyunsaturated fatty acid levels in rat tissues after chronic treatment with dietetic oils

Authors: Rustichelli, C. Avallone, R. Campioli, E. Braghiroli, D. Baraldi, M.

Publication Name: J. Sci. Food Agric.

Dietary Intervention of Flaxseed: Effect on Serum Levels of IGF-1, IGF-BP3, and C-Peptide

Authors: Sturgeon, S.R. Volpe, S.L. Puleo, E. Bertone-Johnson, E.R. Heersink, J. Sabelawski, S. Wahala, K. et. al.

Publication Name: Nutrition and Cancer

Bleaching of defatted flaxseed meal to improve its usage as ingredient in food applications

Authors: Aider, M. Martel, A.-A.

Publication Name: International Journal of Food Science and Technology

Omega-3 fatty acids and incident type 2 diabetes: the Singapore

Authors: Brostow, D.P. Odegaard, A.O. Koh, W-P. Duval, S. Gross, M.D. Yuan, J-M. Pereira, M.A.

Publication Name: Am. J. Clin. Nutr.

Plasma omega-3 fatty acids and incident diabetes in older adults

Authors: Djousse, L. Biggs, M.L. Lemaitre, R.N. King, I.B. Song, X. Ix, J.H. Mukamal, K.J. Siscovick, D.S.

Publication Name: Am. J. Clin. Nutr.

The prevention of type 2 diabetes: should we recommend vegetable

Authors: Feskins, E.J.M.

Publication Name: Am. J. Clin. Nutr.

Flaxseed dietary fibers suppress postprandial lipemia and appetite sensation in young men.

Authors: Kristensen, M. Savorani, F. Christensen, S. Engelsen, S.B. Bugel, S. Toubro, S. Tetens, I. Astrup, A.

Publication Name: Nutr. Metab. Cardiovasc. Dis.

Consumption of polyunsaturated fatty acids, fish, and nuts and risk

Authors: Gopinath, B. Buyken, A.E. Flood, V.M. Empson, M. Rochtchina, E. Mitchell, P.

Publication Name: Am J Clin Nutr.

Dietary Intakes of Arachidonic Acid and a-Linolenic Acid Are Associated with Reduced Risk of Hip Fracture in Older Adults

Authors: Farina, E.K. Kiel, D.P. Roubenoff, R. Schaefer, E.J. Cupples, L.A. Tucker, K.L.

Publication Name: J. Nutr.

Implications of dietary a-linolenic acid in bone health.

Authors: Kim, Y. Ilich, J.Z.

Publication Name: Nutr. Metab. Cardiovasc. Dis.

Consumption of different sources of omega-3 polyunsaturated fatty acids by growing female rats affects long bone mass and microarchitecture.

Authors: Lukas, R. Gigliotti, J.C. Smith, B.J. Altman, S. Tou, J.C.

Publication Name: Bone

Dietary intake of n-3 and n-6 fatty acids and the risk of clinical depression in women: a 10-y prospective follow-up study

Authors: Lucas, M. Mirzaei, F. O'Reilly, E.J. Pan, A. Willett, W.C. Kawachi, I. Koenen, K. Ascherio, A.

Publication Name: Am. J. Clin. Nutr.

Intake of a-linolenic acid and other fatty acids in relation to the risk of bladder cancer: results from the New Hampshire case�control study

Authors: Brinkman, M.T. Karagas, M.R. Zens, M.S. Schned, A.R. Reulen, R.C. Zeegers, M.P.

Publication Name: Brit. J. Nutr.

Flaxseed cotyledon fraction reduces tumour growth and sensitises tamoxifen treatment of human breast cancer xenograft (MCF-7) in athymic mice

Authors: Chen, J. Saggar, J.K. Corey, P. Thompson, L.U.

Publication Name: Brit. J. Nutr.

Dietary flaxseed administered post thoracic radiation treatment improves survival and mitigates radiation-induced pneumonopathy in mice.

Authors: Christofidou-Solomidou, M. Tyagi, S. Tan, K-S. Hagan, S. Pietrofesa, R. Dukes, I. Arguiri, E. Heitjan, D.

Publication Name: BMC Cancer

Dietary Intervention of Flaxseed: Effect on Serum Levels of IGF-1, IGF-BP3, and C-Peptide.

Authors: Sturgeon, S.R. Volpe, S.L. Puleo, E. Bertone-Johnson, E.R. Heersink, J. Sabelawski, S. Wahala, K. Bigelow, C., Kurzer, M.S.

Publication Name: Nutr. & Cancer

Photoprotective effect of flax seed oil (Linum usitatissimum L.) against ultraviolet C-induced apoptosis and oxidative stress in rats.

Authors: Tuluce, Y. Ozkol, H. Koyuncu, I.

Publication Name: Toxicol. Ind. Health

Tamoxifen and Flaxseed Alter Angiogenesis Regulators in Normal Human Breast Tissue In Vivo

Authors: Aberg, U.W.N. Saarinen, N. Abrahamsson, A. Nurmi, T. Engblom, S. Dabrosin, C.

Publication Name: PLoS One

Leptin Reverts Pro-Apoptotic and Antiproliferative Effects of a-Linolenic Acids in BCR-ABL Positive Leukemic Cells: Involvement of PI3K Pathway

Authors: Beaulieu, A. Poncin, G. Belaid-Choucair, Z. Humblet, C. Bogdanovic, G. Lognay, G. Boniver, J. Defresne, M.-P.

Publication Name: PLoS One

Flaxseed and Breast Cancer: What Should We Tell Our Patients?

Authors: Patterson, R.E.

Publication Name: Journal of Clinical Oncology

(-)-Secoisolariciresinol attenuates high-fat diet-induced obesity in C57BL/6 mice

Authors: Tominaga, S. Nishi, K. Nishimoto, S. Akiyama, K. Yamauchi, S.

Publication Name: Food and Function

Effect of a Semi solid Formulation of Linum usitatissimum L. (Linseed) Oil on the Repair of Skin Wounds

Authors: de Souza Franco, E. Ferreira de Aquino, C.M. Lys de Medeiros, P. Evencio, L.B. da Silva Goes, A.J. de Souza Maia , M.B.

Publication Name: Evidence-Based Complementary and Alternative Medicine

Supplementation of Flaxseed Oil Diminishes Skin Sensitivity and Improves Skin Barrier Function and Condition

Authors: Neukam , K. De Spirt , S. Stahl, W. Bejot , M. Maurette , J.-M. Tronnier , H. Heinrich, U.

Publication Name: Skin Pharmacol. Physiol.

High- oleic rapeseed (canola) and ﬂaxseed oils modulate serum lipids and inﬂammatory biomarkers in hypercholesterolaemic subjects

Authors: Gillingham, L.G. Gustafson , J.A. Han, S.-Y. Jassal, D.S. Jones, P.J.H.

Publication Name: British Journal of Nutrition

Dietary a-linolenic acid, linoleic acid, and n�3 long-chain PUFA and risk of ischemic heart disease1�3

Authors: Vedtofte, M.S. Jakobsen, M.U. Lauritzen, L. Heitmann, B.L.

Publication Name: Am. J. Clin. Nutr.

Dietary a-linolenic acid diminishes experimental atherogenesis and restricts T cell-driven inﬂammation

Authors: Winnik, S. Lohmann, C. Richter, E.K. Schafer, N. Song, W.-L. Leiber, F. Mocharla, P. et. al.

Publication Name: European Heart Journal

Linseed Oil: An Investigation of its Antiarthritic Activity in Experimental Models

Authors: Singh, S. Nair, V. Gupta, Y.K.

Publication Name: Phytotherapy Research

Cardioprotective activity of flax lignan concentrate extracted from seeds of Linum usitatissimum in isoprenalin induced myocardial necrosis rats

Authors: Zanwar, A.A. Hedge, M.V. Bodhankar, S.L.

Publication Name: Interdiscip. Toxicol.

Flaxseed and its contribution to body growth and brain of Wistar rats during chidhood and adolescence

Authors: Ferreira Costa Leite, C.D. Calvi Lenzi de Almeida,K. Guzman-Silva, M.� A. Azevedo de Meneses, J. teles Boaventura, G.

Publication Name: Nutr. Hosp.

Consumption of different sources of omega-3 polyunsaturated fatty acids by growing female rats affects long bone mass and microarchitecture

Authors: Lukas, R. Gigliotti, J.C. Smith, B.J. Altman, S. Tou, J.C.

Publication Name: Bone

Effects of Flaxseed Oil on Lead Acetate-Induced Neurotoxicity in Rats

Authors: Abdel Moneim, A.E. Al-Quraishy, S.

Publication Name: Biol. Trace Elem. Res.

Low-and High-Dose Plant and Marine (n-3) Fatty Acids Do Not Affect Plasma Inﬂammatory Markers in Adults with Metabolic Syndrome

Authors: Dewell, A. Marvasti, F.F. Harris, W.S. Tsao, P. Gardner, C.D.

Publication Name: Journal of Nutrition

The alpha linolenic acid content of flaxseed can prevent the atherogenic effects of dietary trans fat

Authors: Bassett, C.M.C. McCullough, R.S. Edel, A. L. Patenaude, A. LaVallee, R.K. Pierce, G.N.

Publication Name: Am. J. Physiol. Heart Circ. Physiol.

Essential fats: how do they affect growth and development of infants and young children in developing countries? A literature review

Authors: Huffman, S.L. Harika, R.K. Eilander, A. Osendarp, S.J.M.

Publication Name: Maternal & Child Nutrition

Alpha-Linolenic Acid Intake and 10-Year Incidence of Coronary Heart Disease and Stroke in 20,000 Middle Aged Men and Women in The Netherlands

Authors: de Goede, J. Verschuren, W.M.M. Boer, J.M.A. Kromhout, D. Geleijnse, J.M.

Publication Name: PLoS One

Adipocyte morphology and leptin signaling in rat offspring from mothers supplemented with ﬂaxseed during lactation

Authors: Sarto Figueiredo, M. Cottini da Fonseca Passos, M. Hara Trevenzoli, I. Andrade Troina, A. Santana Carlos, A. Alves Nascimento-Saba, C.C. Carneiro Fraga, M. et. al.

Publication Name: Nutrition & Metabolism

When balanced for precursor fatty acid supply echium oil is not superior to linseed oil in enriching lamb tissues with long-chain n-3 PUFA

Authors: Kitessa, S.M. Young, P. Nattrass, G. Gardner, G. Pearce, K. Pethick, D.W.

Publication Name: British Journal of Nutrition

Dietary fatty acid composition during pregnancy and the risk of asthma in the offspring

Authors: Lumia, M. Luukkainen, P. Tapanainen, H. Kaila, M. Erkkola, M. Uusitalo, L. Niinist�, S. et.al.

Publication Name: Pediatric Allergy and Immunology

The Alpha Linolenic Acid Content of Flaxseed is Associated with an Induction of Adipose Leptin Expression

Authors: McCullough, R.S. edel, A.L. Bassett, C.M.C. LaVall�e, R.K. Dibrov, E. Blackwood, D.P. Ander, B.P. Pierce, G.N.

Publication Name: Lipids

Maternal α-linolenic acid availability during gestation and lactation alters the postnatal hippocampal development in the mouse offspring

Authors: Niculescu, M.D. Lupu, D.S. Craciunescu, C.N.

Publication Name: International Journal of Developmental Neuroscience

α-linolenic acid prevents endoplasmic reticulum stress-mediated apoptosis of stearic acid lipotoxicity on primary rat hepatocytes

Authors: Zhang, Y. Dong, L. Yang, X. Shi, H. Zhang, L.

Publication Name: Lipids in Health and Disease

Postprandial lipid responses to an alpha-linolenic acid-rich oil, olive oil and butter in women: A randomized crossover trial

Authors: Svensson, J. Rosenquist, A. Ohlsson, L.

Publication Name: Lipids in Health and Disease

Different Sources of Omega-3 Polyunsaturated Fatty Acids Affects Apparent Digestibility, Tissue Deposition, and Tissue Oxidative Stability in Growing Female Rats

Authors: Tou, J.C. Altman, S.N. Gigliotti, J.C. Benedito, V.A. Cordonier, E.L.

Publication Name: Lipids in Health and Disease

Hematologic and immunological indicators are altered by chronic intake of flaxseed in Wistar rats

Authors: Ferreira Medeiros de Franca Cardoza, L. Leal Soares, L. Cardozo Brant, L.H. Alves Chagas, M. Alves Pereira, V. Coca Velarde, L.G. Teles Boaventura, G.

Publication Name: Nutr. Hosp.

Influence of omega-3 fatty acids from the flaxseed (Limum usitatissimum) on the brain development of newborn rats

Authors: Lenzi Almeida, K.C. Teles Boaventura, G. Guzman Silva, M.A.

Publication Name: Nutr. Hosp.

Cardioprotective activity of flax lignan concentrate extracted from seeds of Linum usitatissimum in isoprenalin induced myocardial necrosis in rats

Authors: Hedge, M.V. Bodhankar, S.L.

Publication Name: Interdiscip. Toxicol.

Lignan transformation by gut bacteria lowers tumor burden in a gnotobiotic rat model of breast cancer

Authors: Mabrok,H.B. Klopﬂeisch, R. Ghanem, K.Z. Clavel, T. Blaut, M. Loh, G.

Publication Name: Carcinogenesis

Omega-3 Fatty Acids and Cardiovascular Disease Effects on Risk Factors, Molecular Pathways, and Clinical Events

Authors: Mozaffarian, D. Wu, J.H.Y.

Publication Name: Journal of the American College of Cardiology

Eﬀects of phytoestrogen extracts isolated from ﬂax on hormone

Authors: Richter, D.U. Abarzua, S. Chrobak, M. Piechulla, B. Vrekoussis, T. Makrigiannakis, A Scholz, C. et.al.

Publication Name: Gynecological Endocrinology

Walnut oil increases cholesterol efflux through inhibition of stearoyl CoA desaturase 1 in THP-1 macrophage-derived foam cells

Authors: Zhang, J. Grieger, J.A. Kris-Etherton, P.M. Thompson, J.T. Gillies, P.J. Fleming, J.A. Vanden Heuvel, J.P.

Publication Name: Nutrition & Metabolism

High dose of an n-3 polyunsaturated fatty acid diet lowers activity of C57BL/6 mice

Authors: Rockett, B.D. Harris, M. Shaikh, S.R.

Publication Name: Prostaglandins,

Nutritional quality of fermented defatted soya and ﬂaxseed ﬂours and their effect on texture and sensory characteristics of wheat sourdough bread

Authors: Bartkiene, E. Juodeikiene, G. Vidmantiene, D.

Publication Name: International Journal of Food Sciences and Nutrition

Unsaturated Fatty Acids Revert Diet-Induced Hypothalamic Inflammation in Obesity

Authors: Cintra, D.E. Ropelle, E.R. Moraes, J.C. Pauli, J. R. Morari, J. de Souza, C.T. Grimaldi, R. et.al.

Publication Name: PLoS ONE

Sex differences in the relationship of dietary fatty acids to cognitive measures in American children

Authors: Lassek, W.D. Gaulin, S.J.C.

Publication Name: Frontiers in Evolutionary Neuroscience

An Open-Label Study on the Effect of FlaxSeed Powder (Linum usitatissimum) Supplementation in the Management of Diabetes Mellitus

Authors: Mani, U.V. Mani, I. Biswas, M. Kumar, S.N.

Publication Name: Journal o f Dietary Supplements

Effect of a linseed diet on lipogenesis, fatty acid composition and stearoyl-CoA-desaturase in rabbits

Authors: Benatmane, F. Kouba, M. Youyou, A. Mourot, J.

Publication Name: Animal

Tamoxifen and Flaxseed Alter Angiogenesis Regulators

Authors: Nilsson Aberg, U.W. Saarinen, N. Abrahamsson, A. Nurmi, T. Engblom, S. Dabrosin, C.

Publication Name: PLoS One

The antiatherogenic, renal protective and immunomodulatory effects of purslane, pumpkin and flax seeds on hypercholesterolemic rats

Authors: Lamiaa, A Barakat, A. Hamed Mahmoud, R.

Publication Name: N Am J Med Sci

Antiinflammatory, analgesic and antipyretic activities of Linum usitatissimum L. (flaxseed/linseed) fixed oil

Authors: Kaithwas, G. Mukherjee, A. Chaurasia, A.K. Majumdar, D.K.

Publication Name: Indian Journal of Experimental Biology

Dietary α-linolenic acid�rich formula reduces adhesion molecules in rats with experimental colitis

Authors: Ibrahim, A. Aziz, M. Hassan, A. Mbodji, K. Collasse, E. Co�ffier, M. Bounoure, F. et.al.

Publication Name: Nutrition

The protective effect of flaxseed oil on lead acetate-induced renal toxicity in rats

Authors: Moneim, A.E.A. Dkhila, M.A. Al-Quraishy, S.

Publication Name: Journal of Hazardous Materials

Omega-3 fatty acids and metabolic syndrome: Effects and emerging mechanisms of action

Authors: Poudyal, H. Panchal, S.K. Diwan, V. Brown, L.

Publication Name: Progress in Lipid Research

Antimicrobial Investigation of Linum usitatissimum for the Treatment of Acne

Authors: Nand, P. Drabu, S. Gupta, R.K.

Publication Name: Natural Product Communications

(n3) Fatty Acids Alleviate Adipose Tissue Inflammation and Insulin Resistance: Mechanistic Insight

Authors: Kalupahana, N.S. Claycombe, K.J. Moustaid-Moussa, N.

Publication Name: Adv Nutr.

Characterists of Flaxseed Oil from Two Different Flax Plants.

Authors: Zhang, Z-S. Wang, L-J Li, D. Li, S-J Ozkan, N.

Publication Name: Intern Food Prop.

Effect of In vitro Human Digestion on the Viscosity of Hydrocolloids in Solution: A Dietary Fibre Study

Authors: Hrvoje, F.

Publication Name: University of Guelph

Functional Properties of Linseed Meal Fractions: Application as Nutraceutical Ingredient

Authors: Stark, Y.Y. Muller, K. Kawarada, H. Futagawa, K. Nakada, R. Tashiro, Y.

Publication Name: Food Sci Technol Res.

In vivo, In vitro Evaluation of Linseed Mucilage Based Buccal Mucoadhesive Microspheres of Venlafaxine

Authors: Padmaker Nerkar, P. Gattani, S.

Publication Name: Drug Delivery

Genetic Variation in StearoylCoA Desaturase 1 Is Associated with Metabolic Syndrome Prevalence in Costa Rican Adults

Authors: Gong, J. Campos, H. McGarvey, S. Wu, Z. Goldberg, R. Baylin, A.

Publication Name: J. Nutr.

2010

Oxidative stability and lipid components of eggs from flax-fed hens: Effect of dietary antioxidants and storage

Authors: Hayat, Z. Cherian, G. Pasha, T.N. Khattak, F.M. Jabber, M.A.

Publication Name: Poultry Science

Tamoxifen, flaxseed and the lignan enterolactone increase stroma and cancer cell derived IL-1Ra and decrease tumor angiogenesis in estrogen dependent breast cancer

Authors: Lindahl, G. Saarinen, N.M. Abrahamsson, A. Dabrosin, C.

Publication Name: Cancer Research

Consumption of a Flaxseed-Rich Food is not More Effective than a Placebo in Alleviating the Climacteric Symptoms of Postmenopausal Women

Authors: Simbalista, R.L. Sauerbronn, A.V. Aldrighi, J.M. Aras, J.A.G.

Publication Name: The Journal of Nutrition

Effect of Flaxseed Consumption on Urinary Levels of Estrogen Metabolites in Postmenopausal Women

Authors: Sturgeon, S.R.

Publication Name: Nutrition and Cancer

Protective Effect of Flaxseed Oil on Renal Injury in Hyperlipidaemic Rats: The Effect of Flaxseed Oil on Hyperlipidaemia

Authors: Akpolat, M. Kanter, M. Topcu-Tarladacalisir, Y. Aydogdu, N.

Publication Name: Phytotherapy Research

Flax oil-mediated activation of PPAR-ƴ correlates with reduction of hepatic lipid accumulation in obese spontaneously hypertensive/NDmcr-cp rats, a model of the metabolic syndrome

Authors: Chechi, K. Yasui, N. Ikeda, K. Yamori, Y. Cheema, S.K.

Publication Name: British Journal of Nutrition

Lymphatic absorption of α-linolenic acid in rats fed flaxseed oil-based emulsion

Authors: Coudelo, L. Bou-Vaysse, C. Fonseca, L. Montesinos, E. Djoukitch, S. Combe, N. Cansell, M.

Publication Name: British Journal of Nutrition

Antioxidant and Angiotensin Converting Enzyme-Inhibitory Properties of a Flaxseed Protein-Derived High Fischer Ratio Peptide Mixture

Authors: Udenigwe, C.C. Aluko, R.E.

Publication Name: Journal of Agricultural and Food Chemistry

Hypolipidemic and heptoprotective seeds mixture diet rich in omega-3 and omega-6 fatty acids

Authors: Makni, M. Fetoui, H. Garoui, E.M. Gargouri, N.K. Jaber, H. Makni, J. Boudawara. T. Zeghal, N.

Publication Name: Food and Chemical Toxicology

Effect of Flax Seeds and Date Palm Leaves Extracts on Serum Concentrations of Glucose and Lipids in Alooxan Diabetic Rats

Authors: Abuelgassim, A.O.

Publication Name: Pakistan Journal of Biological Sciences

Antidiabetic effect of ﬂax and pumpkin seed mixture powder: effect on hyperlipidemia and antioxidant status in alloxan diabetic rats

Authors: Makni, M. Fetoui, H. Gargouri, N.K. Garoui, E.M. Zeghal, N.

Publication Name: Journal of Diabetes and Its Complications

Dietary Milled Flaxseed and Flaxseed Oil Improve N-3 Fatty Acid Status and Do Not Affect Glycemic Control in Individuals with Well-Controlled Type 2 Diabetes

Authors: Taylor, C.G. Noto, A.D. Stringer, D.M. Froese, S. Malcolmson, L.

Publication Name: Journal of the American College of Nutrition

Alpha-Linolenic Acid: Is It Essential to Cardiovascular Health

Authors: Geleijnse, J.M. de Goede, J. Brouwer, I.A.

Publication Name: Curr. Atheroscler. Rep.

Identification of the 100 richest dietary sources of polyphenols: an application of the Phenol-Explorer database.

Authors: Perez-Jiminez, J. Neveu, V. Vos, F. Scalbert, A.

Publication Name: Euro. J.Clin. Nutr.

Influence of high-fat diet from differential dietary sources on bone mineral density bone strength and bone fatty acid composition in rats.

Authors: Laul, B.M. Fajardo, V.A. McMeekin, L. Sacco, S.M. Ward, W.E. Roy, B.D. Peters, S.J. Leblanc, P.J.

Publication Name: Appl. Physiol. Nutr. Metab.

Randomized, placebo-controlled trial of flax oil in pediatric bipolar disorder.

Authors: Gracious, B.L. Chirieac, M.C. Costescu, S. Finucane, T.L. Youngstrom, E.A. Hibbelin, J.R.

Publication Name: Bipolar Disorders

Dietary flaxseed lignan or oil combined with tamoxifen

Authors: Saggar, J.K. Chen, J. Corey, P. Thompson, L.U.

Publication Name: Mol.Nutr.Food Res.

Flaxseed oil reduces the growth of human breast tumors (MCF-7) at high levels of circulating estrogen.

Authors: Truan, J.S. Chen, J-M. Thompson, L.U.

Publication Name: Mol. Nutr. Food Res.

Exposure to flaxseed during lactation does not alter prostate area

Authors: Cardoza, L.F.M. Chagas, M.A. Soares, L.L. Troina, A.A. Bonaventura, G.T.

Publication Name: Nutr. Hosp.

Flaxseed Lignans: Source, Biosynthesis, Metabolism, Antioxidant Activity, Bio-Active

Authors: Toure, A. Xueming, X.

Publication Name: Inst. Of Food Tech.

Role of dietary fatty acids in mammary gland development and breast cancer

Authors: MacLennan, M. Ma, D.W.L.

Publication Name: Breast Cancer Research

Lymphatic absorption of a -linolenic acid in rats fed ﬂaxseed oil -based emulsion

Authors: Couedelo, L. Bou-Vaysse, C. Fonseca, L. Montesinos, E. Djoukitch, S. Combe, N. Cansell, M.

Publication Name: British Journal of Nutrition

Linseed oil in the maternal diet increases long chain- PUFA status of the foetus and the newborn

Authors: de Quelen, F. Boudry, G. Mourot, J.

Publication Name: British Journal of Nutrition

Lower Efﬁcacy in the Utilization of Dietary ALA as Compared to Preformed EPA + DHA on Long Chain n-3 PUFA Levels in Rats

Authors: Talahalli, R.R. Vallikannan, B. Sambaiah, K. Lokesh, B. R.

Publication Name: Lipids

Omega 3 long chain fatty acid synthesis is regulated more by substrate levels than gene expression

Authors: Tu, W.C. Cook-Johnson, R.J. James , M.J. Muhlhausler, B.S. Gibson, R.A.

Publication Name: Prostaglandins, Leukotrienes and Essential Fatty Acids

Deposition of docosahexaenoic acid (DHA) is limited in forebrain of young obese fa/fa Zucker rats fed a diet high in α-linolenic acid but devoid of DHA

Authors: Zhao, J. Gillam, M.E. Gillam, M.E. Taylor, C.G. Weiler, H.A.

Publication Name: Journal of Nutritional Biochemistry

Mechanisms underlying the cardioprotective effects of omega-3 polyunsaturated fatty acids

Authors: Adkins, Y. Kelley, D.S.

Publication Name: Journal of Nutritional Biochemistry

Hypertension induced by omega-3 polyunsaturated fatty acid deﬁciency is alleviated by alpha-linolenic acid regardless of dietary source

Authors: Begg, D.P. Sinclair, A.J. Stahl, L.A. Premaratna, S.D. Hafandi, A. Jois, M. Weisinger . R.S.

Publication Name: Hypertension Research

Alpha-Linolenic Acid: Is It Essential to Cardiovascular Health?

Authors: Geleijnse, J.M. de Goede, J. Brouwer, I.A.

Publication Name: Curr. Atheroscler. Rep.

Omega-3 fatty acids and lipoprotein associated phospholipase A2 in healthy older adult males and females

Authors: Nelson , T.L. Hokanson, J.E. Hickey. M.S.

Publication Name: Eur. J. Nutr.

Elevated plasma ﬁbrinogen caused by inadequate a-linolenic acid intake can be reduced by replacing fat with canola-type rapeseed oil

Authors: Seppanen-Laakso, T. Laakso, I. Lehtimaki, T. Rontu, R. Moilanen, E. Solakivi, T. Seppo, L. et. al.

Publication Name: Prostaglandins, Leukotrienes and Essential Fatty Acids

Consumption of a Flaxseed-Rich Food Is Not More Effective Than a Placebo in Alleviating the Climacteric Symptoms of Postmenopausal Women 1,2

Authors: Simbalista, R.L. Sauerbronn A.V. Aldrighi J.M. Areas, J.A.G.

Publication Name: J. Nutr.

Effects of Diets High in Walnuts and Flax Oil on Hemodynamic Responses to Stress and Vascular Endothelial Function

Authors: West, S.G. Likos Krick, A. Cousino Klein, L. Zhao, G. Wojtowicz, T.F. McGuiness, M. Bagshaw, D.M. et. al.

Publication Name: Journal of the American College of Nutrition

Lifestyle Counseling and Supplementation with Flaxseed or Walnuts Inﬂuence the Management of Metabolic Syndrome1�4

Authors: Wu, H. Pan, A. Yu, Z. Qi, Q. Lu, L. Zhang, G. Yu, D. et. al.

Publication Name: J. Nutr.

Health effects with consumption of the ﬂax lignan secoisolariciresinol diglucoside

Authors: Adolphe, J.L. Whiting, S.J. Juurlink, B.H.J. Thorpe, L.U. Alcorn, J.

Publication Name: British Journal of Nutrition

Flaxseed lignan lowers blood cholesterol and decreases liver disease risk factors in moderately hypercholesterolemic men

Authors: Fukumitsu, S. Aida, K. Shimizu, H. Toyoda, K.

Publication Name: Nutrition Research

Exposure to flaxseed during lactation does not alter prostate area or epithelium height but changes lipid profile in rats

Authors: Ferreira Medeiros, L. Alves Chagas, M. Leal Soares, L. Andrade Troina, A. Teles Bonaventura, G.

Publication Name: Nutr. Hosp.

Dietary lignans: physiology and potential for cardiovascular disease risk reduction

Authors: Peterson, J. Dwyer, J. Adlercreutz, H. Scalbert, A. Jacques, P. McCullough, M.L.

Publication Name: Nutrition Reviews

Flaxseed Ingestion Alters Ratio of Enterolactone Enantiomers in Human Serum

Authors: Saarinen, N.M. Smeds, A.I. Penalvo, J.L. Nurmi, T. Adlercreutz, H. Makela, S.

Publication Name: Journal of Nutrition and Metabolism

Production of enterodiol from defatted flaxseeds through biotransformation by human intestinal bacteria

Authors: Wang, C.-Z. Ma, X.-Q. Yang, D.-H. Guo, Z.-R. Liu, G.-R. Zhao, G.-X. Tang, J. et. al.

Publication Name: BMC Microbiology

The Consumption of Food Products from Linseed-Fed Animals Maintains Erythrocyte Omega-3 Fatty Acids in Obese Humans

Authors: Legrand, P. Schmitt, B. Mourot, J. Catheline, D. Chesneau, G. Mireaux, M. Kerhoas, N. Weill, P.

Publication Name: Lipids

High habitual dietary α-linolenic acid intake is associated with decreased plasma soluble interleukin-6 receptor concentrations in male twins

Authors: Dai, J. Ziegler, T.R. Bostick, R.M. Manatunga, A.K. Jones, D.P. Goldberg, J. Miller, A. et.al.

Publication Name: Am. J. Clin. Nutr.

Agonism with the omega-3 fatty acids a-linolenic acid and docosahexaenoic acid mediates phosphorylation of both the short and long isoforms of the human GPR120 receptor

Authors: Burn, R.N. Moniri, N.H.

Publication Name: Biochemical and Biophysical Research Communications

Age-related changes of n-3 and n-6 polyunsaturated fatty acids in the

Authors: Conklin, S.M. Runyan, C.A. Leonard, S. Reddy, R.D. Muldoon,M.F. Yao, K.J.

Publication Name: Prostaglandins, Leukotrienes and Essential Fatty Acids

Omega-3 Fatty Acids

Authors: DeFilippis, A.P. Blaha, M.J. Jacobson, T.A.

Publication Name: Current Treatment Options in Cardiovascular Medicine

Dietary ω-3 fatty acid and ω-3: ω-6 fatty acid ratio predict improvement in glucose disturbances in Japanese Brazilians

Authors: Sartorelli, D.S. Dami�o, R. Chaim, R. Hirai, A. Gimeno, S.G.A. Ferreira, S.R.G.

Publication Name: Nutrition

Flaxseed as a Source of Functional Ingredients

Authors: Rubilar, M. Gutierrez, C. Verdugo, M. Shene, C. Sineiro, J.

Publication Name: J Soil Sci Plant Nutr.

Nutritional Characteristics of Linseed/Flaxseed (Linum Usitatissimum) And Its Application in Muffin Making

Authors: Chetana, M.S Sudha, M.L. Begum, K. Ramasarma, P.R.

Publication Name: J Texture Studies

Consumption of omega 3 fatty acids and fish and risk of age related hearing loss

Authors: Gopinath, B. Flood, V.M. Rochtchina, E. McMahon, C.M. Mitchell, P.

Publication Name: Am J Clin Nutr.

Fatty acids in serum phospholipids and carotid intima media thickness in Spanish subjects with primary dyslipidemia

Authors: SalaVila, A. Cofan, M. PerezHeras, A. Nunez, I. Gilabert, R. Junyent, M. et al

Publication Name: Am J Clin Nutr.

2009

Dietary intakes of ω-6 and ω-3 polyunsaturated fatty acids and the risk of breast cancer

Authors: Thi Chaj Gerber, M., Boutron-Ruault, M-C., Joulin, V., Lenoir, G., Berrino, F., et. al.

Publication Name: Int. J. Cancer:

Dietary n-6 PUFA deprivation for 15 weeks reduces arachidonic acid concentrations while increasing n-3 PUFA concentrations in organs of post-weaning male rats

Authors: Igarashi, M., Gao, F., Kim, H-W., Ma, K., Bell, J.M., Rapoport, S.I.

Publication Name: Biochimica et Biophysica Acta

Flaxseed gums and their absorption on whey protein-stabilized oil-in-water emulsions

Authors: Khallouﬁ, S. Corredig, M. Goff, D.H. Alexander, M.

Publication Name: Food Hydrocolloids

Fatty acids and lignans in unground whole ﬂaxseed and sesame seed are bioavailable but have minimal antioxidant and lipid-lowering effects in postmenopausal women

Authors: Coulman, K.D Liu, Z. Michaelides, J. Hum, W.Q. Thompson, L.U.

Publication Name: Mol. Nutr. Food Res.

Kinetics of the inhibition of renin and angiotensin I-converting enzyme by flaxseed protein hydrolysate fractions

Authors: Udenigwe, C.C. lin, Y.-S. Hou, W.-C. Aluko, R.E.

Publication Name: Journal of Functional Foods

Are all n-3 polyunsaturated fatty acids created equal?

Authors: Anderson, B.M. Ma, D.W.L.

Publication Name: Lipids in Health and Disease

Omega-3 fatty acids: a comprehensive review of their role in health and disease

Authors: Yashodhara, B.M. Umakanth, S. Pappachan, J.M. et. Al.

Publication Name: Postgrad Med. J.

Flaxseed oil prevents trans-10, cis-12-conjugated linoleic acid-induced insulin resistance in mice

Authors: Kelley, D.S. Vemuri, M. Adkins, Y. Gill, S.H.S. Fedor, D. Mackey, B.E.

Publication Name: British Journal of Nutrition

Effects of a flaxseed-derived lignan supplement on C-reactive protein, IL-6 and retinol-binding protein 4 in type 2 diabetic patients

Authors: Pan, A. Demark-Wahnefried, W. Ye, X. Yu, Z. Li, H. Qi, Q. Sun, J. et. al.

Publication Name: British Journal of Nutrition

Effect of ﬂaxseed gum on reduction of blood glucose and cholesterol in type 2 diabetic patients

Authors: Thakur, G. Mitra, A. Pal. K. Rousseau, D.

Publication Name: International Journal of Food Sciences and Nutrition

Quality of gluten-free supplemented cakes and biscuits

Authors: Gambus, H. Gambus, F.

Publication Name: International Journal of Food Science and Nutrition

The relation of a-linolenic acid to the risk of prostate cancer: a systematic review and meta-analysis.

Authors: Simon, J.A. Chen, Y-H. Bent, S.

Publication Name: Amer. J. Clin. Nutr.

Intervention with ﬂaxseed and borage oil supplements modulates skin condition in women

Authors: De Spirt, S. Stahl , W. Tronnier, H. Sies, H. Bejot, M. Maurette, J.-M. Heinrich, U.

Publication Name: British Journal of Nutrition

Alpha-linolenic acid supplementation and resistance training in older adults

Authors: Cornish, S.M. Chillibeck, P.D.

Publication Name: Appl. Physiol. Nutr. Metab.

A randomized controlled trial of the effects of flaxseed lignan complex on metabolic syndrome composite score and bone mineral in older adults

Authors: Cornish, S.M. Chillibeck, P.D. Paus-Jennsen, L. Biem, H.J. Khozani, T. Senanayake, V. Vatanparast, H. et. al.

Publication Name: Appl. Physiol. Nutr. Metab.

Alpha-linolenic acid and its conversion to longer chain n- 3 fatty acids: Beneﬁts for human health and a role in maintaining tissue n- 3 fatty acid levels

Authors: Barcelo-Coblijn, G. Murphy, E.J.

Publication Name: Progress in Lipid Research

Flaxseed Oil Supplementation Increases Plasma F1-Phytoprostanes in Healthy Men

Authors: Barden, A.E. Croft, K.D Durand, T. Guy, A. Mueller, M.J. Mori, T.A.

Publication Name: The Journal of Nutrition

Omega-3 fatty acids in the gravid pig uterus as affected by maternal supplementation with omega-3 fatty acids

Authors: Brazle, A.E. Johnson, B.J. Webel, S.K. Rathbun, T.J. Davis, D.L.

Publication Name: Journal of Animal Science

a-Linolenic acid supplementation and conversion to n-3 long-chain polyunsaturated fatty acids in humans

Authors: Brenna, J.T. Salem Jr., N. Sinclair, A.J. Cunnane, S.C

Publication Name: Prostaglandins, Leukotrienes and Essential Fatty Acids

Neuronal depletion of omega-3 fatty acids induces flax seed dietary self-selection in the rat

Authors: Dunlap, S. Heinrichs, S.C.

Publication Name: Brain Research

Quantitation of alpha-linolenic acid elongation to eicosapentaenoic and docosahexaenoic acid as affected by the ratio of n6/n3 fatty acids

Authors: Harnack, K. Andersen, G. Somoza, V.

Publication Name: Nutrition & Metabolism

Experimental and clinical research findings on the cardiovascular benefits of consuming flaxseed

Authors: Bassett, C.M.C. Rodriguez-Leyva, D. Pierce, G.N.

Publication Name: Appl. Physiol. Nutr. Metab.

Meta-analysis of the effects of ﬂaxseed interventions on blood lipids

Authors: Pan, A. Yu, D. Demark-Wahnefried, W. Franco, O.H. Lin, X.

Publication Name: Am. J. Clin. Nutr.

Bioavailability of alpha -linolenic acid from flaxseed diets as a function of the age of the subject

Authors: Patenaude, A. Rodriguez-Leyva, D. Edel, A.L. Dibrov, E. Dupasquier, C.M.C. Austria, J.A. Richard, M.N. et. al.

Publication Name: European Journal of Clinical Nutrition

Flaxseed and Cardiovascular Health

Authors: Prasad, K.

Publication Name: J. Cardiovasc. Pharmacol.

Designer oils low in n-6:n-3 fatty acid ratio beneﬁcially modiﬁes cardiovascular risks in mice

Authors: Riediger, N.D. Azordegan, N. Harris-Janz, S. Ma, D.W.L. Suh, M. Moghadasian, M.H.

Publication Name: Eur. J. Nutr.

Flaxseed Oil Attenuates Nonalcoholic Fatty Liver of Hyperlipidemic Hamsters

Authors: Yang, S.-F. Tseng, J.-K. Chang, Y.-Y. Chen, Y.-C.

Publication Name: J. Agric. Food Chem.

Dietary flaxseed prevents radiation-induced oxidative lung damage, inflammation and fibrosis in a mouse model of thoracic radiation injury

Authors: Lee, J.C. Krochak, R. Blouin, A. Kanterakis, S. Chatterjee, S. Arguiri, E. Vachani, A. et. al.

Publication Name: Cancer Biology & Therapy

Dietary intakes of α-linolenic and linoleic acids are inversely associated with serum C-reactive protein levels among Japanese men

Authors: Poudel-Tandukar, K. Nanri, A. Matsushita Y. Sasaki, S. Ohta M. Sato, M. Mizoue, T.

Publication Name: Nutrition Research

Meta-analyses of lignans and enterolignans in relation to breast cancer risk

Authors: Buck, K. Zaineddin, A.K. Vrieling, A. Linseisen, J. Chang-Claude, J.

Publication Name: Am. J. Clin. Nutr.

Flax lignans: new opportunities for functional foods

Authors: Muir, A.D.

Publication Name: Food Science and Technology Bulletin: Functional Foods

Flax Lignan Complex Slows Down the Progression of Atherosclerosis in Hyperlipidemic Rabbits

Authors: Prasad, K.

Publication Name: J. Cardiovasc. Pharmacol. Ther.

Phytosterols accumulation in the seeds of Linum usitatissimum L.

Authors: Herchi, W. Harrabi, S. Sebei, K. Rochut, S. Boukhchina, S. Pepe, C. Kallel, H.

Publication Name: Plant Physiology and Biochemistry

Effects of alpha-linolenic acid vs. docosahexaenoic acid supply on the distribution of fatty acids among the rat cardiac subcellular membranes after a short- or long-term dietary exposure

Authors: Brochot, A. Guinot, M. Auchere, D. Macaire, J.-P. Weill, P. Grynberg, A. Rousseau-Ralliard, D.

Publication Name: Nutrition & Metabolism

Red Blood Cell Membrane Alpha-linolenic Acid and the Risk of Sudden Cardiac Arrest

Authors: Lemaitre, R.N. King, I.B. Sotoodehnia, N. Rea, T.D. Raghunathan, T.E. Rice, K. Lumley, T. et.al.

Publication Name: Metabolism

Does genetic variation in the Δ6 -desaturase promoter modify the

Authors: Truong, H. DiBello, J.R. Ruiz-Narvaez, E. Kraft, P. Campos, H. Baylin, A.

Publication Name: Am. J. Clin. Nutr.

Subchronic Alpha Linolenic Acid Treatment Enhances Brain Plasticity and Exerts an Antidepressant Effect: A Versatile Potential Therapy for Stroke

Authors: Blondeau, N. Nguemeni, C. Debruyne, D.N. Piens, M. Wu, X. Pan, H. Hu, X.Z. Gandin, C. et al

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2008

Nutrition impacts the prevalence of peripheral arterial disease in the United States

Authors: Lane, J.S., Magno, C.P., Lane, K.T., Chan, T., Hoyt, D.B., Greenfield, S

Publication Name: J. Vasc. Surg.

Plasma fatty acid composition and incident heart failure in middle-aged adults: The Atherosclerosis Risk in Communities (ARIC) Study

Authors: Yamagishi, K., Nettleton, J.A., Folsom, A.R.

Publication Name: Am. Heart J.

Whole Body Synthesis-Secretion Rates of Long-Chain n-3 Polyunsaturated Fatty Acids from Circulating Unesterified α-Linolenic Acid in Unanesthetized Rats

Authors: Gao, F., Kiesewetter, D., Chang, L., Ma, K., Bell, J.M., Rapoport, S.I., Igarashi, M.

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Gender differences in rat erythrocyte and brain docosahexaenoic acid composition: Role of ovarian hormones and dietary omega-3 fatty acid composition

Authors: McNamara, R.K., Able, J., Jandacek, R., Rider, T., Tso, P.

Publication Name: Psychoneuroendocrinology

Effects of Dietary a-Linolenic Acid, Eicosapentaenoic Acid or Docosahexaenoic Acid on Parameters of Glucose Metabolism in Healthy Volunteers

Authors: Egert, S., Fobker, M., Andersen, G., Somoza, V., Erbersdobler, H.F., Wahrburg, U.

Publication Name: Ann. Nutr. Metab.

Dietary n-3 Polyunsaturated Fatty Acids Enhance Hormone Ablation Therapy in Androgen-Dependent Prostate Cancer

Authors: McEntee, M.F., Ziegler, C., Reel, D., Tomer, K., Shoieb, A., Ray,M., Li,X., et.al.

Publication Name: Am. J. Pathol.

The Evidence for Dietary Prevention and Treatment of Cardiovascular Disease

Authors: Van Horn, L., McCoin, M., Kris-Etherton, P.M., Burke, F., Carson, J.N.S., Champagne, C.M., Karmally, W., Sikand, G.

Publication Name: J Am Diet Assoc.

A possible role of prolyl oligopeptidase during Linum usitatissimum (flax) seed development

Authors: Gutierrez, L., Castelain, M., Verdeil, J-L., Conejero, G., Van Wuytswinkel, O.

Publication Name: Plant Biology (Stuttg.)

Glycemic index, glycemic load, and chronic disease risk a meta-analysis of observational studies

Authors: Barclay, A.W. Petocz, P., McMillan-Price, J., Flood, V.M., Prvan, T., Prvan, T., Brand-Miller, J.C.

Publication Name: Am J Clin Nutr

High dose flaxseed oil supplementation may affect fasting blood serum glucose management in human type 2 diabetics

Authors: Barre, D.E., Mizier-Barre, K.A., Griscti, O., Hafez, K.

Publication Name: J Oleo sci

Flaxseed and Cardiovascular Risk Factors: Results from a Double Blind, Randomized, Controlled Clinical Trial

Authors: Bloedon, L.T., Balikai, S., Chittams, J., Cunnane, S.C. Berlin, J.A., Rader, D.J., Szapary, P.O.

Publication Name: J Am Coll Nutr

Chemical composition and oxidative stability of flax, safflower and poppy seed and seed oils

Authors: Bozan, B., Temelli, F.

Publication Name: Bioresour. Technol.

Effect of estrogenic compounds (estrogen or phytoestrogens) combined with exercise on bone and muscle mass in older individuals

Authors: Chilibeck, P.D., Cornish, S.M.

Publication Name: Appl Physiol Nutr Metab

Mechanisms by which botanical lipids affect inflammatory disorders

Authors: Chilton, F.H., Rudel, L.L., Parks, J.S., Arm, J.P., Seeds, M.C.

Publication Name: Am J Clin Nutr

Flaxseed on cardiovascular disease markers in healthy menopausal women: a randomized, double-blind, placebo-controlled trial

Authors: Dodin, S., Cunnane, S.C., M�sse, B., Lemay, A., Jacques, H., Asselin, G., Tremblay-Mercier, J., et. al.

Publication Name: Nutrition

Metabolism of the Lignan Macromolecule into Enterolignans in the Gastrointestinal Lumen As Determined in the Simulator of the Human Intestinal

Authors: Eeckhaut, E., Struijs, K., Possemiers, S., Vincken, J-P., De Keukeleire, D., Verstraete, W.

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The Importance of the Omega-6/Omega-3 Fatty Acid Ratio in Cardiovascular Disease and Other Chronic Diseases

Authors: Simopoulos, A.P.

Publication Name: Exp. Biol. Med.

Chronic effects of a high-fat diet enriched with virgin olive oil and a low-fat diet enriched with a-linolenic acid on postprandial endothelial function in healthy men

Authors: Fuentes, F., L P Jim Mar G Fern et.al.

Publication Name: Br. J. Nutr.

The effect of a lignan complex isolated from flaxseed on inflammation markers in healthy postmenopausal women

Authors: Hallund, J., Tetens, I., Bügel, S., Tholstrup, T., Bruun, J.M.

Publication Name: Nutri, Metab & Cardiovascular Dis

A Comparison of Fish Oil, Flaxseed Oil and Hempseed Oil Supplementation on Selected Parameters of Cardiovascular Health in Healthy Volunteers

Authors: Kaul, N., Kreml, R., Austria, J.A., Richard, M.N., Edel, A.L., Dibrov, E., Hirono, S. et. al

Publication Name: J Am Coll Nutr

n-3 Fatty Acids: Food or Supplements?

Authors: Kris-Etherton, P.M., Hill, A.M.

Publication Name: J Am Dietetic Assoc

Plasma Enterolignan Concentrations and Colorectal Cancer Risk in a Nested Case-Control Study

Authors: Kuijsten, A., Hollman, P.C.H., Boshuizen, H.C., Buijsman, M.N.C.P., vant Veer, P., Kok, F.J., Arts, I.C.W., Bas Bueno-de-Mesquita, H.

Publication Name: Am J Epidemiology

Effects of grain processing and dietary lipid source on performance, carcass characteristics, plasma fatty acids, and sensory properties of steaks from finishing cattle

Authors: LaBrune, H.J., Reinhardt, C.D., Dikeman, M.E.. Drouillard, J.S.

Publication Name: J Anim Sci

Dietary omega 3 fatty acids and the developing brain

Authors: Innis, S.M.

Publication Name: Brain Research

[Interest of lignans in prevention and treatment of cancers.]

Authors: Lamblin, F., Hano, C., Fliniaux, O., Mesnard, F., Fliniaux, M.A., Lainé, E.

Publication Name: Med Sci (Paris)

Dietary flaxseed enhances antioxidant defenses and is protective in a mouse model of lung ischemia-reperfusion injury

Authors: Lee, J.C., Bhora, F., Sun, J., Cheng, G., Arguiri, E., Solomides, C.C., Chatterjee, S., Christofidou-Solomidou, M.

Publication Name: Am J Physiol Lung Cell Mol Physiol

Enterolactone restricts the proliferation of the LNCaP human prostate cancer cell line in vitro

Authors: McCann, M.J., Gill, C.I.R., Linton, T., Berrar, D., McGlynn, H., Rowland, I.R.

Publication Name: Mol. Nutr. Food Res.

High dietary ω-6 fatty acids contribute to reduced docosahexaenoic acid in the developing brain and inhibit secondary neurite growth

Authors: Novak, E.M., Dyer, R.A., Innis, S.M.

Publication Name: Brain Research

A comparison of the effects of fish oil and flaxseed oil on cardiac allograft chronic rejection in rats.

Authors: Othman, R.A. Suh,M., Fischer, G., Azordegan, N., Riediger, N., Le, K., Jassal, D.S., Moghadasian, M.H.

Publication Name: Am. J. Physiol. Heart Circ. Physiol.

Dietary n – 6 and n – 3 polyunsaturated fatty acids: From biochemistry to clinical implications in cardiovascular prevention

Authors: Russo, G.L. Biochem. Pharmacol.

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Interaction between a-Linolenic Acid-Enriched Oil and ACE Inhibitor Concerning the Decrease in Blood Pressure in SHR

Authors: Matsuo, T., Kanako, Y.

Publication Name: J. Oleo Sci.

Effects of a Flaxseed-Derived Lignan Supplement in Type 2 Diabetic Patients: A Randomized, Double-Blind, Cross-Over Trial

Authors: Pan, A., Sun, J., Chen, Y., Ye, X., Li, H., Yu, Z., Wang, Y., et. al.

Publication Name: PLoS ONE

a -Linolenic Acid and Risk of Nonfatal Acute Myocardial Infarction

Authors: Campos, H., Baylin, A., Willett, W.C.

Publication Name: Circulation

Cardiovascular Risk and a-Linolenic Acid: Can Costa Rica Clarify?

Authors: Harris, W.S.

Publication Name: Circulation

Regression of hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglucoside isolated from flaxseed

Authors: Prasad, K.

Publication Name: Atherosclerosis

Topical Omega-3 and Omega-6 Fatty Acids for Treatment of Dry Eye

Authors: Rashid, S. Jin, Y. Ecoiffier, T. Barabino, S. Schaumberg, D.A. Dana, M.R.

Publication Name: Arch. Ophthalmol.

Low n-6:n-3 fatty acid ratio, with fish- or flaxseed oil, in a high fat diet improves plasma lipids and beneficially alters tissue fatty acid composition in mice

Authors: Riediger, N.D., Othman, R., Fitz, E., Pierce, G.N., Suh, M., Moghadasian, M.H.

Publication Name: Eur. J. Nutr.

Development and pilot testing of an omega-3 fatty acid food frequency questionnaire

Authors: Ritter-Gooder, P.K., Lewis, N.M., Barber-Heidal, K., Waltz-Hill, M.

Publication Name: J. Food Composition & Analysis

Effect of two doses of a mixture of soluble fibres on body weight and metabolic variables in overweight or obese patients: a randomised trial

Authors: Salas-Salvadó, J., Farrés, X., Luque, X., Narejos, S., Borrell, M., Basora, J., Anguera, A., et al.

Publication Name: Br. J.Nutr.

Flaxseed lignan attenuates high-fat diet-induced fat accumulation and induces adiponectin expression in mice

Authors: Fukumitsu, S., Aida, K., Ueno, N., Ozawa, S., Takahashi, Y., Kobori, M.

Publication Name: Br. J. Nutr.

Update on alpha-linolenic acid

Authors: Stark, A.H., Crawford, M.A., Reifen, R.

Publication Name: Nutrition Reviews

Relationship of Polyunsaturated Fatty Acid Intake to Peripheral Neuropathy Among Adults With Diabetes in the National Health and Nutrition Examination Survey (NHANES) 1999 2004

Authors: Tao, M., McDowell, M.A., Saydah, S.H., Eberhardt, M.S.

Publication Name: Diabetes Care

Flaxseed oil and fish-oil capsule consumption alters human red blood cell n3 fatty acid composition: a multiple-dosing trial comparing 2 sources of n3 fatty acid

Authors: Barcel-Coblijn, G., Murphy, E.J., Othman, R., Moghadasian, M.H., Moghadasian, M.H., Friel, J.K.

Publication Name: Am. J. Clin. Nutr.

Effect of flaxseed gum addition on rheological properties of native maize starch

Authors: Wang, Y., Wang, L-J., Li, D., �zkan, N., Chen, X.D., Mao, Z-H.

Publication Name: J. Food Engineering

Rapid declines in coronary heart disease mortality in Eastern Europe are associated with increased consumption of oils rich in alpha-linolenic acid

Authors: Zatonski, W., Campos, H., Willett. W.

Publication Name: Eur. J. Epidemiol.

Dietary flaxseed lignan extract lowers plasma cholesterol and glucose concentrations in hypercholesterolaemic subjects

Authors: Zhang, W., Wang, X., Liu, Y., Tian, H., Flickinger, B., Empie, M.W., Sun, S.Z.

Publication Name: Br. J. Nutr.

Effects of Dietary Flaxseed Lignan Extract on Symptoms of Benign Prostatic Hyperplasia

Authors: Zhang, W., Wang, X., Liu, Y., Tian, H., Flickinger, B., Empie, M.W., Sun, S.Z.

Publication Name: J. Med. Food

Omega-3 PUFA: Good or bad for prostate cancer?

Authors: Brouwer, I.A.

Publication Name: Prostaglandins, Leukotrienes & Essential Fatty Acids

Fungistatis activity of flaxseed in potato dextrose agar and a fresh noodle system

Authors: Xu, Y. Hall, C. Wolf-Hall, C. Manthey, F.

Publication Name: International Journal of Food microbiology

Effect of Dietary Flaxseed on Serum Levels of Estrogens and Androgens in Postmenopausal Women

Authors: Sturgeon, S.R. Heersink, J.L.

Publication Name: Nutrition and Cancer

Novel Rhamnogalacturonan I and Arabinoxylan Polysaccharides of Flax Seed Mucilage

Authors: Naran, R. Chen, G. Carpita, N.C.

Publication Name: Plant Physiology

Antifungal Activity Stability of Flaxseed Protein Extract Using Response Surface Methodology

Authors: Xu, Y. Hall , C. Wolf-Hall, C.

Publication Name: Journal of Food Science

Optimization of the -3 extraction as a functional food from flaxseed

Authors: Hassan-Zadeh, A. Sahari, M.A. Barzegar, M.

Publication Name: International Journal of Food Science and Nutrition

Changes in biomarkers of estrogen receptor and growth factor signaling

Authors: Power, K.A. Chen, J.M. Saarinen, N.M. Thompson, L.U.

Publication Name: J. Steroid Biochem. Molec. Biol.

Overcoming challenges in designing and implementing a phase II randomized controlled trial using a presurgical model to test a dietary intervention in prostate cancer.

Authors: Demark-Wahnefried, W. George, S.L. Switzer, B.R. Snyder, D.C. Madden, J.F. Polascik, T.J. Ruffin, M.T. Vollmer, R.T.

Publication Name: Clinical Trials

How relevant is the ratio of dietary n-6 to n-3 polyunsaturated fatty acids to cardiovascular disease risk Evidence from the OPTILIP study

Authors: Griffin, B.A.

Publication Name: Current Opinion in Lipidology

Bioavailability of Alpha-Linolenic Acid in Subjects after Ingestion of Three Different Forms of Flaxseed

Authors: Austria, J.A. Richard, M.N. Chahine, M.N. Edel, A.L. Malcolmson, L.J. Dupasquier, C.M.C. Pierce, G.N.

Publication Name: Journal of the American College of Nutrition

FADS genotypes and desaturase activity estimated by the ratio of arachidonic acid to linoleic acid are associated with inflammation and coronary artery disease

Authors: Martinelli, N. Girelli, D. Malerba, G. Guarini, P. Illig, T. Trabetti, E. Sandri, M. et.al.

Publication Name: Am. J. Clin. Nutr.

Flaxseed Reduces Total and LDL Cholesterol Concentrations in Native American Postmenopausal Women

Authors: Patade, A. Devareddy, L. Lucas, E.A. Korlagunta, K. Daggy, B.P. Arjmandi, B.H.

Publication Name: Journal of Women's Health

Dietary lignans and postmenopausal breast cancer risk by oestrogen receptor status: a prospective cohort study of Swedish women

Authors: Suzuki, R. Rylander-Rudqvist, T. Saji, S. Bergkvist, L. Adlercreutz, H. Wolk, A.

Publication Name: British Journal of Cancer

The effect of dietary oleic, linoleic, and linolenic acids on fat oxidation and energy expenditure in healthy men

Authors: Jones, P.J.H. Jew, S. AbuMweis, S.

Publication Name: Metabolism Clinical and Experimental

Changing ratios of omega-6 to omega-3 fatty acids can differentially modulate polychlorinated biphenyl

Authors: Wang, L. Reiterer, G. Toborek, M. Hennig, B.

Publication Name: Chemico-Biological Interactions

Egg Fortification with n-3 Polyunsaturated Fatty Acids (PUFA): Nutritional Benefits versus High n-6 PUFA Western Diets, and Consumer Acceptance.

Authors: Shapira, N. Weill, P. Loewenbach, R.

Publication Name: IMAJ.

2007

Late Dietary Intervention Limits Benefits of Soy Protein or Flax Oil in Experimental Polycystic Kidney Disease

Authors: Sankaran, D., Bankovic-Calic, N., Cahill, L., Peng, C.Y-C., Ogborn, M.R., Aukema, H.M.

Publication Name: Nephron. Exp. Nephrol.

Inflammatory markers are not altered by an eight week dietary a-linolenic acid intervention in healthy abdominally obese adult males and females

Authors: Nelson, T.L., Stevens, J.R., Hickey, M.S.

Publication Name: Cytokine

Omega-3 Polyunsaturated Fatty Acid Intake and Islet Autoimmunity in Children at Increased Risk for Type 1 Diabetes

Authors: Norris, J.M., Yin, X., Lamb, M.M., Barriga, K., Seifert, J., Hoffman, M., Orton, H.D., et. al.

Publication Name: JAMA

Systemic Inflammation in Morbidly Obese Subjects:Response to Oral Supplementation with Alpha-Linolenic Acid

Authors: Faintuch, J., Horie, L.M., Barbeiro, H.V., Barbeiro, D.F., Soriano, F.G., Ishida, R.K., Cecconello, I.

Publication Name: Obesity Surgery

Hepatic Steatosis and Increased Adiposity in Mice Consuming Rapidly vs. Slowly Absorbed Carbohydrate

Authors: Scribner, K.B., Pawlak, D.B., Ludwig, A.S.

Publication Name: Obesity

Secoisolariciresinol Diglucoside: Relevance to Angiogenesis and Cardioprotection against Ischemia-Reperfusion Injury

Authors: Penumathsa, S.V., Koneru, S., Thirunavukkarasu, M., Zhan, L., Prasad, K., Maulik, N.

Publication Name: J. Pharmacol. Exp. Ther.

Feeding flaxseed oil but not secoisolariciresinol diglucoside results in higher bone mass in healthy rats and rats with kidney disease

Authors: Weiler, H.A., Kovacs,H., Nitschmann, E., Bankovic-Calic, N., Aukema, H., Ogborn, M.

Publication Name: Prostaglandins Leukot. Essent. Fatty Acids

Dietary supplementation with flaxseed oil lowers blood pressure in dyslipidaemic patients

Authors: Paschos, G.K., Magkos, F., Panagiotakos, D.B., Votteas, V., Zampelas, A.

Publication Name: Eur. J. Clin. Nutr.

Growth performance, gastrointestinal microbial activity and nutrient digestibility in early weaned pigs fed diets containing flaxseed and carbohydrase enzyme

Authors: Kiarie, E., Nyachoti, C.M., Slominski, B.A., Blank, G.

Publication Name: J. Anim. Sci.

Effects of dietary supplementation with flax during prepuberty on fatty acid profile, mammogenesis, and bone resorption in gilts

Authors: Farmer, C., Petit, H.V., Weiler, H., Capuco, A.V.

Publication Name: J. Anim. Sci.

Effects of flaxseed oil supplementation on plasma adiponectin levels in dyslipidemic men

Authors: Paschos, G.K., Zampelas, A., Panagiotakos, D.B., Katsiougiannis, S., Griffin, B.A., Votteas, V., Skopouli, F.N.

Publication Name: Eur. J. Nutr.

The human peripheral blood mononuclear cell proteome responds to a dietary flaxseed-intervention and proteins identified suggest a protective effect in atherosclerosis

Authors: Fuchs, D., Piller, R., Linseisen, J., Daniel, H., Wenzel, U.

Publication Name: Proteomics

Adiponectin levels are reduced, independent of polymorphisms in the adiponectin gene, after supplementation with α-linolenic acid among healthy adults

Authors: Nelson, T.L., Stevens, J.R., Hickey. M.S.

Publication Name: Metab. Clin. Exp.

Dietary supplementation of obese children with 1000 mg alpha-linolenic acid per day: a placebo-controlled double blind study.

Authors: Lohner, S., Marosvolgyi, T., Burus, I., Schmidt, J., Molnar, D., Decsi, T.

Publication Name: Orv. Hetil.

Microwave-assisted Extraction of the Main Phenolic Compounds in Flaxseed

Authors: Beejmohun, V., Fliniaux, O., Grand, E., Lamblin, F., Bensaddek, L., Christen, P., Kovensky, J., et. Al

Publication Name: Phytochem. Anal.

Antioxidant activities of the flaxseed lignan secoisolariciresinol diglucoside, its aglycone ecoisolariciresinol and the mammalian lignans enterodiol and enterolactone in vitro

Authors: Hu, C., Yuan, Y.V., Kitts. D.D.

Publication Name: Food Chem. Toxicol.

Effectiveness of Oils Rich in Linoleic and Linolenic Acids to Enhance Conjugated Linoleic Acid in Milk from Dairy Cows

Authors: Bu, D.P., Wang, J.Q., Dhiman, T.R., Liu, S.J.

Publication Name: J. Dairy Sci.

Flaxseed and Its Lignans Inhibit Estradiol-Induced Growth, Angiogenesis, and Secretion of Vascular Endothelial Growth Factor in Human Breast Cancer Xenografts In vivo

Authors: Jungestr?m, M.B., Thompson, L.U., Dabrosin, C.

Publication Name: Clin. Cancer Res.

Can the combination of flaxseed and its lignans with soy and its isoflavones reduce the growth stimulatory effect of soy and its isoflavones on established breast cancer?

Authors: Power, K.A., Thompson, L.U.

Publication Name: Mol. Nutr. Food Res.

Influence of prebiotics and antioxidants in bread on the immune system, antioxidative status and antioxidative capacity in male smokers and non-smokers

Authors: Seidel, C., Boehm, V., Vogelsang, H.,Wagner, A., Persin, C., Glei, M., Pool-Zobel, B.L., Jahreis, G.

Publication Name: Br. J. Nutr.

Lignan-rich sesame seed negates the tumor-inhibitory effect of tamoxifen but maintains bone health in a postmenopausal athymic mouse model with estrogen-responsive breast tumors.

Authors: Sacco, S.M., Chen, J., Power, K.A., Ward, W.E., Thompson, L.U.

Publication Name: Menopause.

Maternal flaxseed diet during pregnancy or lactation increases female rat offspring

Authors: Khan, G., Penttinen, P., Cabanes, A., Foxworth, A., Chezek, A., Mastropole, K., Yu, B., et al.

Publication Name: Reprod. Toxicol.

Flaxseed Alone or in Combination with Tamoxifen Inhibits MCF-7 Breast Tumor Growth in Ovariectomized Athymic Mice with High Circulating Levels of Estrogen

Authors: Chen, J., Power. K.A., Mann, J., Cheng, A., Thompson, L.U.

Publication Name: Exp. Biol. Med.

Interaction of Sesame Seed and Tamoxifen on Tumor Growth and Bone Health in Athymic Mice

Authors: Sacco, S.M., Power, K.A., Chen, J., Ward, W.E., Thompson, L.U.

Publication Name: Exp. Biol. Med.

Dietary Flaxseed Interaction With Tamoxifen Induced Tumor Regression in Athymic Mice With MCF-7 Xenografts by Downregulating the Expression of Estrogen Related Gene Products and Signal Transduction Pathways

Authors: Chen, J., Power, K.A., Mann, J., Cheng, A., Thompson, L.U.

Publication Name: Nutr. Cancer

Feeding enriched omega-3 fatty acid beef to rats increases omega-3 fatty acid content of heart and liver membranes and decreases serum vascular cell adhesion molecule-1 and cholesterol levels.

Authors: Medeiros, D.M., Hampton, M., Kurtzer, K., Parelman, M., Al-Tamimi, E., Drouillard, J.S.

Publication Name: Nutr. Res.

101 Tips on Nutrition for People With Diabetes (second edition)

Authors: Leontos, C.

Publication Name: The Diabetes Educator

The effect of altering the 20:5n-3 and 22:6n-3 content of a meal on the postprandial incorporation of n-3 polyunsaturated fatty acids into plasma triacylglycerol and non-esterified fatty acids in humans.

Authors: Burdge, G.C., Sala-Vila, A., West, A.L., Robson, H.J., Le Fevre, L.W., Powell, J., Calder, P.C.

Publication Name: Prostaglandins Leukot. Essent. Fatty Acids.

Effects of Flavonoids and Phenolic Acids on the Inhibition of Adipogenesis in 3T3-L1 Adipocytes

Authors: Hsu, C-L., . Yen, G-C

Publication Name: J. Agric. Food Chem.

Effect of a high-fiber diet vs a fiber supplemented diet on C-reactive protein level.

Authors: King, D.E., Egan, B.M., Woolson, R.F., et al.

Publication Name: Arch. Intern. Med.

Dietary flavonoid intake and breast cancer risk among women on Long Island.

Authors: Fink, B.N., Steck, S.E., Wolff, M.S., et al.

Publication Name: Am. J. Epidemiol.

Alpha-linolenic acid and fish oil n3 fatty acids and cardiovascular disease risk. Letter to the editor.

Authors: Vos, E., et al.

Publication Name: Amer. J. Clin. Nutr.

Alpha-linolenic acid and fish oil n3 fatty acids and cardiovascular disease risk. Reply to E Vos et al.

Authors: Lau, J., et al.

Publication Name: Amer. J. Clin. Nutr.

Postprandial effect of n-3 polyunsaturated fatty acids on apolipoprotein B-containing lipoproteins and vascular reactivity in type-2 diabetes.

Authors: Hilpert, K.F., West, S.G., Kris-Etherton, P.M., et al.

Publication Name: Amer. J. Clin. Nutr.

Decreasing linoleic acid with constant alpha-linolenic acid in dietary fats increases (n-3) eicosapentaenoic acid in plasma phospholipids in healthy men.

Authors: Liou, Y.A., King, D.J., Zibrik, D., Innis, S.M.

Publication Name: J. Nutr.

An increase in dietary n-3 fatty acids decreases a marker of bone resorption in humans.

Authors: Griel, A.E., Kris-Etherton, P.M., Hilpert, K.F., et al.

Publication Name: J. Nutr.

Dietary Lignan Intake and Postmenopausal Breast Cancer Risk by Estrogen and Progesterone

Authors: Touillaud , M.S., Thi?baut, A.C.M., Fournier, A., Niravong, M., Boutron-Ruault, M.C., Clavel-Chapelon, F.

Publication Name: J. Natl. Cancer Inst.

Association between dietary fiber and endometrial cancer: a dose-response meta-analysis

Authors: Bandera, E.V., Kushi, L.H., Moore, D.F., Gifkins, D.M., McCullough, M.L.

Publication Name: Am J Clin Nutr.

Dietary fibre and risk of breast cancer in the UK Womens Cohort Study.

Authors: Cade, JE Burley, VJ Greenwood, DC

Publication Name: Int. J. Epidemiol.

Dietary patterns and risk of dementia: The Three-City Cohort study

Authors: Barberger-Gateau, P. Raffaitin, C. Letenneaur, L. Berr, C. Tzourio, C. Dartigues, J.F. Alp�rovitch, A.

Publication Name: Neurology

Nutraceuticals: Facts and fiction

Authors: Esp?n, J.C., Garc?a-Conesa, M.T., Tom?s-Barber?n, F.A.

Publication Name: Phytochemistry

Move Onward, Press Forward, and Take a Deep Breath: Can Lifestyle Interventions Improve the Quality of Life of Women With Breast Cancer, and How Can We Be Sure?

Authors: Demark-Wahnefried, W.

Publication Name: J. Clin Oncol.

Dietary alpha-linolenic acid inhibits proinflammatory cytokine production by peripheral blood mononuclear cells in hypercholesterolemic subjects.

Authors: Zhao, G., Etherton, T.D., Martin, K.R., et al.

Publication Name: Amer. J. Clin. Nutr.

Dietary Fiber, Lung Function, and Chronic Obstructive Pulmonary Disease in the Atherosclerosis Risk in Communities Study.

Authors: Kan, H., Stevens, J., Heiss, G., Rose, K.M., London, S.J.

Publication Name: Am. J. Epidemiol.

Flax seed oil and flax seed meal reduce the formation of aberrant crypt foci (ACF) in azoxymethane-induced colon cancer in Fisher 344 male rats.

Authors: Williams, D., Verghese, M., Walker, L.T., Boateng, J., Shackelford, L., Chawan, L.B.

Publication Name: Food Chem.Toxicol.

Effects of a Flaxseed-Derived Lignan Supplement in Type 2 Diabetic Patients: A Randomized, Double-Blind, Cross-Over Trial.

Authors: Pan, A., Sun, J., Chen, Y., Ye, X., Li, H., Yu, Z., Wang, Y., et.al.

Publication Name: PLoS ONE.

Dietary Canola Oil Suppressed Growth of Implanted MDA-MB 231Human Breast Tumors in Nude Mice.

Authors: Hardman, W.E.

Publication Name: Nutr. & Cancer

Dietary omega-3 fatty acids for women.

Authors: Bourre, J.M.

Publication Name: Biomed. Pharmacother.

Influence of three rapeseed oil-rich diets, fortified with α-linolenic acid, eicosapentaenoic acid or docosahexaenoic acid on the composition and

Authors: Egert, S., Somoza, V., Kannenberg, F., Fobker, M., Krome, K., Erbersdobler, H.F., Wahrburg, U.

Publication Name: Eur. J. Clin. Nutr.

Moderate Dietary Intake of Myristic and Alpha-Linolenic Acids Increases Lecithin-Cholesterol Acyltransferase Activity in Humans.

Authors: Vaysse-Boué, C., Dabadie, H., Peuchant, E., Le Ruyet, P., Mendy, F., Gin, H., Combe, N.

Publication Name: Lipids

Effect of dietary lard containing higher α-linolenic acid on plasma triacylglycerol in rats.

Authors: Murano, Y., Funabashi, T., Sekine, S., Aoyama, T., Takeuchi, H.

Publication Name: J. Oleo Sci.

2149 solin (low linolenic flax).

Authors: Dribnenki, J.C.P., McEachern, S.F., Chen, Y., Green, A.G., Rashid, K.Y.

Publication Name: Can. J. Plant Sci.

Cadmium-induced alterations of the structural features of pectins in Xax hypocotyl

Authors: Douchiche, O., Rihouey, C., Schaumann, A., Driouich, A., Morvan, C.

Publication Name: Planta

Lignans from Linum species of sections Syllinum and Linum

Authors: Konuklugil, B., Ionkova, I., Vasilev, N., Schmidt, T.J., Windhövel, J., Fuss, E., Alfermann, A.W.

Publication Name: Natural Product Research

The use of the phosphomannose isomerase gene as alternative selectable marker for Agrobacterium-mediated transformation of flax (Linum usitatissimum)

Authors: Lamblin, F., Aimé, A., Hano, C., Roussy, I., Domon, J-M., Van Droogenbroeck, B., Lainé, E.

Publication Name: Plant Cell Rep

Synthesis, characterization, antibacterial and corrosion protective properties of epoxies, epoxy-polyols and epoxy-polyurethane coatings from linseed and Pongamia glabra seed oils

Authors: Sharmin, E., Ashraf, S.M., Ahmad, S.

Publication Name: Int. J. Biol. Macromolecules

In vivo 13C NMR determines metabolic fluxes and steady state in linseed embryos

Authors: Troufflard, S., Roscher, A., Thomasset, B., Barbotin, J-N., Rawsthorne, S., Portais, J-C.

Publication Name: Phytochemistry

Lignans and Human Health

Authors: Adlercreutz, H.

Publication Name: Critical Reviews in Clinical Laboratory Sciences

Planting a Seed: Can Flax Prevent Diabetes?

Authors: D?arrigo, T.

Publication Name: Diabetes Forecast

Dietary flaxseed inhibits atherosclerosis in the LDL receptor-deficient mouse in part through antiproliferative and anti-inflammatory actions

Authors: Dupasquier, C.M.C., Dibrov, E., Kneesh, A.L., Cheung, P.K.M., Lee, K.G.Y., Alexander, H.K., Yeganeh, B.K., et. al.

Publication Name: Am J Physiol Heart Circ Physiol

The effects of dietary flaxseed supplementation on lipid metabolism in streptozotocin-induced diabetic hamsters

Authors: Haliga, R., Mocanu, V., Oboroceanu, T., Stitt, P.A., Luca, V.C.

Publication Name: Rev Med Chir Soc Med Nat Iasi.

Integral bread development with soybean, chia, linseed, and folic acid as a functional food for woman

Authors: Justo, M.B., Alfaro, A.D., Aguilar, E.C., Wrobel, K., Wrobel, K., Guzmán, G.A., Sierra, Z.G.

Publication Name: Arch Latinoam Nutr

Short Communication Effect of flaxseed and wheat flour blends on dough rheology and bread quality

Authors: Koca, A.F., Anil, M.

Publication Name: J Sci Food Agric

Dietary Linolenic Acid Intake Is Positively Associated with Five-Year Change in Eye Lens Nuclear Density

Authors: Lu, M. Taylor, A. Chylack, Jr., L.T. Rogers, G. Hankinson, S.E. Willett, W.C. Paul F. Jacques, P.F.

Publication Name: Journal of the American College of Nutrition

Flaxseed Reduces Plasma Cholesterol Levels in Hypercholesterolemic Mouse Models

Authors: Pellizzon, M.A., Billheimer, J.T. Bloedon, L.T., Szapary, P.O., Rader, D.J.

Publication Name: J Am Coll Nutr

Flaxseed and Soy Protein Isolate, Alone and in Combination, Differ in their Effect on Bone Mass, Biomechanical Strength, and Uterus in Ovariectomized Nude Mice with MCF-7 Human Breast Tumor Xenografts

Authors: Power, K.A., Ward, W.E., Chen, J.M., Saarinen, N.M., Thompson, L.U.

Publication Name: J. Toxicol. & Environ. Health, Part A

Sensitivity of fetus and pups to excess levels of maternal intakes of alpha linolenic acid at marginal protein levels in Wistar rats

Authors: Rao, S.S., Kale, A.A., Joshi, S.R., Mahadik, S.P.

Publication Name: Reproductive Toxicology

Choice of oils for essential fat supplements can enhance production of abnormal metabolites in fat oxidation disorders

Authors: Roe, C.R., Roe, D.S., Wallace, M., Garritson, B.

Publication Name: Molecular Genetics & Metabolism

Benefits and Side Effects of Different Vegetable Oil Vectors on Apoptosis, Oxidative Stress, and P2X7 Cell Death Receptor Activation

Authors: Said, T., Dutot, M., Christon, R., Beaudeux, J-L., Martin, C., Warnet, J-M., Rat, P.

Publication Name: Invest. Ophthalmol. Vis. Sci.

Lowering Systemis Blood Pressure and Increases in Vasodilator Levels in SHR with oral a-Linolenic Acid Administration

Authors: Sekine, S., Sasanuki, S., Aoyama, T., Takeuchi, H.,

Publication Name: J. Oleo Sci.

Regulation of zinc transporters by dietary flaxseed lignan in human breast cancer xenografts

Authors: Zhang. L-Y., Wang, W-L., Sun, D-X., Liu, X-X., Hu, X-Y., Kong, F.

Publication Name: Mol. Biol. Rep.

Pilot Evaluation of Flaxseed for the Management of Hot Flashes

Authors: Pruthi, S. Thompson, S.L. Novotny, P.J. Barton, D.L. Kottschade, L.A. Tan, A,D. Sloan, J.A. Loprinzi, C.L.

Publication Name: Journal of the Society for Integrative Oncology

Extremely limited synthesis of long chain polyunsaturates in adults: implications for their dietary essentiality and use as supplements

Authors: Plourde, M. Cunnane, S.C

Publication Name: Appl. Physiol. Nutr. Metab.

Brain metabolism of nutritionally essential polyunsaturated fatty acids depends on both the diet and the liver

Authors: Rapoport , S.I. Rao, J.S. Igarashi, M.

Publication Name: Prostaglandins, Leukotrienes and Essential Fatty Acids

alpha-Linolenic acid, Δ6-desaturase gene polymorphism, and the risk of nonfatal myocardial infarction 1� 3

Authors: Baylin, A. Ruiz-Narvaez, E. Kraft, P. Campos, H.

Publication Name: Am. J. Clin. Nutr.

Food Omega-3 Fatty Acid Intake of Individuals (Total, Linolenic Acid, Long-Chain) and Their Blood Pressure. INTERMAP Study

Authors: Ueshima, H. Stamler, J. Elliott, P. Chan, Q. Brown, I.J. Carnethon, M.R. Daviglus, M.L. et.al.

Publication Name: Hypertension

Anti-inflammatory Effect of α -Linolenic Acid and Its Mode of Action through the Inhibition of Nitric Oxide Production and Inducible Nitric Oxide Synthase Gene Expression via NF-қB and Mitogen-Activated Protein Kinase Pathways

Authors: Ren. J. Chung, S.H.

Publication Name: J. Agric. Food Chem.

Review: A defect in the activity of Δ6 and Δ5 desaturases may be a factor in the initiation and progression of atherosclerosis

Authors: Das, U.N.

Publication Name: Prostaglandins, Leukotrienes and Essential Fatty Acids

Extraction of lignans, proteins and carbohydrates from flaxseed meal with pressurized low polarity water.

Authors: Ho, C.H.L. Cacace, J.E. Mazza, G.

Publication Name: LWT

2006

Conception rate and reproductive function of dairy cows fed different fat sources

Authors: Petit, H.V., Twagiramungu, T.

Publication Name: Theriogenology

The Use of Enzyme Technology for Improved Energy Utilization from Full-Fat Oilseeds. Part II: Flaxseed

Authors: Slominski, B.A., Meng, X., Campbell, L.D., Guenter, W., Jones, O.

Publication Name: Poultry Science

Antioxidant Potentials of Flaxseed by in Vivo Model

Authors: Rajesha, J., Murthy, K.N.C., Kumar, M.K., Madhusudhan, B., Ravishankar, G.A.

Publication Name: J. Agric. Food Chem.

Beneficial effects of alpha linolenic acid rich flaxseed oil on growth performance and hepatic cholesterol metabolism in high fat diet fed rats

Authors: Vijaimohan, K., Jainu, M., Sabitha, K.E., Subramaniyam, S., Anandhan, C., Devi, C.S.S.

Publication Name: Life Sciences

Incorporation and Clearance of Omega-3 Fatty Acids in Erythrocyte Membranes and Plasma

Authors: Cao, J., Schwichtenberg, K.A., Hanson, N.Q., Tsai, M.Y.

Publication Name: Clin. Chem.

Effects of hempseed and flaxseed oils on the profile of serum lipids, serum total and lipoprotein lipid concentrations and haemostatic factors

Authors: Schwab, U.S., Callaway, J.C., Erkkil?, A.T., Gynther, J., Uusitupa, M.,I.,J., J?rvinen, T.

Publication Name: Eur. J. Nutr.

Increasing the amount of n-3 fatty acid in meat from young Holstein bulls through nutrition

Authors: Mach, N., Devant, M., D?az, I., Font-Furnols, M., Oliver, M.A., Garc?a, J.A., Bach, A.

Publication Name: J. Anim. Sci.

Effect of processing flax in beef feedlot diets on performance, carcass characteristics, and trained sensory panel ratings

Authors: Maddock, T.D., Bauer, M.L., Koch, K.B., Anderson, V.L., Maddock, R.J., Barcel? -Coblijn,G., Murphy, E.J., Lardy, G.P.

Publication Name: J. Anim. Sci.

Sesamin Is One of the Major Precursors of Mammalian Lignans in Sesame Seed (Sesamum indicum) as Observed In Vitro and in Rats

Authors: Liu, Z., Saarinen, M.N., Thompson, L.U.

Publication Name: J. Nutr.

Flaxseed and its components reduce metastasis after surgical excision of solid human breast tumor in nude mice

Authors: Chen, J., Wang, L., Thompson, L.U.

Publication Name: Cancer Letters

Effects of Flaxseed Derivatives in Experimental Polycystic Kidney Disease Vary with Animal Gender

Authors: Ogborn,M.R., Nitschmann, E., Bankovic-Calic, N., Weiler, H.A., Aukema, H.M.

Publication Name: Lipids

Bovine Muscle n-3 Fatty Acid Content Is Increased with Flaxseed Feeding

Authors: Kronberg, S.L., Barcel?-Coblijn, G., Shin, J., Lee, K., Murphy, E.J.

Publication Name: Lipids

Effect of cationic flaxseed protein hydrolysate fractions on the in vitro structure and activity of calmodulin-dependent endothelial nitric oxide synthase

Authors: Omoni, A.O., Aluko, R.E.

Publication Name: Mol. Nutr. Food Res.

A randomized controlled trial of the effect of dietary soy and flaxseed muffins on quality of life and hot flashes during menopause

Authors: Lewis, J.E., Nickell, L.A., Thompson, L.U., Szalai, J.P., Kiss, A., Hilditch, J.R.

Publication Name: Menopause.

Mammalian lignans enterolactone and enterodiol, alone and in combination with the isoflavone genistein, do not promote the growth of MCF-7 xenografts in ovariectomized athymic nude mice

Authors: Power, K.A., Saarinen, N.M., Chen J., Thompson, L.U.

Publication Name: Int. J. Cancer

Flaxseed attenuates the tumor growth stimulating effect of soy protein in ovariectomized athymic mice with MCF-7 human breast cancer xenografts

Authors: Tan, K.P., Chen, J., Ward, W.E., Thompson, L.U.

Publication Name: Int. J. Cancer

Dietary phytoestrogen, serum enterolactone and risk of prostate cancer: the Cancer Prostate Sweden Study (Sweden)

Authors: Hedelin, M., Klint, A., Chang, E.T., Bellocco, R., Johansson, J-E., Andersson, S-O., Heinonen, S-M., et al.

Publication Name: Cancer Causes and Control

Lower Pregnancy Losses in Lactating Dairy Cows Fed a Diet Enriched in α-Linolenic Acid

Authors: Ambrose, D.J., Kastelic, J.P., Corbett, R., Pitney, P.A., Petit, H.V., Small, J.A., Zalkovic, P.

Publication Name: J. Dairy Sci.

Enterolactone as a risk factor for breast cancer: A review of the published evidence

Authors: Boccardo, F., Puntoni, M., Guglielmini, P., Rubagotti, A.

Publication Name: Clinica Chimica Acta

Acute Effects of High-Fat Meals Enriched With Walnuts or Olive Oil on Postprandial Endothelial Function.

Authors: Cort?s, B., N??ez, I., Cof?n, M., Gilabert, R., P?rez-Heras, A., Casals, E., Deulofeu, R., Ros, E.

Publication Name: J. Am. Coll. Cardiol.

Flaxseed and Prostate Cancer:Demon Seed or Seed of Salvation?

Authors: Demark-Wahnefried, W.

Publication Name: Semin. Prev. Altern. Med.

Plasma Enterolignans Are Associated with Lower Colorectal Adenoma Risk

Authors: Kuijsten, A., . Arts, I.C.W., Hollman, P.C.H., van’t Veer, P., Kampman, E

Publication Name: Cancer Epid. Biomarkers Prev.

Flaxseed Oil Supplementation Does Not Affect Plasma Lipoprotein Concentration or Particle Size in Human Subjects

Authors: Harper, C.R., Edwards, M.C., Jacobson, T.A.

Publication Name: J. Nutr.

Inflammation and metabolic disorders.

Authors: Hotamisligil, G.S.

Publication Name: Nature.

Flax Lignans—Analytical Methods and How They Influence Our Understanding of Biological Activity.

Authors: Muir, A.D.

Publication Name: Journal of AOAC Int.

Polyunsaturated fatty acid concentrations in young men and women consuming their habitual diets.

Authors: Bakewell, L., Burdge, G.C., Calder, P.C.

Publication Name: Br. J. Nutr.

Evolutionary aspects of diet, the omega-6/omega-3 ratio and genetic variation: nutritional implications for chronic diseases.

Authors: Simopoulos, A.P.

Publication Name: Biomed. Pharmacother.

Relationship of Plasma Polyunsaturated Fatty Acids to Circulating Inflammatory Markers.

Authors: Ferrucci, L., Cherubini, A., Bandinelli, S., Bartali, B., Corsi, A., Lauretani, F., Martin, A., et.al.

Publication Name: J. Clin. Endocrinol. Metab.

Short-term phytoestrogen supplementation alters insulin-like growth factor profile but not lipid or antioxidant status.

Authors: Woodside, J.V., Campbell, M.J., Denholm, E.E., Newton, L., Honour, J.W., Morton, M.S., Young, I.S., Leathem, A.J.C.

Publication Name: J. Nutr. Biochem.

Plasma enterolactone and genistein and the risk of premenopausal breast cancer.

Authors: Piller, R., J., Chang-Claude, Linseisen, J.

Publication Name: Eur. J. Cancer Prev.

Flaxseed Oil Increases the Plasma Concentrations of Cardioprotective (n-3) Fatty Acids in Humans.

Authors: Harper, C.R., Edwards, M.J., DeFilipis, A.P., Jacobson, T.A.

Publication Name: J. Nutr.

Dietary Flaxseed Supplementation Ameliorates Inflammation and OxidativeTissue Damage in Experimental Models of Acute Lung Injury in Mice.

Authors: Kinniry, P., Amrani, Y., Vachani, A., Solomides, C.C., Arguiri, E., Workman, A., Carter, J., Christofidou-Solomidou, M.

Publication Name: J. Nutr.

A Lignan Complex Isolated from Flaxseed Does Not Affect Plasma Lipid Concentrations or Antioxidant Capacity in Healthy Postmenopausal Women.

Authors: Hallund, J., Ravn-Haren, G., B?gel, S., Tholstrup, T., Tetens, I.

Publication Name: J. Nutr.

Phytoestrogen content of foods consumed in Canada, including isoflavones, lignans, and coumestan.

Authors: Thompson, L.U., Boucher, B.A., Liu, Z., et al.

Publication Name: Nutr. Cancer

Chemopreventive effects of dietary flaxseed on colon tumor development.

Authors: Bommareddy, Arasada, B.L., Mathees, D.P., Dwivedi, C., et al.

Publication Name: Nutr. Cancer

Effects of altering the ratio of dietary n 6 to n 3 fatty acids on insulin sensitivity, lipoprotein size, and postprandial lipemia in men and postmenopausal women aged 45–70 y: the OPTILIP Study.

Authors: Griffin, M.D. Sanders, T.A.B., Davies, I.G., Morgan, L.M., Millward, D.J., Lewis, F., Slaughter, S., et al.

Publication Name: Am. J. Clin. Nutr.

Effects of dietary flaxseed on vascular contractile function and atherosclerosis during prolonged hypercholesterolemia in rabbits.

Authors: Dupasquier, C.M.C. Weber, A.-M., Ander, B.P., Rampersad, P.P., Steigerwald, S., Wigle, J.T., Mitchell, R.W., et al.

Publication Name: Am. J. Physiol. Heart Circ. Physiol.

Plasma Lipoprotein Concentration or Particle Size in Human Subjects.

Authors: Harper, C.H., Edwards, M.C., Jacobson, T.A.

Publication Name: J. Nutr.

The Mediterranean diet: science and practice.

Authors: Willett, W.C.

Publication Name: Public Health Nutr.

The Mediterranean diet for the prevention of cardiovascular diseases.

Authors: De Logeril, M, Salen, P.

Publication Name: Pub. Health Nutr.

Dietary omega-3 fatty acid intake and cardiovascular risk.

Authors: Psota, TL, Gebauer, SK, Kris-Etherton, PM.

Publication Name: Am. J. Cardiol

Long-chain n-3 PUFA: plant v. marine sources.

Authors: Williams, CM, Burdge, G.

Publication Name: Proc. Nutr. Soc.

n-3 fatty acids and cardiovascular disease.

Authors: Breslow, JL

Publication Name: Am. J. Clin. Nutr.

n-3 fatty acid dietary recommendations and food sources to achieve essentiality and cardiovascular benefits.

Authors: Gebauer, SK, Psota, TL, Harris, WS, Kris-Etherton, PM.

Publication Name: Am. J. Clin. Nutr.

Healthy intakes of n-3 and n-6 fatty acids: estimations considering worldwide diversity.

Authors: Hibbeln, JR, Nieminen, LRG, Blasbalg, TL, et al.

Publication Name: Am. J. Clin. Nutr.

Effects of alpha-linolenic acid versus those of EPA/DHA on cardiovascular risk markers in healthy elderly subjects.

Authors: Goyens, PLL, Mensink, RP.

Publication Name: Eur. J. Clin. Nutr.

Dietary Factors That Promote or Retard Inflammation.

Authors: Basu, A., Devaraj, S., Jialal, I.

Publication Name: Arterioscler Thromb. Vasc. Biol.

Differential effects of n-3 polyunsaturated fatty acids on metabolic control and vascular reactivity in the type 2 diabetic ob/ob mouse.

Authors: Mustad, V.A., DeMichele, S., Huanga, Y-S., Mika, A., Lubbers, N., Berthiaume, N., Polakowski, J., Zinker, B.

Publication Name: Metab. Clin. Exp.

Conversion of alpha-linolenic acid in humans is influenced by the absolute amounts of alpha-linolenic acid and linoleic acid in the diet and not by their ratio.

Authors: Goyens, PLL, Spilker, ME, Zock, PL, et al.

Publication Name: Amer. J. Clin. Nutr.

Modulation of the platelet function by diet supplementated with flaxseed and vitamin E in diabetic hamsters.

Authors: Iancu, R.I., Haliga, R., Luca, V., Stitt, P.A., Mocanu, V.

Publication Name: Rev. Med. Chir. Soc. Med. Nat. Iasi.

Analysis of enterolignan glucuronides in serum and urine by HPLC-ESI-MS.

Authors: Knust, U., Hull, W.E., Spiegelhalder, B., Bartsch, H., Strowitzki, T., Owen, R.W.

Publication Name: Food Chem. Toxicol.

Development of an optimized formulation of flaxseed (Linum Usitatissimum).

Authors: Villarroel, M., Pino, L., Hazbun, J.

Publication Name: ALAN

Hanley Flax

Authors: Duguid, S.D., Kenaschuk, E.O., Rashid, K.Y.

Publication Name: Can. J. Plant Sci.

Gene Expression of Stearoyl-ACP Desaturase and Δ12 Fatty Acid Desaturase 2 Is Modulated During Seed Development of Flax (Linum usitatissimum)

Authors: Fofana, B., Cloutier, S., Duguid, S., Ching, J., Rampitsch, C.

Publication Name: Lipids

Genetic mapping of agronomic traits in false flax (Camelina sativa subsp. Sativa)

Authors: Gehringer, A., Friedt, W., Lühs, W., Snowdon, R.J.

Publication Name: Genome

Identification of new gene expression regulators specifically expressed during plant seed maturation

Authors: Gutierrez, L., Conejero, G., Castelain, M., Guénin, S., Verdeil, J-L., Thomasset, B., Van Wuytswinkel, O.

Publication Name: Journal of Experimental Botany

Pinoresinol–lariciresinol reductase gene expression and secoisolariciresinol diglucoside accumulation in developing flax (Linum usitatissimum) seeds

Authors: Hano, C., Martin, I., Fliniaux, O., Legrand, B., Gutierrez, L., Arroo, R.R.J., Mesnard, F., et.al.

Publication Name: Planta

The Onset of Gravisensitivity in the Embryonic Root of Flax1[OA]

Authors: Ma, Z., Hasenstein, K.H

Publication Name: Plant Physiology

Haploid formation in maize, barley, flax, and potato

Authors: Pret’ová, A., Obert, B., Bartošová, Z.

Publication Name: Protoplasma

Distribution, interconversion, and dose response of n 3 fatty acids in humans

Authors: Arterburn, L.M., Hall, E.B., Oken, H.

Publication Name: Am J Clin Nutr

Cyclopeptides of Linum usitatissimum

Authors: Picur, B., Cebrat, M., Zabrock, J., Siemion, I.Z.

Publication Name: J. Pept. Sci.

Dietary a-linolenic acid and health-related outcomes: a metabolic perspective

Authors: Burdge, G.C., Calder, P.C.

Publication Name: Nutrition Research Reviews

Influence of dietary linseed and sunflower oil on sensory characteristics of rainbow trout (Oncorhynchus mykiss)

Authors: Drobná, Z., Zelenka, J., Mrkvicová, E., Kladroba, D.

Publication Name: Czech J. Anim. Sci.

A prospective study of dietary alpha-linolenic acid and the risk of prostate cancer (United States)

Authors: Koralek, D.O., Peters, U., Andriole, G., Reding, D., Kirsh, V., Subar, A., Schatzkin, A., et.al.

Publication Name: Cancer Causes Control

Herb Use Among Health Care Professionals Enrolled in an Online Curriculum on Herbs and Dietary Supplements

Authors: Gardiner, P., Legedza, A., Woods, C., Phillips, R.S., Kemper, K.J.

Publication Name: J Herbal Pharmacotherapy

Supplementation with flax oil and vitamin C improves the outcome of Attention Deficit Hyperactivity Disorder (ADHD)

Authors: Joshi, K., Lad, S., Kale, M., Patwardhan, B., Mahadik, S.P., Patni, B., Chaudhary, A. et. al

Publication Name: Prostaglandins, Leukotrienes and Essential Fatty Acids

Inactivation of Escherichia coli O157:H7 and Salmonella on Mung Beans, Alfalfa, and Other Seed Types Destined for Sprout Production by Using an Oxychloro-Based Sanitizer

Authors: Kumar, M., Kostrzynska, M., Waites, W.M., Warriner, K.

Publication Name: J Food Protection

Phytoestrogens and their metobolites inhibit the sensitivity of the bovine corpus luteum to luteotropic factors.

Authors: Piotrowska, K.K., Woclawek-Potocka, I., Bah, M.M., Piskula, M., Pilawski, W., Bober, A., Skarzynski, D.J.

Publication Name: J Reprod & Dev

Flaxseed in Breadmaking: Effects on Sensory Quality, Aging, and Composition of Bakery Products

Authors: Pohjanheimo, T.A., Hakala, M.A., Tahvonen, R.L., Salminen, S.J. Kallio, H.P.

Publication Name: J Food Sci

Genistein alone and in combination with the mammalian lignans enterolactone and enterodiol induce estrogenic effects on bone and uterus in a postmenopausal breast cancer mouse model

Authors: Power, K.A., Ward, W.E., Chen, J.M., Saarinen, N.M., Thompson, L.U.

Publication Name: Bone

Effect of varying the ratio of n 6 to n 3 fatty acids by increasing the dietary intake of a-linolenic acid, eicosapentaenoic and docosahexaenoic acid, or both on fibrinogen and clotting factors VII and XII in persons aged 45–70 y: the OPTILIP Study

Authors: Sanders, T.A.B., Lewis, F., Slaughter, S., Griffin, B.A., Griffin, M., Davies, I., Millward,D.J., et al.

Publication Name: Am. J. Clin. Nutr.

Effect of Processing and Storage on the Stability of Flaxseed Lignan Added to Bakery Products

Authors: Hyvarinen, H.K Pihlava, J.-M. Hiidenhovi, J.A. Hietaniemi, V. Korhonen, H.J.T. Ryhanen, E.-L.

Publication Name: J. Agric. Food Chem.

Omega-3 fatty acids Their beneﬁ cial role in cardiovascular health

Authors: Schwalfenberg, G.

Publication Name: Can. Fam. Physician

Effect of alpha linolenic acid on cardiovascular risk markers: a systematic review

Authors: Wendland, E. Farmer, A. Glasziou, P. Neil, A.

Publication Name: Heart

Effect of Processing and Storage on the Stability of Flaxseed Lignan Added to Dairy Products

Authors: Hyvarinen, H.K. Pihlava, J.-M. Hiidenhovi, J.A. Hietaniemi, V. Korhonen, H.J.T. Ryhanen, E.-L.

Publication Name: J. Agric. Food Chem.

Assessing Exposure to Lignans and Their Metabolites in Humans

Authors: Lampe, J.W. Atkinson, C. Hullar, M.A.J.

Publication Name: Journal of AOAC International

α-Linolenic Acid-Enriched Diet Prevents Myocardial Damage and Expands Longevity in Cardiomyopathic Hamsters

Authors: Fiaccavento, R. Carotenuto, F. Minieri, M. Masuelli, L. Vecchini, A. Bei, R. Modesti, A. et. al.

Publication Name: Am. J. Pathol.

2005

Long-chain conversion of [13C]linoleic acid and α-linolenic acid in response to marked changes in their dietary intake in men

Authors: Hussein, N., Ah-Sing, E., Wilkinson, P., Leach, C., Griffin, B.A., Millward, D.J.

Publication Name: J. Lipid Res.

Effects of Flax Fiber on Laxation and Glycemic Response in Healthy Volunteers

Authors: Dahl, W.J., Lockert, E.A., Cammer, A.L., Whiting, S.J.

Publication Name: J. Med. Food

Flaxseed supplementation in hyperlipidemic patients

Authors: Mandaşescu, S., Mocanu, V., Dăscaliţa, A.M., Haliga, R., Nestian, I., Stitt, P.A., Luca, V.

Publication Name: Rev. Med. Chir. Soc. Med. Nat. Iasi.

Effect of chronic administration of lignan complex isolated from flaxseed on the hemopoietic system

Authors: Prasad, K.

Publication Name: Mol. Cell. Biochem.

Apolipoprotein E Genotype in Dyslipidemic Patients and Response of Blood Lipids and Inflammatory Markers to Alpha-Linolenic Acid

Authors: Paschos, G.K., Yiannakouris, N., Rallidis, L.S., Davies, I., Griffin, B.A., Panagiotakos, D.B., Skopouli, F.N., et.al.

Publication Name: Angiology

Conversion of α-linolenic acid to longer-chain polyunsaturated fatty acids in human adults

Authors: Burdge, G.C., . Calder, P.C

Publication Name: Reprod. Nutr. Dev.

Plasma and skin concentrations of polyunsaturated fatty acids before and after supplementation with n-3 fatty acids in dogs with atopic dermatitis

Authors: Mueller, R.S., Fettman, M. J., Richardson, K., Hansen, R.A., Miller; A., Magowitz, J., Ogilvie, G.K.,

Publication Name: Am. J. Vet. Res.

Varying the ratio of dietary n 6/n 3 polyunsaturated fatty acid alters the tendency to thrombosis and progress of atherosclerosis in apoE -/- LDLR -/- double knockout mouse

Authors: Yamashita,T., Oda, T.E., Sano, T., Yamashita, T., Ijirua, Y., Giddings, J.C., Yamamoto, J.

Publication Name: Thrombosis Research

The effects of dietary flaxseed on the Fischer 344 rat. III. Protection against CCl4-induced liver injury

Authors: Hemmings, S.J., Song, X.

Publication Name: Cell Biochem. Funct.

Influence of alpha-linolenic acid and fish-oil on markers of cardiovascular risk in subjects with an atherogenic lipoprotein phenotype

Authors: Wilkinson, P., Leach, C., Ah-Sing, E.E., Hussain, N., Miller, G.J., Millward, D.J., Griffin, B.A.

Publication Name: Atherosclerosis

Flaxseed oil and inflammation-associated bone abnormalities in interleukin-10 knockout mice

Authors: Cohen, S.L., Moore, A.M., Ward, W.E.

Publication Name: J. Nutr. Biochem.

Feeding Micronized and Extruded Flaxseed to Dairy Cows: Effects on Blood Parameters and Milk Fatty Acid Composition

Authors: Gonthier, C., Mustafa, A.F., Ouellet, D.R., Chouinard, P.Y., Berthiaume, R., Petit, H.V.

Publication Name: J. Dairy Sci.

Effects of a flaxseed mixture and plant oils rich in a-linolenic acid on the adenoma formation in multiple intestinal neoplasia (Min) mice

Authors: Oikarinen, S.I., Pajari, A-M., Salminen, I., Heinonen, S-M., Adlercreutz, H., Mutanen, M.

Publication Name: Br. J. Nutr.

Whole Sesame Seed Is as Rich a Source of Mammalian Lignan Precursors as Whole Flaxseed

Authors: Coulman, K.D., Liu, Z., Hum, W.Q., Michaelides, J., Thompson, L.U.

Publication Name: Nutr. Cancer

The Usual Intake of Lignans but Not That of Isoflavones May Be Related to Cardiovascular Risk Factors in U.S. Men

Authors: van der Schouw, Y.T., Sampson, L., Willett, W.C., Rimm, E.B.

Publication Name: J. Nutr.

Intakes of Selected Nutrients, Foods, and Phytochemicals and Prostate Cancer Risk in Western New York

Authors: McCann, S.E., Ambrosone, C.B., Moysich, K.B., Brasure, J., Marshall, J.R., Freudenheim, J.L., Wilkinson, G.S., Graham, S.

Publication Name: Nutrition and Cancer

Effect of Flaxseed Consumption on Blood Pressure, Serum Lipids, Hemopoietic System and Liver

Authors: Stuglin, C., Prasad, K.

Publication Name: J. Cardiovasc. Pharmacol. Therapeut.

Lignan contents of Dutch plant foods: a database including lariciresinol, pinoresinol, secoisolariciresinol and matairesinol

Authors: Milder, I.E.J., Arts, I.C.W., van de Putte, B., Venema, D.P., Hollman, P.C.H.

Publication Name: Br. J.Nutr.

Hypocholesterolemic and antiatherosclerotic effect of flax lignan complex isolated from flaxseed

Authors: Prasad, K.

Publication Name: Atherosclerosis

Relation between dietary n-3 and n-6 fatty acids and clinically diagnosed dry eye syndrome in women.

Authors: Miljanović, B., Trivedi, K.A., Dana, M.R., Gilbard, J.P., Buring, J.E., Schaumberg, D.A.

Publication Name: Am. J. Clin. Nutr.

Flaxseed Oil and Bone Development in Growing Male and Female Mice.

Authors: Cohen, S.L., Ward, W.E.

Publication Name: J. Toxicol. Environ. Health

Dietary Lignans: Potential Role in Cancer Prevention

Authors: Webb, A.L., McCullough, M.L.

Publication Name: Nutr. & Cancer

Interplay Between Different Polyunsaturated Fatty Acids and Risk of Coronary Heart Disease in Men.

Authors: Mozaffarian, D., Ascherio, A., Hu, F.B., Stampfer, M.J., Willett, W.C., Siscovick, D.S., Rimm, E.B.

Publication Name: Circulation

Acute effects of monounsaturated fatty acids with and without omega-3 fatty acids on vascular reactivity in individuals with type 2 diabetes.

Authors: West, S.G., Hecker, K.D., Mustad, V.A., Nicholson, S., Schoemer , S.L., Wagner, P., Hinderliter , A.L., et al.

Publication Name: Diabetologia

Dietary Flaxseed Alters Tumor Biological Markers in Postmenopausal Breast Cancer.

Authors: Thompson, L.U., Chen, J.M., Li, T., Strasser-Weippl, K., Goss, P.E.

Publication Name: Clin. Cancer Res.

The Relative Bioavailability of Enterolignans in Humans Is Enhanced by Milling and Crushing of Flaxseed.

Authors: Kuijsten, A., Arts, I.C.W., van’t Veer, P., Hollman, P.C.H.

Publication Name: J. Nutr.

Higher Dietary Intake of Lignans Is Associated with Better Cognitive Performance in Postmenopausal Women.

Authors: Franco, O.H., Burger, H., Lebrun, C.E.I., Peeters, P.H.M., Lamberts, S.W.J., Grobbee, D.E., Van Der Schouw, Y.T.

Publication Name: J. Nutr.

Role of mammalian lignans in the prevention and treatment of prostate cancer.

Authors: McCann, M.J., Gill, C.I.R., McGlynn, H., Rowland, I.R.

Publication Name: Nutr. Cancer

Polyphenols and disease risk in epidemiologic studies.

Authors: Arts, I.C.W. Hollman, P.C.H.

Publication Name: Amer. J. Clin. Nutr.

The Effects of Flaxseed Dietary Supplement on Lipid Profile, Bone Mineral Density, and Symptoms in

Authors: Dodin, S., Lemay, A., Jacques, H., L?gar?, F., Forest, J.-C., M?sse, B.

Publication Name: J. Clin. Endocrinol. Metab.

Intake of the Plant Lignans Secoisolariciresinol, Matairesinol, Lariciresinol, and Pinoresinol in Dutch Men and Women.

Authors: Milder, I.E.J., Feskens, E.J.M., Arts, I.C.W., Bas Bueno de Mesquita, H, Hollman, P.C.H., Kromhout, D.

Publication Name: J. Nutr.

Dietary a-Linolenic Acid Increases Brain but Not Heart and Liver Docosahexaenoic Acid Levels.

Authors: Barcel?-Coblijn, G., Collison, L.W., Jolly, C.A., Murphy, E.A.

Publication Name: Lipids

Effects of Omega-3 Polyunsaturated Fatty Acids on Inflammatory Markers in COPD.

Authors: Matsuyama, W., Mitsuyama, H., Watanabe, M., Oonakahara, K., Higashimoto, I., Osame, M., Arimura, K.

Publication Name: CHEST

Dietary Alpha-linolenic Acid intake & risk of sudden cardiac death & coronary heart disease.

Authors: C M Albert, K Oh, W Whang, J E Manson, C E Chau, M Stampfer, W Willett, F B Hu.

Publication Name: Circulation.

Does Alpha-linolenic Acid intake reduce the risk of coronary heart disease? A review of the evidence.

Authors: D Mozaffarian.

Publication Name: Alternative Therapies in Health & Medicine.

An introduction to dietary/supplemental omega-3 fatty acids for general health and prevention: Part 1.

Authors: Moyad, MA.

Publication Name: Urologic Oncology: Seminars and Original Investigations.

An introduction to dietary/supplemental omega-3 fatty acids for general health and prevention: Part 2.

Authors: Moyad, MA

Publication Name: Urologic Oncology: Seminars and Original Investigations.

The dietary alpha-linolenic acid to linoleic acid ratio does not affect the serum lipoprotein profile in humans

Authors: Goyens, PL, Mensink, RP.

Publication Name: J. Nutr.

The inhibitory effect of flaxseed on the growth and metastasis of estrogen receptor negative human breast cancer xenografts is attributed to both its lignan and oil components

Authors: Wang, L., Chen, J., Thompson, L.U.

Publication Name: Int. J. Cancer

a-Linolenic acid but not conjugated linolenic acid is hypocholesterolaemic in hamsters.

Authors: Yang, L., Leung, K.Y., Cao, Y., Huang, Y., Ratnayake, W.M.N., Chen, Z-U.

Publication Name: Br. J. Nutr.

2126 low linolenic flax.

Authors: Dribnenki, J.C.P., McEachern, S.F., Chen, Y., Green, A.G., Rashid, K.Y.

Publication Name: Can. J. Plant Sci.

Storage Lipid Accumulation and Acyltransferase Action in Developing Flaxseed

Authors: Sørensen, B.M., Furukawa-Stoffer, T.L., Marshall, K.S., Page, E.K., Mir, Z., Forster, R.J., Weselake, R.J.

Publication Name: Lipids

Pleiotropic Effect of Phenolic Compounds Content Increases in Transgenic Flax Plant

Authors: Lorenc-Kukula, K., Amarowicz, R., Oszmianski, J., Doermann, P., Starzycki, M., Skala, J., Zuk, M., et. Al.

Publication Name: J. Agric. Food Chem.

Histological study of embryo-like structures initiated from hypocotyl segments of flax (Linum usitatissimum L.)

Authors: Salaj, J., Petrovská, B., Obert, B., Pret’ová, A.

Publication Name: Plant Cell Rep

Two FAD3 Desaturase Genes Control the Level of Linolenic Acid in Flax Seed

Authors: Vrinten, P., Hu, Z., Munchinsky, M-A., Rowland, G., Qiu, X.

Publication Name: Plant Physiology

Flax Species Polymorphism for Isozyme and Metabolic Markers

Authors: Yurenkova, S.I., Kubrak, S.V., Titok, V.V., Khotyljova, L.V.

Publication Name: Russian J. of Genetics,

Alpha-linolenic acid and heart rate variability in women examined for coronary artery disease

Authors: Christensen, J.H., Schmidt, E.B., Mølenberg, D., Toft, E

Publication Name: Nutr, Metab & Cardiovascular Dis

Dietary Linolenic Acid and Adjusted QT and JT Intervals in the National Heart, Lung, and Blood Institute Family Heart Study

Authors: Djoussé, L., Rautaharju, P.M., Hopkins, P.N., Whitsel, E.A., Arnett, D.K., Eckfeldt, J.H., Province, M.A. Ellison, C.

Publication Name: J Am Coll Cardiol

Dietary Linolenic Acid Is Inversely Associated With Calcified Atherosclerotic Plaque in the Coronary Arteries The National Heart, Lung, and Blood Institute Family Heart Study

Authors: Djoussé, L., Arnett, D.K., Carr, J.J., Eckfeldt, J.H., Hopkins, P.N., Province M.A., Ellison, R.C.

Publication Name: Circulation.

Stability of a-Linolenic Acid and Secoisolariciresinol Diglucoside in Flaxseed-Fortified Macaroni

Authors: Hall, C.A., Manthey, F.A., Lee, R.E., Niehaus, M.

Publication Name: J Food Sci

Effect of dietary fish oil substitution with linseed oil on the performance, tissue fatty acid profile, metabolism, and oxidative stability of Atlantic salmon

Authors: Menoyo, D., López-Bote, C.J., Obach A., Bautista, J.M.

Publication Name: J. Anim. Sci.

Long-chain n–3 polyunsaturated fatty acids in plasma in British meat-eating, vegetarian, and vegan men

Authors: Rosell, M.S., Lloyd-Wright, Z., Appleby, P.N., Sanders, T.A.B., Allen, N.E., Key, T.J.

Publication Name: Am. J. Clin. Nutr.

PHYSICOCHEMICAL PROPERTIES OF FRESHLY BAKED AND STORED WHOLE-WHEAT MUFFINS WITH AND WITHOUT FLAXSEED MEAL

Authors: Shearer, A.E.H., Davies, C.G.A.

Publication Name: J. Food Quality

Structural investigations of the neutral polysaccharide of Linum usitatissimum L. seeds mucilage

Authors: Warrand, J., Michaud, P., Picton, L., Muller, G., Courtois, B., Ralainirina, R., Courtois, J.

Publication Name: Int. J. Biological Macromolecules

Chemopreventive Effects of Dietary Flaxseed Oil on Colon Tumor Development.

Authors: Dwivedi, C. Natarajan, K. Matthees, D.P.

Publication Name: Nutr. & Cancer

Compartmental modeling to quantify a-linolenic acid conversion after longer term intake of multiple tracer boluses

Authors: Goyens, P.L.L. . Spilker, M.E Zock, P.L. Katan, M.B. Mensink, R.P.

Publication Name: Journal of Lipid Research

Physico-Chemical Stability of Flaxseed Oil with Natural

Authors: Jaswir, I. Kitts, D.D. Che Man, Y.B Hassan, T.H.

Publication Name: Journal of Oleo Science

Dose effect of alpha-linolenic acid on lipid metabolism in the hamster.

Authors: Morise, A. Mourot, J. Riottot, M. Weill, P. Fenart, E. Hermier, D.

Publication Name: Reprod. Nutr. Dev.

Impact of Feeding Bread Enriched with Flaxseed on Plasma Profile of Hyperlipidemic Rats – A Short Report.

Authors: Mohamed, D.A. El-Hariri, D.M. Al-Okbi, S.Y.

Publication Name: Pol.J.Food Nutr.

2004

The effects of dietary flaxseed on the Fischer 344 rat: II. Liver y -glutamyltranspeptidase activity

Authors: Hemmings, S.J., Westcott, N., Muir, A., Czechowicz, D.

Publication Name: Cell. Biochem. Funct.

The effects of dietary flaxseed on the Fischer 344 rat: I. Development, behaviour, toxicity and the activity of liver y-glutamyltranspeptidase

Authors: Hemmings, S.J., Barker, L.,

Publication Name: Cell. Biochem. Funct.

Effect of Feeding Whole, Unprocessed Sunflower Seeds and Flaxseed on Milk Production, Milk Composition, and Prostaglandin Secretion in Dairy Cows

Authors: Petit, H.V., Germiquet, C., Lebel, D.

Publication Name: J. Dairy Sci.

Effects of Feeding Micronized and Extruded Flaxseed on Ruminal Fermentation and Nutrient Utilization by Dairy Cows

Authors: Gonthier, C., Mustafa, A.F., Berthiaume, R., Petit, H.V., Martineau, R., Ouellet, D.R.

Publication Name: J. Dairy Sci.

Effects of a medium chain triglyceride oil mixture and alpha-lipoic acid diet on body composition, antioxidant status, and plasma lipid levels in the Golden Syrian hamster

Authors: Wollin, S.D., Wang, Y., Kubow, S., Jones, P.J.H.

Publication Name: J. Nutr. Biochem.

Modulation of Renal Injury in pcy Mice by Dietary Fat Containing n-3 Fatty Acids Depends on the Level and Type of Fat

Authors: Sankaran, D., Lu, J., Bankovic-Calic, N., Ogborn, M.R., Aukema, H.M.

Publication Name: Lipids

Dietary secoisolariciresinol diglucoside and its oligomers with 3-hydroxy-3-methyl glutaric acid decrease vitamin E levels in rats

Authors: Frank, J., Eliasson, C., Leroy-Nivard, D., Budek, A., Lundh, T., Vessby, B., ?man, P., Kamal-Eldin, A.

Publication Name: Br. J. Nutr.

Piilot Study to Explore Effects of Low-Fat, Flaxseed-Supplemented Diet on Proliferation of Benign Prostatic Epithelium and Prostate-Specific Antigen

Authors: Demark-Wahnefried, W., Robertson, C.N., Walther P.J., Polascik, T.J., Paulson, D.F., Vollmer, R.T.

Publication Name: Urology

Phytoestrogen Tissue Levels in Benign Prostatic Hyperplasia and Prostate Cancer and their Association with Prostatic Diseases

Authors: Br?ssner, C., Petritsch, K., Fink K., Auprich M., Madersbacher, S., Adlercreutz, H., Rehak P., Petritsch, P.

Publication Name: Urology

Prospective study of plasma enterolactone and prostate cancer risk (Sweden)

Authors: Stattin, P., Bylund, A., Biessy, A., Kaaks, R., Hallmans, G., Adlercreutz, H.

Publication Name: Cancer Causes and Control

Phytoestrogens and Their Human Metabolites Show Distinct Agonistic and Antagonistic Properties on Estrogen Receptor a (ERa) and ERb in Human Cells

Authors: Mueller, S.O., Simon, S., Chae, K., Metzler, M., Korach, K.S.

Publication Name: Toxicol. Sci.

Dietary Flaxseed Protects against Ventricular Fibrillation Induced by Ischemia-Reperfusion in Normal and Hypercholesterolemic Rabbits

Authors: Ander, B.P., Weber, A.R., Rampersad, P.P., Gilchrist, J.S.C., Pierce, G.N., Lukas, A.

Publication Name: J. Nutr.

Flaxseed and Cardiovascular Risk.

Authors: Bloedon, L.T., Szapary, P.O.

Publication Name: Nutrition Reviews.

Dietary Fiber and C-Reactive Protein: Findings from National Health and Nutrition Examination Survey Data.

Authors: Ajani, U.A., Ford, E.S., Mokdad, A.H.

Publication Name: J. Nutr.

Dietary Flaxseed Enhances the Inhibitory Effect of Tamoxifen on the Growth of Estrogen-Dependent Human Breast Cancer (MCF-7) in Nude Mice.

Authors: Chen, J., Hui, E., Ip, T., Thompson, L.U.

Publication Name: Clin. Cancer Res.

Increased alpha-linolenic acid intake lowers C-reactive protein, but has no effect on markers of atherosclerosis.

Authors: Bemelmans, W.J.E., Lefrandt,J.D., Feskens, E.M.J., van Haelst, P.L., Broer, J., Meyboom-de Jong, B., May, J.F., et al.

Publication Name: Eur. J. Clin. Nutr.

Dietary alpha-linolenic acid reduces inflammatory and lipid cardiovascular risk factors in hypercholesterolemic men and women.

Authors: Zhao, G., Etherton, T.D., Martin, K.R., et al.

Publication Name: J. Nutr.

Consumption of (n-3) Fatty Acids Is Related to Plasma Biomarkers of Inflammation and Endothelial Activation in Women.

Authors: Lopez-Garcia, E., Schulze, M.B., Manson, J.E., Meigs, J.B., Albert, C.M., Rifai, N., Willett, W.C., Hu, F.B.

Publication Name: J. Nutr.

Adherence to the Mediterranean Diet Attenuates Inflammation and Coagulation Process in Healthy Adults. The ATTICA Study.

Authors: Chrysohoou, C., Panagiotakos, D.B., Pitsavos, C., Das, U.N., Stefanadis, C.

Publication Name: J. Am. Coll. Cardiol.

Dietary intake of n 3 and n 6 fatty acids and the risk of prostate cancer.

Authors: Leitzmann, M.F., Stampfer, M.J., Michaud, D.S., Augustsson, K., Colditz, G.C., Willett, W.C., Giovannucci, E.L.

Publication Name: Am. J. Clin. Nutr.

Diet and risk of ischemic heart disease in India.

Authors: Rastogi, T., Reddy, K.S., Vaz, M., Spiegelman, D., Prabhakaran, D., Willett, W.C., Stampfer, M.J., Ascherio, A.

Publication Name: Am. J. Clin. Nutr.

Alpha-linolenic acid and the risk of prostate cancer. What is the evidence?

Authors: N Attar-Bashi, A G Frauman, A J Sinclair.

Publication Name: The Journal of Urology/

Alpha-linolenic acid and the risk of prostate cancer.

Authors: Letter to the editor

Publication Name: Lipids.

Dietary Alpha-linolenic Acid is associated with reduced risk of fatal coronary heart disease, but increased prostate cancer risk: A meta-analysis.

Authors: I Brouwer, M B Katan, P L Zock.

Publication Name: Am Society for Nutritional Sciences.

Use and misuse of dietary fatty acids for the prevention and treatment of coronary heart disease.

Authors: M de Lorgeril, P Salen.

Publication Name: Reprod. Nutr. Dev.

Fish intake, marine omega-3 fatty acids, & mortality in a cohort of postmenopausal women.

Authors: A R Folsom, Z Demissie.

Publication Name: Am J Epidemiol.

Supplementation with flaxseed alters estrogen metabolism in postmenopausal women to a greater extent than does supplementation with an equal amount of soy

Authors: Brooks, J.D., Ward, W.E., Lewis, J.E., Hilditch, J., Nickell, L., Wong, E., Thompson, L.U.

Publication Name: Am. J. Clin. Nutr.

Effects of Omega-3 Fatty Acids on Cardiovascular Disease.

Authors: Tufts-New England Medical Cent

Publication Name: AHRQ Publication.

Dietary n-6 and n-3 fatty acid balance and cardiovascular health.

Authors: V Wijendran, K C Hayes.

Publication Name: Annu. Rev. Nutr.

C-Reactive Protein Increases Oxygen Radical Generation by Neutrophils

Authors: Prasad, K.

Publication Name: J. Cardiovasc. Pharmacol. Ther.

Nutrition and cancer: A review of the evidence for an anti-cancer diet

Authors: Donaldson. M.S.

Publication Name: Nutr.J.

Alpha-linolenic acid supplementation during human pregnancy does not effect cognitive functioning.

Authors: R H M De Groot, J Adam, J Jolles, G Hornstra.

Publication Name: Prost. Leuk. Essen. Fatty Acids.

Effect of alpha-linolenic acid supplementation during pregnancy on maternal and neonatal polyunsaturated fatty acid status and pregnancy outcome.

Authors: R H M De Groot, G Hornstra, A C Houwelingen, F Roumen.

Publication Name: Am. J. Clin. Nutr.

Dietary fibre: more than a matter of dietetics. II. Preventative and therapeutic uses.

Authors: Trepel, F.

Publication Name: Wien. Klin. Wochenschr.

Flaxseed reduces plasma cholesterol and atherosclerotic lesion formation in ovariectomized Golden Syrian hamsters.

Authors: Lucas, E.A., Lightfoot, S.A., Hammond, L.J., Devareddy, L., Khalil, D.A., Daggy, B.P., Smith, B.J., et.al.

Publication Name: Atherosclerosis

2090 low linolenic acid flax.

Authors: Dribnenki, J.C.P., McEachern, S.F., Chen, Y., Green, A.G., Rashid, K.Y.

Publication Name: Can. J. Plant Sci.

Registration of ‘Nekoma’ Flax

Authors: Hammond, J.J., Miller, J.F., Rasmussen, J.B.

Publication Name: Crop Science

Prairie Blue flax

Authors: Duguid, S.D., Kenaschuk, E.O., Rashid, K.Y.

Publication Name: Can. J. Plant Sci.

Registration of ‘York’ Flax

Authors: Hammond, J.J., Miller, J.F., Statler, G.D.

Publication Name: Crop Science

Effect of medium osmotic potential on callus induction and shoot regeneration in flax anther culture

Authors: Chen, Y., Dribnenki, P.,

Publication Name: Plant Cell Rep

Lignan accumulation in cell cultures of Linum strictum ssp. strictum L.

Authors: Vasilev, N., Ionkova, I.

Publication Name: Acta Pharm.

ISSR-Based Clustering of Cultivated Flax Germplasm is Statistically Correlated to Thousand Seed Mass

Authors: Wiesnerová, D., Wiesner, I.

Publication Name: Molecular Biotechnology

Polyhydroxybutyrate synthesis in transgenic flax

Authors: Wróbel, M., Zebrowski, J., Szopa, J.

Publication Name: Journal of Biotechnology

n–3 Fatty acids and cardiovascular disease: evidence explained and mechanisms explored

Authors: Calder, P.C.

Publication Name: Clinical Science

Effects of Extracts of Commonly Consumed Food Supplements and Food Fractions on the Permeability of Drugs Across Caco-2 Cell Monolayers

Authors: Laitinen, A.L., Tammela, P.S., Galkin, A., Vuorela, H.J., Marvola, M.L., Vuorela, P.M.

Publication Name: J Pharmaceutical Res

Background diet influences the anti-inflammatory effect of a-linolenic acid in dyslipidaemic subjects

Authors: Paschos, G.K., Rallidis, L.S., Liakos, G.K., Panagiotakos, D., Anastasiadis, G., Votteas, V., Zampelas, A.

Publication Name: Br J Nutr

CDC/AHA Workshop on Markers of Inflammation and Cardiovascular Disease: Application to Clinical and Public Health Practice: Report From the Clinical Practice Discussion Group

Authors: Smith, Jr, S.C., Anderson, J.L., Cannon, R.O., Fadl, Y.Y., Koenig, W., Libby, P., Lipshultz, S.E., et al

Publication Name: Circulation

Mammary Gland Morphogenesis Is Enhanced by Exposure to Flaxseed or Its Major Lignan During Suckling in Rats

Authors: Tan, K.P., Chen, J., Ward, W.E., Thompson, L.U.

Publication Name: Exp. Biol. Med.

Effects of flaxseed on breast cancer growth.

Authors: de Lemos, M. O'Brien, R.K.

Publication Name: J. Oncol. Pharm. Prac.

Dietary alpha-Linolenic Acid Is Associated with Reduced Risk of Fatal Coronary Heart Disease, but Increased Prostate Cancer Risk: A Meta-Analysis

Authors: Brouwer, I.A. Katan, M.B. Zock, P.L.

Publication Name: J. Nutr.

Effect of α-Linolenic Acid�Containing Linseed Oil on Coagulation in Type 2 Diabetes

Authors: Tohgi, N.

Publication Name: Diabetes Care

2003

Effects of flaxseed supplementation on milk production, milk fatty acid composition and nutrient utilization by lactating dairy cows.

Authors: Soita, H.W., Meier, J.A., Fehr, M., Yu, P., Christensen, D.A., McKinon, J.J., Mustafa, A.F.

Publication Name: Arch Tierernahr.

Does conjugated linoleic acid increase conversion of α-linolenic acid to docosahexaenoic acid in humans?

Authors: Attar-Bashi, N.M., Li, D., Sinclair, A.J.

Publication Name: Asia Pac. J. Clin. Nutr.

Effect of hens fed dietary flaxseed with and without a fatty liver supplement on hepatic, plasma and production characteristics relevant to fatty liver haemorrhagic syndrome in laying hens

Authors: Schumann, B.E., Squires, E.J., Sinclair, A.J. Hunter, B.

Publication Name: Br. Poultry Sci.

Flaxseed increased a-linolenic and eicosapentaenoic acid and decreased arachidonic acid in serum and tissues of rat dams and offspring

Authors: Wiesenfeld, P.W., Babu, U.S., Collins, T.F.X., Sprando, R., O’Donnell, M.W., Flynn, T.J., Black, T., Olejnik, N.

Publication Name: Food Chem. Tox.

Effect of Flaxseed and Wheat Bran on Serum Hormones and Lignan Excretion in Premenopausal Women

Authors: Frische, E.J., Hutchins, A.M., Martini, M.C., Thomas, W., Slavin, J.L.

Publication Name: J. Am. Coll. Nutr.

Effects of Flaxseed Oil on Serum Lipids and Atherosclerosis in Hypercholesterolemic Rabbits

Authors: Lee, P., Prasad, K.

Publication Name: J. Cardiovasc. Pharmacol. Therapeut.

Digestion, Milk Production, Milk Composition, and Blood Composition of Dairy Cows Fed Formaldehyde Treated Flaxseed or Sunflower Seed

Authors: Petit, H.V.

Publication Name: J. Dairy Sci.

Comparison of the effects of linseed oil and different doses of fish oil on mononuclear cell function in healthy human subjects

Authors: Wallace, F.A., Miles, E.A., Calder, P.C.

Publication Name: Br. J. Nutr.

Lignans and tamoxifen, alone or in combination, reduce human breast cancer cell adhesion, invasion and migration in vitro

Authors: Chen, J., Thompson, L.U.

Publication Name: Breast Cancer Res.Treatment Volume 80; Pages 163–170.

Serum Enterolactone Concentration Is Not Associated with Prostate Cancer Risk in a Nested Case-Control Study

Authors: Kilkkinen, A., Virtamo, J., Virtanen, M.J., Adlercreutz, H., Albanes, D., Pietinen, P.

Publication Name: Cancer Epid. Biomarkers & Prevention

The Effect of Flax Seed Cultivars with Differing Content of -Linolenic Acid and Lignans on Responses to Mental Stress

Authors: Spence, J.D., Thornton, T., Muir, A.D., Westcott, N.D.

Publication Name: J. Am. Coll. Nutr.

Phytoestrogen Intake and Endometrial Cancer Risk

Authors: Horn-Ross, P.L., John, E.M., Canchola, A.J., Stewart, S.L., Lee, M.M.

Publication Name: J. Natl.Cancer Inst.

Phytoestrogens in Botanical Dietary Supplements: Implications for Cancer

Authors: Piersen, C.E.

Publication Name: Integr. Cancer Ther.

Centers for Disease Control and Prevention and the American Heart Association and Public Health Practice: A Statement for Healthcare Professionals From the Markers of Inflammation and Cardiovascular Disease: Application to Clinical.

Authors: Pearson, T.A., Mensah, R.W., G.A., Alexander, Anderson, J.L., Cannon, R.O., Criqui, M., Fadl, Y.Y., et. al.

Publication Name: Circulation

Risk of Human Ovarian Cancer Is Related to Dietary Intake of Selected Nutrients, Phytochemicals and Food Groups.

Authors: McCann, S.E., Freudenheim, J.L., Marshall, J.R., Graham, S.

Publication Name: J. Nutr.

Intake of Lignans Is Associated with Serum Enterolactone Concentration in Finnish Men and Women.

Authors: Kilkkinen, A., Valstra, L., Virtamo, J., Stumpf, K., Adlercreutz, H., Pietinen, P.

Publication Name: J. Nutr.

Diet, Nutrition, and Cancer Prevention: The Postgenomic Era.

Authors: Go, V.L.W., Butrum, R.R., Wong, D.A.

Publication Name: J. Nutr.

Achieving optimal essential fatty acid status in vegetarians: currentknowledge and practical implications.

Authors: Davis, B.C., Kris-Etherton. P.M.

Publication Name: Am. J. Clin. Nutr.

Risk of Cardiovascular Disease-related and all-cause death according to Serum Concentrations of Enterolactone.

Authors: Vanharanta, M., Voutilainen, S., Rissanen, T.H., Adlercreutz, H., Salonen, J.T.

Publication Name: Arch. Intern. Med.

Plant- and marine-derived n-3 polyunsaturated fatty acids have differential effects on fasting and postprandial blood lipid concentrations and on the susceptibility of LDL to oxidative modification in moderately hyperlipidemic subjects.

Authors: Finnegan, Y.E., Minihane, A.M., Leigh-Firbank, E.C., Kew, S., Meijer, G.W., Muggli, R., Calder, P.C., Williams, C.M.

Publication Name: Am. J. Clin. Nutr.

Dietary linolenic acid and carotid atherosclerosis: the National Heart, Lung, and Blood Institute Family Heart Study.

Authors: Djouss?, L., Folsom, A.R., Province, M.A., Hunt, S.C., Ellison, R.C.

Publication Name: Am. J. Clin. Nutr.

Dietary Flaxseed Meal is More Protective Than Soy Protein Concentrate Against Hypertriglyceridemia and Steatosis of the Liver in an Animal Model of Obesity.

Authors: Bhathena, S.J., Ali, A.A., Haudenschild, C., Latham, P., Ranich, T., Mohamed, A.I., Hansen, C.T., Velasquez, M.T.

Publication Name: J. Am. Coll. Nutr.

Suppression of Oxidative Stress as a Mechanism of Reduction of Hypercholesterolemic Atherosclerosis by Aspirin

Authors: Prasad, K., Lee, P.

Publication Name: J. Cardiovasc. Pharmacol. Ther.

Impact of high flaxseed diet on mitogen-induced proliferation, IL-2 production, cell subsets and fatty acid composition of spleen cells

Authors: Babu, U.S., Wiesenfeld, P.W., Collins, T.F.X., Sprando, R., Flynn, T.J., Black,T., Olejnik, N., Raybourne, R.B.

Publication Name: Food Chem. Toxicol.

Milk Conjugated Linoleic Acid Response to Fish Oil Supplementation of Diets Differing in Fatty Acid Profiles

Authors: AbuGhazaleh, A.A., Schingoethe, D.J., Hippen, A.R., Kalscheur, K.F.

Publication Name: J. Dairy Sci.

Adipose tissue alpha-linolenic acid and nonfatal acute myocardial infarction in Costa Rica.

Authors: A Baylin, E K Kabagambe, A Ascherio, D Spiegelman, H Campos.

Publication Name: Circulation.

n-3 polyunsaturated fatty acids, fatal ischemic heart disease, and nonfatal myocardial infarction in older adults: the cardiovaascular health study.

Authors: R Lemaitre, I King, D Mozaffarian, L Kuller, R Tracy, D Siscovick.

Publication Name: Am J Clin Nutr.

Effects of Dietary fatty acids & carbohydrates on the ratio of Serum total to HDL cholesterol & on serum lipids & apolipoproteins: a meta-analysis of 60 controlled trials.

Authors: R Mensink, P Zock, A Kester, M Katan.

Publication Name: Am J Clin Nutr.

A Practical approach to increasing intakes of n-3 polyunsaturated fatty acids: use of novel foods enriched with n-3 fats.

Authors: R Metcalf, M James, E Mantzioris, I Cleland.

Publication Name: European Journal of Clinical Nutrition.

The Serum LDL/HDL Cholesterol Ratio is Influenced More Favorably by Exchanging Sarurated with Unsaturated Fat Than by Reducing Saturated Fat in the diet of women.

Authors: H M?ller, A Lindman, A Brants?ter, J Perdersen.

Publication Name: J Nutr.

n-3 fatty acids and 5 year risk of death and cardiovascular disease events in patients with coronary artery disease.

Authors: A T Erkkila, S Lehto, K Pyorala, M I J Uusitupa.

Publication Name: Am. J. Clin. Nutr.

Effects of flaxseed and defatted flaxseed meal on reproduction and development in rats

Authors: Collins, T.F.X., Sprando, S.L., Black, T. N., Olejnik, N., Wiesenfeld, P.W., Babu, U.S., Bryant, M., et. al.

Publication Name: Food Chem. Toxicol.

Dietary alpha-linolenic acid increases the n-3 PUFA content of sow’s milk and the tissues of the suckling piglet.

Authors: R P Bazinet, E G McMillan, S C Cunnane.

Publication Name: Lipids.

Plausible mechanisms for effects of long-chain polyunsaturated fatty acids on growth.

Authors: A Lapillonne, S D Clarke, W C Herd.

Publication Name: J. Pediatr.

Fatty acid profiles, antioxidant status, and growth of preterm infants fed diets without or with long-chain.

Authors: B Koletzko, U Sauerwald, U Keicher, H. Saule, S. Wawatschek, H Bohles, K Bervoets, M Fleith,

Publication Name: Eur. J. Nutr.

Preterm infant formula supplementation with alpha-linolenic acid and docosahexaenoic acid.

Authors: A Rodriguez, D Raederstorff, P Sarda, C Lauret, F Mendy, B Descomps.

Publication Name: Eur. J. Clin. Nutr.

Supplementation of female rats with alpha-linolenic acid leads to the same omega-6/omega-3 LC-PUFA accretion in mother tissues and in fetal and newborn brains.

Authors: A Valenzuela, R von Bernhardi, V Valenzuela, G Ramfrez, S J Alarcon.

Publication Name: Ann. Nutr. Metab.

Immune Response of Postpartum Dairy Cows Fed Flaxseed

Authors: Lessard, M., Gagnon, N., Petit, H.V.

Publication Name: J. Dairy Sci.

Exposure to Flaxseed or Its Purified Lignan during Suckling Inhibits Chemically Induced Rat Mammary Tumorigenesis.

Authors: Chen, J., Tan, K.P., Ward, W.E., Thompson, L.U.,

Publication Name: Exp. Biol. Med.

Dietary Mono- and polyunsaturated fatty acids similarly increase plasma apoliprotein A-IV concentrations in healthy men and women.

Authors: M Kratz, U Wahrburg, A Eckardstein, B Ezeh, G Assmann, F Kronenberg.

Publication Name: J Nutr

Developmental effects of serum from flaxseed-fed rats on cultured rat embryos

Authors: Flynn, T.J., Collins, T.F.X., Sprando, R.L., Black, T.N., Ruggles, D.I., Wiesenfeld, P.W., Babu, U.S.

Publication Name: Food Chem. Toxicol.

CDC Mons flax.

Authors: Rowland, G.G., Hormis, Y.A., Rashid, K.Y.

Publication Name: Can. J. Plant Sci.

Identification and Stereochemical Characterization of Lignans in Flaxseed and Pumpkin Seeds.

Authors: Sicilia, T., Niemeyer, H.B., Honig, D.M., Metzler, M.

Publication Name: J. Agric. Food Chem.

Lignan Precursors From Flaxseed or Rye Bran Do Not Protect Against the Development of Intestinal Neoplasia in ApcMin Mice.

Authors: van Kranen, H.J., Mortensen, A., Sørensen, I.K., van den Berg-Wijnands, J., Beems, R., Nurmi, T., Adlercreutz, H., van Kreijl, C.F.

Publication Name: Nutr. & Cancer

Lightning flax

Authors: Duguid, S.D., Kenaschuk, E.O., Rashid, K.Y.

Publication Name: Can. J. Plant Sci.

Linola™ 2047 low linolenic flax

Authors: Dribnenki, J.C.P., McEachern, S.F., Chen, Y., Green, A.G., Rashid, K.Y.

Publication Name: Can. J. Plant Sci.

Macbeth flax

Authors: Duguid, S.D., Kenaschuk, E.O., Rashid, K.Y.

Publication Name: Can. J. Plant Sci.

OXYGEN REQUIREMENT OF GERMINATING FLAX SEEDS

Authors: Kuznetsov, O.A., Hasenstein, K.H.

Publication Name: Adv. Space Res.

GERMINATION AND ELONGATION OF FLAX IN MICROGRAVITY

Authors: Levine, H.G., Anderson, K., Boody, A., Cox, D., Kuznetsoti, O.A., Hasenstein, K.H.

Publication Name: Adv. Space Res.

Supplementing lactating women with flaxseed oil does not increase docosahexaenoic acid in their milk

Authors: Francois, C.A., Connor, S.L., Bolewicz, L.C., Connor, W.E.

Publication Name: Am J Clin Nutr Volume 77; Pages 226-33

Linolenic acid prevents neuronal cell death and paraplegia after transient spinal cord ischemia in rats

Authors: Lang-Lazdunski, L., Blondeau, N., Jarretou, G., Lazdunski, M., Heurteaux, C.

Publication Name: J Vasc Surg

Phytoestrogen-Rich Diets Modulate Expression of Brca1 and Brca2 Tumor Suppressor Genes in Mammary Glands of Female Wistar Rats

Authors: Vissac-Sabatier, C., Coxam, V., Déchelotte, P. Picherit, C., Horcajada, M-N., Davicco, M-J., Lebecque, P., et al

Publication Name: Cancer Research

Dietary flaxseed meal reduces proteinuria and ameliorates nephropathy in an animal model of type II diabetes mellitus

Authors: Velasquez, M.T. Bhathena, S.J. Ranich, T. Schwatrz, A.M. Kardon, D.E. Ali, A.A. Haudenschild, C.C. Hansen, C.T.

Publication Name: Kidney International

Dietary linolenic acid is inversely associated with plasma triacylglycerol: the National Heart, Lung, and Blood Institute Family Heart Study

Authors: Djouss�, L. Hunt, S.C. Arnett, D.K. Province, M.A. Eckfeldt, J.H. Ellison, R.C.

Publication Name: Am. J. Clin. Nutr.

2002

Bioactive Compounds in Foods: Their Role in the Prevention of Cardiovascular Disease and Cancer

Authors: Kris-Etherton, P.M., Hecker, K.D., Bonanome, A., Coval, S.M., Binkoski, A.E., Hilpert, K.F., Griel, A.E., Etherton, T.D.

Publication Name: Am. J. Med.

Differential effects of dietary flaxseed protein and soy protein on plasma triglyceride and uric acid levels in animal models

Authors: Bhathena, S.J., Ali, A.A., Mohamed, A.I., Hansen, C.T., Velasquez, M.T.

Publication Name: J. Nutr. Biochem.

Dietary Flax Oil Reduces Renal Injury, Oxidized LDL Content, and Tissue n-6/n-3 FA Ratio in Experimental Polycystic Kidney Disease

Authors: Ogborn, M.R., Nitschmann, E., Bankovic-Calic, N., Weiler, H.A., Aukema, H.

Publication Name: Lipids

Dietary Flaxseed Inhibits Human Breast Cancer Growth and Metastasis and Downregulates Expression of Insulin-Like Growth Factor and Epidermal Growth Factor Receptor

Authors: Chen, J., Stavro, P.M., Thompson, L.U.

Publication Name: Nutr. Cancer

Circulating Enterolactone and Prostate Cancer Risk: A Nordic Nested Case-Control Study

Authors: Stattin, P., Adlercreutz, H., Tenkanen, L., Jellum, E., Lumme, S., Hallmans, G., Harvei, S., et al.

Publication Name: Int. J. Cancer

Review: Mammalian phytoestrogens: enterodiol and enterolactone

Authors: Wang, L-Q.

Publication Name: J. Chromatography B,

Comparative Study of Concentration of Isoflavones and Lignans in Plasma and Prostatic Tissues of Normal Control and Benign Prostatic Hyperplasia

Authors: Hong, S.J., Kim, S.I., Kwon, S.M., Lee, J.R., Chung, B.C.

Publication Name: Yonsei Med. J.

Effect of Flaxseed Supplementation on Prostatic

Authors: Lin, X., Gingrich, J.R., Bao, W., Li, J., Haroon, J.A., Demark-Wahnefried, W.

Publication Name: Urology

Phytoestrogens and Thyroid Cancer Risk: The San Francisco Bay Area Thyroid Cancer Study.

Authors: Horn-Ross, K.J., P.L., Hoggatt, Lee, M.M.

Publication Name: Cancer Epid. Biomarkers Prev.

Flaxseed inhibits metastasis and decreases extracellular vascular endothelial growth factor in human breast cancer xenografts.

Authors: Dabrosin, C., Chen, J., Wang, L., Thompson, L.U.

Publication Name: Cancer Lett.

What Is the Role of α-Linolenic Acid for Mammals?

Authors: Sinclair, A.J., Attar-Bashi, N.M., Li, D.

Publication Name: Lipids

Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease.

Authors: Kris-Etherton, P.M., Harris, W.S., Appel, L.J.

Publication Name: Circulation

Dietary Intake of Phytoestrogens Is Associated with a Favorable Metabolic Cardiovascular Risk Profile in Postmenopausal U.S. Women: The Framingham Study.

Authors: de Kleijn, M.J.J., van der Schouw, V.T., Wilson, P.W.F., Grobbee, D.E., Jacques, P.F.

Publication Name: J. Nutr.

A Systematic Screening of Total Antioxidants in Dietary Plants.

Authors: Halvorsen, B.L., Holte, K., Myhrstad, M.C.W., Barikmo, I., Hvattum, E., Remberg, S.F., Wold, A-B., et. al.

Publication Name: J. Nutr.

Beneficial role of dietary phytoestrogens in obesity and diabetes.

Authors: Bhathena, S.J., Velasquez, M.T.

Publication Name: Am. J. Clin. Nutr.

Effect of an Indo-Mediterranean diet on progression of coronary artery disease in high risk patients (Indo-Mediterranean Diet Heart Study): a randomised single-blind trial.

Authors: Singh, R.B., Dubnov, G., Niaz, M.A., Ghosh, S., Singh, R., Rastogi, S.S., Manor, O., et al.

Publication Name: Lancet

The beneficial effect of alpha-linolenic acid in coronary artery disease is not questionable. Letters to the Editor.

Authors: Renaud, S.

Publication Name: Am. J. Clin. Nutr.

An incident case-referent study on plasma enterolactone and breast cancer risk.

Authors: Hult?n, K., Winkvist, A., Lenner, P., Johansson, R., Adlercreutz, H., Hallmans, A.

Publication Name: Eur. J. Nutr.

Flaxseed Dietary Supplement Versus Hormone Replacement Therapy in Hypercholesterolemic

Authors: Lemay, A., Dodin, S., Kadri, N., Jacques, H., Forest, J.-C.

Publication Name: Obstet. Gynecol.

Flaxseed Improves Lipid Profile without Altering Biomarkers of Bone Metabolism in Postmenopausal Women.

Authors: Lucas, E.A., Wild, R.D., Hammond, L.J., Khalil, D.A., Juma, S., Daggy, B.P., Stoecker, B.J., Arjmandi, B.H.

Publication Name: J. Clin. Endocrin. Met.

Position of the American Dietetic Association: Health implications of dietary fiber.

Authors: Marlett, J.A., McBurney, M.I., Slavin, J.L.

Publication Name: J. Am. Dietetic Assoc.

Dietary Mono- and polyunsaturated fatty acids similarly affect LDL size in healthy men and women.

Authors: M Kratz, E G?lbah?e, A Eckardstein, P Cullen, A Gignarella, G Assmann, U Wahrburg.

Publication Name: J Nutr

Randomized Clinical Trials on the Effects of Dietary Fat and Carbohydrate on Plasma lipoproteins and cardiovascular disease.

Authors: F Sacks, M Katan.

Publication Name: Am J Med.

Effect of an Increased Intake of Alpha-Linolenic Acid and Group Nutritional Education on Cardiovascular Risk Factors: The Mediterranean Alpha-Linolenic Enriched Groningen Dietary Intervention (MARGIN) Study.

Authors: W J E Bemelmans, J Broer, E J M Feskens, A J Smit, F A J Muskiet, J D Lefrandt, V J J Bom et al.

Publication Name: Am. J.Clin. Nutr.

Conversion of alpha-linolenic acid to eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acids in young women.

Authors: G C Burge, S A Wootton.

Publication Name: Brit. J. Nutr.

Omega-3 Fatty Acids in Inflammation and Autoimmune Diseases.

Authors: Simopoulos, A.P.

Publication Name: J. Am. Coll.Nutr.

CDC Arras flax

Authors: Rowland, G.G., Hormis, Y.A., Rashid, K.Y.

Publication Name: Can. J. Plant Sci.

CDC Bethune flax.

Authors: Rowland, G.G., Hormis, Y.A., Rashid, K.Y.

Publication Name: Can. J. Plant Sci.

CDC Normandy flax.

Authors: Rowland, G.G., McHughen, A.G., Hormis, Y.A., Rashid, K.Y.

Publication Name: Can. J. Plant Sci.

CDC Valour flax.

Authors: Rowland, G.G., Hormis, Y.A., Rashid, K.Y.

Publication Name: Can. J. Plant Sci.

The major allergen of linseed.

Authors: León, F., Rodríguez, M., Cuevas, M.

Publication Name: Allergy

Estrogen Metabolism and the Diet-Cancer Connection: Rationale for Assessing the Ratio of Urinary Hydroxylated Estrogen Metabolites.

Authors: Lord, R.S., Bongiovanni, B., Bralley, J.A.

Publication Name: Altern. Med. Rev.

The effect of flaxseed supplementation in processed foods on serum fatty acids and enterolactone.

Authors: Tarpila, S., Aro, A., Salminen, I., Tarpila, A., Kleemola, P., Akkila, J., Adlercreutz, H.

Publication Name: Eur. J. Clin. Nutr.

UK Food Standards Agency a-linolenic acid workshop report

Authors: Sanderson, P., Finnegan, Y.E., Williams, C.M., Calder, P.C., Burdge, G.C., Wootton, S.A., Griffin, B.A., et al.

Publication Name: Br. J. Nutr.

Efficiency of conversion of α-linolenic acid to long chain n-3 fatty acids in man

Authors: Brenna, J.T.

Publication Name: Curr. Opin. Clin. Nutr. Metab. Care

Eicosapentaenoic and docosapentaenoic acids are the principal products of a-linolenic acid metabolism in young men

Authors: Burdge, G.C. Jones, A.E. Wootton, S.A.

Publication Name: British Journal of Nutrition

Effects of Introducing Linseed in Livestock Diet on Blood Fatty Acid Composition of Consumers of Animal Products

Authors: Weill, P Schmitt, B. Chesneau, G. .Daniel, N. Safraoub, F. Legrand, P.

Publication Name: Ann. Nutr. Metab.

2001

Effects of dietary flax seed and sunflower seed supplementation on normal canine serum polyunsaturated fatty acids and skin and hair coat condition scores

Authors: Rees, C.A., Bauer, J.A., Burkholder, W.J., Kennis, R.A., Dunbar, B.L., Bigley, K.E.

Publication Name: Vet. Dermatol.

Exposure to Flaxseed or its Purified Lignan during Suckling only or Continuously

Authors: Ward, W.E., Chen, J., Thompson, L.U.

Publication Name: J. Tox. Envir.Health A

Exposure to purified lignan from flaxseed (Linum usitatissimum) alters bone development in female rats

Authors: Ward, W.E., Yuan, Y.V., Cheung, A.M., Thompson, L.U.

Publication Name: Br. J. Nutr.

Serum Enterolactone and Risk of Breast Cancer: A Case-Control Study in Eastern Finland

Authors: Pietinen, P., Stumpf, K., M?nnist?, S., Kataja, V., Uusitupa, M., Adlercreutz, H.

Publication Name: Cancer Epid. Biomarkers & Prevention

The Association of Fatty Acids with Prostate Cancer Risk.

Authors: Newcomer, L.M., King, I.B., Wicklund, K.G. Stanford, J.L.

Publication Name: The Prostate

The fats of Life: The Role of Omega-3 Fatty Acids in the Prevention of Coronary Heart Disease

Authors: Harper, C.R., Jacobson, T.A.

Publication Name: Arch. Intern. Med.

Urinary Phytoestrogens and Postmenopausal Breast Cancer Risk.

Authors: den Tonkelaar, I., Keinan-Boker, L., Van’t Veer, P., Arts, C.J.M., Adlercreutz, H., Thijssen, J.H.H., Peeters, P.H.H.

Publication Name: Cancer Epid. Biomarkers Prev.

Flaxseed in Lupus Nephritis: A Two-Year Nonplacebo-Controlled Crossover Study

Authors: Clark, W.F., Kortas, C., Heidenheim, A.P., Garland, J., Spanner, E., Parbtani, A.

Publication Name: J. Am. Coll. Nutr.

The Mediterranean Diets: What Is So Special about the Diet of Greece? The Scientific Evidence.

Authors: Simopoulos, A.P.

Publication Name: J. Nutr.

AHA Scientific Statement: Summary of the Scientific Conference on Dietary Fatty Acids and Cardiovascular Health. Conference Summary From the Nutrition Committee of the American Heart Association.

Authors: Kris-Etherton, P., Daniels, S.R., Eckel, R.H., Engler, M., Howard, P.V., Krauss, R.M., Lichtenstein, A.H., et. al.

Publication Name: J. Nutr.

Dietary supplementation with eicosapentaenoic acid, but not with other long-chain n-3 or n-6 polyunsaturated fatty acids, decreases natural killer cell activity in healthy subjects aged >55 y.

Authors: Thies, F., Nebe-von-Caron, G., Powell, J.R., Yaqoob, P., Newsholme, E.A., Calder, P.C.

Publication Name: Am. J. Clin. Nutr.

Intake of Dietary Phytoestrogens Is Low in Postmenopausal Women in the United States: The Framingham Study.

Authors: de Kleijn, M.J.J., van der Schouw, Y.T., Wilson, P.W.F., Adlercreutz, H., Mazur, W., Grobbee, D.E., Jacques, P.F.

Publication Name: J. Nutr.

Physiological compartmental analysis of alpha-linolenic acid metabolism in adult humans.

Authors: Pawlosky, R.J., Hibbeln, J.R., Novotny, J.A., Salem, N.

Publication Name: J. Lipid Res.

Secoisolariciresinol diglucoside from flaxseed delaysthe development of type 2 diabetes in Zucker rat.

Authors: Prasad, K.

Publication Name: J. Lab. Clin. Med.

The Role of Phytoestrogens in the Prevention and Treatment of Osteoporosis in Ovarian Hormone Deficiency

Authors: Arjmandi, B.H.

Publication Name: J. Am. Coll Nutr.

The effect of replacing dietary saturated fat with polyunsaturated or mono-unsaturated fat on plasma lipids in free-living young adults.

Authors: L Hodson, C M Skeaff, W-A H Chisholm.

Publication Name: European Journal of Clinical Nutrition.

Moderate dietary fat consumption as a risk factor for ischemic heart disease in a population with a low fat intake: a case-control study in Korean men.

Authors: I Suh, K Oh, K Lee, B Psaty, C Nam, S Kim, H Kang, et al.

Publication Name: Am J Clin Nutr.

Relationship Between Dietary Linolenic Acid and Coronary Artery Disease in the National Heart, Lung, and Blood Institute Family Heart Study.

Authors: L Djousse, J S Pankow, J H Eckfeldt, A R Folsom, P N Hopkins, M A Province, Y Hong, R C Ellison.

Publication Name: Am. J. Clin. Nutr.

Pilot Study of Dietary Fat Restriction and Flaxseed Supplementation in Men with Prostate Cancer Before Surgery: Exploring the Effects on Hormonal Levels, Prostate-Specific Antigen, and Histopathologic Features

Authors: W Demark-Wahnefried, D T Price, T J Polascik, C N Robertson, E E Anderson, D F Paulson, P J Walther, M Gannon.

Publication Name: Circulation.

Biosynthetic Pathway to the Cancer Chemopreventive Secoisolariciresinol Diglucoside-Hydroxymethyl Glutaryl Ester-Linked Lignan Oligomers in Flax (Linum usitatissimum) Seed.

Authors: Ford, J.D., Huang, J-S., Wang, H-B., Davin, L.B., Lewis, N.G.

Publication Name: J. Nat. Prod.

Alterations in Brain Function After Loss of Docosahexaenoate Due to Dietary Restriction of n-3 Fatty Acids.

Authors: Salem, Jr., N., Moriguchi, T., Sheaff Greiner, R., McBride, K., Ahmad, A., Catalan, J.N., Slotnick, B.

Publication Name: J. Mol. Neuroscience

Can Manipulation of the Ratios of Essential Fatty Acids Slow the Rapid Rate of Postmenopausal Bone Loss?

Authors: Kettler, D.B.

Publication Name: Altern Med Rev

Small intestinal digestibility of microbial and endogenous amino acids in dairy cows

Authors: Larsen, M., Madsen, T.G. Weisbjerg, M.R., Hvelplund, T., Madsen, J.

Publication Name: J. Anim. Physiol. a. Anim. Nutr.

Letter to the Editor: Correspondence re: A. M. Hutchins et al., Flaxseed Influences Urinary Lignan Excretion in a Dose-dependent Manner in Post-menopausal Women. Cancer Epidemiol. Biomark. Prev., 9: 1113?1118, 2000

Authors: Tsakok. A.D.

Publication Name: Cancer Epidemiology, Biomarkers & Prevention

Exposure to Flaxseed and its Purified Lignan Reduces Bone Strength in Young but Not Older Male Rats

Authors: Ward, W.E., Yuan, Y.V., Cheung, A.M., Thompson, L.U.

Publication Name: J. Toxicology & Environmental Health, Part A,

Letter to the Editor: Additional Data on the Storage Stability

Authors: Pryzbylski, R. Daun, J.K.

Publication Name: JAOCS

Physiological compartmental analysis of alpha-linolenic acid metabolism in adult humans

Authors: Pawlosky, R.J. Hibbeln, J.R. Novotny, J.A. Salem, Jr., N.

Publication Name: Journal of Lipid Research

Types of Dietary Fat and Risk of Coronary Heart Disease: A Critical Review

Authors: Hu, F.B. Manson, J.E. Willett, W.C.

Publication Name: Journal of the American College of Nutrition

Alpha-Linolenic acid intake is not beneficially associated with 10-y risk of coronary artery disease incidence: the Zutphen Elderly Study1�3

Authors: Oomen, C.M. Ock�, M.C. Feskens, E.J.M. Kok, F.J. Kromhout, D.

Publication Name: Am. J. Clin. Nutr.

Cholesterol lowering benefits of soy and linseed enriched foods

Authors: Ridges, L. Sunderland, R. Moerman, K. Meyer, B. Astheimer, L. Howe, P.

Publication Name: Asia Pacific J. Clin. Nutr.

Flaxseed as a functional food source

Authors: Oomah, B.D.

Publication Name: J Sci Food Agri

2000

Quantitation of the Lignan Secoisolariciresinol Diglucoside in Baked Goods Containing Flax Seed or Flax Meal

Authors: Muir, A.D., Westcott, N.D.

Publication Name: J. Agric. Food Chem.

A novel treatment for lupus nephritis: lignan precursor derived from flax

Authors: Clark, W.F., Muir, A.D., Westcott, N.D., Parbtani, A.

Publication Name: Lupus

Nutritional and hematological impact of dietary flaxseed and defatted flaxseed meal in rats

Authors: Babu, U.S., Mitchell, G.V., Wiesenfeld, P., Jenkins, M.Y., Gowda, H.

Publication Name: Int. J. Food Sci. Nutr.

Flaxseed Influences Urinary Lignan Excretion in a Dose-dependent Manner in Postmenopausal Women

Authors: Hutchins, A.M., Martini, M.C., Olson, B.A., Thomas, W., T Slavin, J.L.

Publication Name: Cancer Epid. Biomarkers & Prev.

The Effect of Flaxseed and Wheat Bran Consumption on Urinary Estrogen Metabolites in Premenopausal Women

Authors: Haggans, C.J., Travelli, E.J., Thomas, W., Martini, M.C., Slavin, J.L.

Publication Name: Cancer Epid. Biomarkers & Prev.

Plasma insulin-like growth factor I levels in rats are reduced by dietary supplementation of flaxseed or its lignan secoisolariciresinol diglycoside

Authors: Rickard, S.E., Yuan, Y.V., Thompson, L.U.

Publication Name: Cancer Letters

Urinary Composition and Postprandial Blood Changes in 3H-Secoisolariciresinol Diglycoside (SDG) Metabolites in Rats Do Not Differ between Acute and Chronic SDG Treatments

Authors: Rickard, S.E., Thompson, L.U.

Publication Name: J. Nutr.

Exposure to Flaxseed or Purified Lignan During Lactation Influences Rat Mammary Gland Structures

Authors: Ward, W.E., Jiang, F.O., Thompson, L.U.

Publication Name: Nutr. Cancer

Low alpha-linolenic acid content of adipose breast tissue is associated with an increased risk of breast cancer

Authors: Klein, V., Chaj?s, V., Germain, E., Schulgen, G., Pinault, M., Malvy, D., Lefrancq, T., et al.

Publication Name: Eur. J. Cancer

a-Linolenic Acid and Risk of Prostate Cancer: A Case-Control Study in Uruguay.

Authors: De St?fani, E., Deneo-Pellegrini, H., Boffetta, P., Ronco, A., Mendilaharsu, M.

Publication Name: Cancer Epid. Biomarkers Prev.

Protective effect of secoisolariciresinol diglucoside against streptozotocin-induced diabetes and its

Authors: Prasad, K., Mantha, S.V., Muir, A.D., Westcott, N.D.

Publication Name: Mol. Cell. Biochem.

Polyunsaturated fatty acids in the food chain in the United States.

Authors: Kris-Etherton, P.M., Taylor, D.S., Yu-Poth, S., Huth, P., Moriarty, K., Fishell, V., Hargrove, R.L., et. al.

Publication Name: Am. J. Clin. Nutr.

Oxidative stress as a mechanism of diabetes in diabetic BB prone rats: Effect of secoisolariciresinol diglucoside (SDG).

Authors: Prasad, K.

Publication Name: Molecular & Cellular Biochemistry.

AHA Dietary guidelines Revision 2000: A statement for healthcare professionals from the nutrition committee of the American Heart Association.

Authors: R Krauss, R Eckel, B Howard, L Appel, S Daniels, R Deckelbaum, J Erdman, et al.

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Importance of n-3 Fatty Acids in Health and Disease.

Authors: W Connor.

Publication Name: Am. J. Clin. Nutr.

The conditional nature of the dietary need for polyunsaturates: a proposal to reclassify “essential fatty acids” as “conditionally indispensable” or “conditionally-despensable” fatty acids.

Authors: S C Cunnane.

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Epidemiological and Clinical Trial Evidence for the Relationship Between Type of Fat and CVD Risk. Dietary Fatty Acids & Cardiovascular Health.

Authors: F Sacks.

Publication Name: Meeting of the American Heart Association. June 5-6, 2000. Reston, Virginia.

Fatty Acid Modulation of Endothelial Activation.

Authors: R De Caterina, J Liao, P Libby.

Publication Name: Am. J. Clin. Nutr.

Cardiovascular Disease: A Historical Perspective.

Authors: D Smith.

Publication Name: Jpn. J. Vet. Res.

Essential Fatty Acids in Infant Nutrition: Lessons and Limitations from Animal Studies in Relation to Studies on Infant Fatty Acid Requirements.

Authors: S Innis.

Publication Name: Am. J. Clin. Nutr.

HPLC Method for Analysis of Secoisolariciresinol Diglucoside in Flaxseeds.

Authors: Johnsson, P., Kamal-Eldin, A., Lundgren, L.N., Aman, P.

Publication Name: J. Agric. Food Chem.

Testing the potential of flaxseed to affect spermatogenesis: morphometry.

Authors: Sprando, R.L., Collins, T.F.X., Wiesenfeld, P., Babu, U.S., Rees, C., Black, T., Olejnik, N., Rorie, J.

Publication Name: Food Chem. Toxicol.

The Effect of Maternal Exposure to Flaxseed on Spermatogenesis in F1 Generation Rats.

Authors: Sprando, R.L., Collins, T.F.X., Black, T.N., Olejnik, N., Rorie, J.I., Scott, M., Wiesenfeld, P., et.al.

Publication Name: Food Chem. Toxicol.

Antioxidant factors in plant foods and selected oilseeds.

Authors: Shahidi, F.

Publication Name: BioFactors

Effect of Low-to-Moderate Amounts of Dietary Fish Oil on Neutrophil Lipid Composition and Function

Authors: Healy, D.A., Wallace, F.A., Miles, E.A., Calder, P.C., Newsholme, P.

Publication Name: Lipids

Polyunsaturated fatty acids are potent neuroprotectors

Authors: Lauritzen, I., Blondeau, N., Heurteaux, C., Widmann, C., Romey, G., Lazdunski, M.

Publication Name: The EMBO Journal

Compartmental modeling with nitrogen-15 to determine effects of degree of fat saturation on intraruminal N recycling

Authors: Oldick, B.S., Firkins, J.L., Kohn, R.A.

Publication Name: J. Anim. Sci.

Reproductive management of postpartum cows

Authors: Roche, J.F., Mackey, D., Dsikin, M.D.

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Effects of Dietary α-Linolenic Acid on the Conversion and Oxidation of 13C-α-Linolenic Acid

Authors: Vermunt, S.H.F., Mensink, R.P., Simonis, M.M.G., Hornstra, G.

Publication Name: Lipids

Storage Stability of Milled Flaxseed

Authors: Malcolmson, L.J. Pryzbylski, R. Daun, J.K.

Publication Name: JAOCS

Dietary fat intake and prostate cancer risk: a case control study in Spain.

Authors: Ramon, J.M. Bou, R. Romea, S. Alkiza, M.E. Jacas, M.

Publication Name: Cancer Causes & Control

Flaxseed: A Source of Hypocholesterolemic and Antiatherogenic Agents

Authors: Prasad, K.

Publication Name: Drug News & Perspectives

1999

Dietary supplementation with secoisolariciresinol diglycoside (SDG) reduces experimental metastasis of melanoma cells in mice

Authors: Li, D., Yee, J.A., Thompson, L.U., Yan, L.

Publication Name: Cancer Letters

Dose Effects of Flaxseed and Its Lignan on N-Methyl-N-Nitrosourea-Induced Mammary Tumorigenesis in Rats

Authors: Rickard, S.E., Yuan, Y.V., Chen, J., Thompson, L.U.

Publication Name: Nutr. Cancer

Flaxseed and Lignans Increase Cecal b-Glucuronidase Activity in Rats

Authors: Jenab, M., Rickard, S.E., Orcheson, L.J., Thompson, L.U.

Publication Name: Nutr. Cancer

Omega-3 Fatty Acids in Adipose Tissue and Risk of Myocardial Infarction. The EURAMIC Study.

Authors: Guallar, E., Aro, A., Jim?nez, F.J., Martın-Moreno, J.M., Salminen, I., van’t Veer, P., Kardinaal, A.F.M. et. al.

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Essential fatty acids and cardiovascular disease: the Edinburgh Artery Study

Authors: Leng, G.S., G.C., Taylor, Lee, A.J., Fowkes, F.G.R., Horrobina, D.

Publication Name: Vascular Med.

Prevention of Sudden Cardiac Death by Dietary Pure ω-3 Polyunsaturated Fatty Acids in Dogs

Authors: Billman, G.E., Kang, J.X., Leaf, A.

Publication Name: Circulation

Effect of Flaxseed Consumption on Urinary Estrogen Metabolites in Postmenopausal Women

Authors: Haggans, C.J., Hutchins, A.M., Olson, B.A., Thomas, W., Martini, M.C., Slavin, J.L.

Publication Name: Nutrition & Cancer

Reduction of Serum Cholesterol and Hypercholesterolemic Atherosclerosis in Rabbits by Secoisolariciresinol Diglucoside Isolated From Flaxseed.

Authors: Prasad, K.

Publication Name: Circulation

Exposure to flaxseed or its lignan component during different developmental stages influences rat mammary gland structure.

Authors: Tou, J.C.L., Thompson, L.U.

Publication Name: Carcinogenesis

Human metabolism of mammalian lignan precursors in raw and processed flaxseed.

Authors: Nesbitt, P.D., Lam, Y., Thompson, L.U.

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Alpha-Linolenic acid in health and disease.

Authors: Connor, W.E.

Publication Name: Am. J. Clin. Nutr.

Antioxidant activity of the flaxseed lignan secoisolariciresinol diglycoside and its mammalian lignan metabolites enterodiol and enterolactone.

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Publication Name: Molecular & Cellular Biochemistry.

Health aspects of partially defatted flaxseed, including effects on serum lipids, oxidative measures, and ex vivo androgen and progestin activity: a controlled crossover trial.

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Essential fatty acids in health and chronic disease.

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Mediterranean Diet, Traditional risk factors, and the rate of cardiovascular complications after myocardial infarction.

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Comparison of the effects of two low fat diets with different alpha-linolenic: linoleic acid ratios on coagulation and fibrinolysis.

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Mediterranean Diet, Traditional Risk Factors, and the Rate of Cardiovascular Complications After Myocardial Infarction – Final Report of the Lyon Diet Heart Study.

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Editorial: Dietary Prevention of Coronary Heart Disease – The Lyon Diet Heart Study.

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Dietary Intake of a-linolenic Acid and Risk of Fatal Ischemic Heart Disease Among Women.

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Effect of dietary alpha-linolenic acid on thrombotic risk factors in vegetarian men.

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Replacing Saturated Fat with PUFA-Rich (Sunflower Oil) or MUFA-Rich (Rapeseed, Olive and High-Oleic Sunflower Oil) Fats Resulted in Comparable Hypocholesterolemic Effects in Cholesterol-Fed Hamsters.

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Novel metabolites of the mammalian lignans enterolactone and enterodiol in human urine.

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Isolation and Characterization of the Lignans, Isolariciresinol and Pinoresinol, in Flaxseed Meal.

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Dose, Timing, and Duration of Flaxseed Exposure Affetct Reproductive Indices and Sex Hormone Levels in Rats.

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Effect of Dietary Docosahexaenoic Acid on Desaturation and Uptake in vivo of Isotope-Labeled Oleic, Linoleic, and Linolenic Acids by Male Subjects

Authors: Emken, E.A., Adlof, R.O., Duval, S.M., Nelson, G.J.

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Flaxseed ameliorates interstitial nephritis in rat polycystic kidney disease

Authors: Ogborn, M.R. Nitschmann, E. Weiler, H. Leswick, D. Bankovic-Calic, N.

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Association of Energy and Fat Intake with Prostate Carcinoma Risk.

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Effect of dietary alpha-linolenic acid on thrombotic risk factors in vegetarian men

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Effects of dietary n-3 polyunsaturated fatty acids from plant and marine origin on platelet aggregation in healthy elderly subjects

Authors: Wensing, A.G.C.L. Mensink, R.P. Hornstra, G.

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1998

Dietary flaxseed supplementation and experimental metastasis of melanoma cells in mice

Authors: Yan, L. Yee, J.A., Li, D., McGuire, M.H., Thompson, L.U.

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Health aspects of fish and n-3 polyunsaturated fatty acids from plant and marine origin.

Authors: de Deckere, E.A.M., Korver, O., Verschuren, P.M., Katan, M.B.

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Flaxseed and Its Lignan Precursor, Secoisolariciresinol Diglycoside, Affect Pregnancy Outcome and Reproductive Development in Rats.

Authors: Tou, J.C.L., Chen, J., Thompson, L.U.

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Whole Flaxseed Consumption Lowers Serum LDL – Cholestoral and Lipoprotein(a) Concentrations in Postmenopausal Women.

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Inhibitors of pepsin, trypsin and chymotrypsin in seeds of plants consumed by humans and animals. I. Evaluation of pepsin, trypsin, and chymotrypsin inhibitors activity in seeds of 26 plant species.

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Oil Blends containing hydrogenated or interesterified fats: differential effects on plasma lipids.

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Replacement of Linoleic Acid with Alpha-Linolenic Acid does not Alter Blood Lipids in Normolipidaemic Men.

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Can adults adequately convert alpha-linolenic acid (18:3n-3) to eicosapentaenoic acid (20:5n-3) and docosahexaenoic acid (22:6n-3)?

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Process-induced compositional changes of flaxseed.

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In Vitro Biohydrogenation and Total Tract Digestibility of Oleamide by Sheep

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Dietary polyunsaturated fatty acids decrease anti-dsDNA and anti-cardiolipin antibodies production in idiotype induced mouse model of systemic lupus erythematosus

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CLINICAL REVIEW 97: Potential Health Benefits of Dietary Phytoestrogens: A Review of the Clinical, Epidemiological, and Mechanistic Evidence

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Experimental studies on lignans and cancer

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Dietary Phytoestrogens

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Effect of Dietary Flaxseed on Fatty Acid Composition, Superoxide, Nitric Oxide Generation and Ntilisterial Activity of Peritoneal Macrophages from Female Sprague-Dawley Rats

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Lignans in homemade and commercial products containing flaxseed.

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Dietary fat intake and the risk of coronary heart disease in women.

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Randomized , Double-Blind, Placebo-Controlled Trial of Fish Oil & Mustard Oil in Patients with suspected Acute Myocardial Infarction: The Indian Experiment of Infarct Survival – 4.

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Arterial compliance in obese subjects is improved with dietary plant n-3 fatty acid from flaxseed oil despite increased LDL oxidizability.

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Flaxseed improves arterial compliance.

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Dietary Flaxseed in Prevention of Hypercholesterolemic Atherosclerosis.

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It is More Important to Increase the Intake of Unsaturated Fats than to Decrease the Intake of Saturated Fats: Evidence from Clinical Trials Relating to Ischemic Heart Disease.

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Alpha-Linolenic Acid and Marine Long-Chain n-3 Fatty Acids Differ Only Slightly in their Effects on Hemostatic Factors in Healthy Subjects.

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Polyunsaturated fatty acids: Signaling agents for intestinal cancer?

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Phyto-oestrogens and Western diseases.

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Hydroxyl Radical-Scavenging Property of Secoisolariciresinol Diglucoside (SDG) Isolated from Flaxseed.

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Case-Control Study of Phyto-Oestrogens and Breast Cancer.

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Phytochemicals: Guardians of our health.

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Health effects of flaxseed mucilage, lignans.

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Phytoestrogens and lignans: Effects on reproduction and chronic diseases.

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Variability in Anticancer Lignan Levels in Flaxseed.

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Breast Cancer: Aetiological Factors and Associations (A Possible Protective Role of Phytoestrogens)

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Phytoestrogen Concentration Determines Effects on DNA Synthesis in Human Breast Cancer Cells.

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Effects of preterm infant formula supplementation with a-linolenic acid with a linoleate/a-linolenate ratio of 6:1: a multicenter study.

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CDC Triffid transgenic flax.

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0ral administration of unsaturated fatty acids : effects on human peripheral blood T lymphocyte proliferation.

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Kinetics of the incorporation of dietary fatty acids into serum cholesteryl esters, erythrocyte membranes, and adipose tissue: an 18-month controlled study

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Intake of Fatty Acids and Risk of Coronary Heart Disease in a Cohort of Finnish Men: The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study

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Prediagnostic level of fatty acids in serum phospholipids: n-3 and n-6 fatty acids and the risk of prostate cancer

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Prevention of Cardiac Arrhythmia by Dietary (n-3) Polyunsaturated Fatty Acids and Their Mechanism of Action 1,2

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Hydroxyl radical-scavenging property of secoisolariciresinol diglucoside (SDG) isolated from flax-seed

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Biomarkers of Essential Fatty Acid Consumption and Risk of Prostatic Carcinoma.

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Chemical Changes in the Lipids of Canola and Flax Seeds During Storage.

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Normal Subjects Consuming Physiological Levels of 18:3(n-3) and 20:5(n-3) from Flaxseed or Fish Oils

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Protective effects of free polyunsaturated fatty acids on arrhythmias induced by lysophosphatidylcholine or palmitoylcarnitine in neonatal rat cardiac myocytes

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Dietary fat & risk of coronary heart disease in men: cohort follow up study in the United States.

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Linolenic acid in rapeseed oil partly compensates for the effect of fish restriction on plasma long chain n-3 fatty acids.

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The Canadian Society for Nutritional Sciences 1995 Young Scientist Award Lecture: Recent Studies on the Synthesis, Beta oxidation, and Deficiency of Linoleate and Alpha-linolenate: Are Essential Fatty Acids more Aptly Named Indispensable or Conditionally

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What’s the new soy on the block?: Looks like flax.

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Blood and Aorta Lipid Status and Platelet Function in Swine Modified by Dietary Alpha -Linolenic Acid-Rich Flaxseed.

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Metabolism of linoleic and alpha linolenic acids in cultured cardiomyocytes: effect of different n-6 and n-3 fatty acid supplementation.

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Antithromboxane activity of dietary alpha linolenic acid: A pilot study.

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The relationship between dietary alpha-linolenic:linoleic acid and rat eicosapentaenoic and arachidonic acids.

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Flaxseed and its Lignan and Oil Components Reduce Mammary Tumor Growth at a Late Stage of Carcinogenesis

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The effect on human tumor necrosis factor alpha and interleukin 1-beta production of diets enriched in n-3 fatty acids from vegetable oil or fish oil.

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The Effect of Alpha-Linolenic Acid-Rich Emulsion on Fatty Acid Metabolism and Leukotriene Generation of the Colon in a Rat Model with Inflammatory Bowel Disease.

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The Nutritional Effect of Alpha-Linolenic Acid-Rich Emulsion with Total Parenteral Nutrition in a Rat Model with Inflammatory Bowel Disease

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The ratio of n-6 to n-3 polyunsaturated fatty acids in the rat diet alters serum lipid levels and lymphocyte function

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x-linolenic acid dietary deficiency alters age-related changes of dopaminergic and serotoninergic neurotransmission in the rat frontal cortex.

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High-Fat Diet-Induced Hyperglycemia and Obesity in Mice: Differential Effects of Dietary Oils.

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Phytoestrogens: Friend or foe?

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A Review of the Clinical Effects of Phytoestrogens.

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The Influence of Flaxseed and Lignans on Colon Carcinogenesis and B-Glucuronidase Activity.

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Dose-Dependent Production of Mammalian Lignans in Rats and In Vitro from the Purified Precursor Secoisolariciresinol Diglycoside in Flaxseed.

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Antitumorigenic Effect of a Mammalian Lignan Precursor from Flaxseed.

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Dietary Linolenic Acid-Method Increase in Vascular Prostacyclin Formation.

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Effect of dietary alpha linolenic acid deficiency on habituation.

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Effect of Rumen Protozoa on Nitrogen Utilization by Ruminants

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DIVISION S-4-SOIL FERTILITY & PLANT NUTRITION Accumulation of Sodium and Potassium by Flax

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Energy, Nutrient Intake & Prostate Cancer Risk: A Population Based Case-Control Study In Sweden.

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Dietary fat and risk of coronary heart disease in men: cohort follow up study in the United States

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Dietary Canola Oil Modifies Myocardial Fatty Acids and Inhibits Cardiac Arrhythmias in Rats

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Alpha-linolenic acid in the treatment of rheumatoid arthritis. A double.blind, placebo-controlled and randomized study: flaxseed vs. safflower seed.

Authors: Nordstr?m, D.C.E., Honkanen, V.E.A., Nasu, Y., Antila, E., Friman, C., Konttinen, Y.T.

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Differences exist in the relationships between dietary linoleic and a-linolenic acids and their respective

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Cretan Mediterranean diet for prevention of coronary heart disease.

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Monounsaturated versus polyunsaturated dietary fat and serum lipids.

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Effects of dietary alpha- and gamma-linolenic acids on liver fatty acids, lipid metabolism and survival in sepsis.

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Alpha-linolenic Acid- and Docosahexaenoic Acid-Enriched Eggs from Hens Fed Flaxseed: Influence on Blood Lipids and Platelet Phospholipid Fatty Acids in Humans.

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The effect of dietary alpha-linolenic acid on blood lipids and lipoproteins in humans.

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Serum fatty acids and the risk of stroke.

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Supplementation with flaxseed oil versus sunflowerseed oil in healthy young men consuming a low fat diet: Effects on platelet composition and function.

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Dietary Alpha-Linoleic Acid Alters the Fatty Acid Composition of Lipid Classes in Swine Tissues.

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Flaxseed Oil and cancer: alpha-linolenic acid and carcinogenesis. In: Flaxseed in Human Nutrition.

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Free radical-dependent suppression of growth of mouse myeloma cells by alpha linolenic acid and eicosapentaenoic acids in vitro.

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Flaxseed: A Potential Treatment for Lupus Nephritis.

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Effects of Flaxseed and Flax Oil Diets in a Rat-5/6 Renal Ablation Model.

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Immunomodulatory effects of Flaxseed and Other Oils rich in Alpha-linolenic acid. In: Flaxseed in Human Nutrition.

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Flaxseed and its Components in Renal Disease. In: Flaxseed in Human Nutrition.

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The Effect of Different N-6/n-3 Essential Fatty Acid Ratios on Calcium Balance and Bone in Rats.

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Effects of Dietary Alpha-Linolenic Acid Deficiency on Neuromuscular and Cognitive Functions in Mice.

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Synthesis of linoleate and alpha-linolenate by chain elongation in the rats.

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Antimalarial effects of Flaxseed and Flaxseed Oil.

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Diet-induced thermogenesis is lower in rats fed a lard diet than in those fed a high oleic acid safflower oil diet, a safflower oil diet or a linseed oil diet.

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Functional properties, uses of flaxseed protein.

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Fecal Lignan and Isoflavonoid Excretion in Premenopausal Women Consuming Flaxseed Powder.

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Effect of Dietary Linseed Oil on Tumoricidal Activity and Eicosanoid Production in Murine Macrophages.

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Changes in risk factors explain changes in mortality from ischaemic heart disease in Finland

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Levels of Polyunsaturated Fatty Acids in Tissues from Zinc-Deficient Rats Fed a Linseed Oil Diet.

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Dietary linoleic acid influences desaturation and acylation of deuterium-labeled linoleic and linolenic acids

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Comparison of the effects of two diets rich in monounsaturated fatty acids differing in their linolenic/alpha-linolenic acid ratio on platelet aggregation.

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Nutritional Attributes of Traditional Flaxseed in Healthy Young Adults.

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Authors: M de Lorgeril, S Renaud, N Mamelle, P Salen, J L Martin, I Monjaud, J Guidollet, et al.

Publication Name: The Lancet.

Effect of oleic, linoleic, gamma?linolenic and alpha?linolenic acids on VLDL?TG and cholesterol synthesis in rat primary cultured hepatocytes.

Authors: Y Fujiyama-Fujiwara, O Igarashi.

Publication Name: Pathophys.

Dietary Substitution with an a-Linolenic Acid—Rich Vegetable Oil Increases Eicosapentaenoic Acid Concentrations in Tissues.

Authors: E Mantzioris, M J James, R A Gibson, L G Cleland.

Publication Name: Amer. J. Clin. Nutr.

Lipid Peroxides and Essential Fatty Acids in Patients with Coronary Heart Disease.

Authors: K Vijay Kumar, U N Das.

Publication Name: J. Nutr. Med.

Physicochemical perturbation of x-linolenic acid related to cell proliferation

Authors: H Fukui, T Sato, J Sunamoto.

Publication Name: Bull. Chem. Soc. Jpn.

Omega 3 Fatty acid supplementation in clinical and experimental lupus nephritis. Proceedings from the National Kidney Foundation Annual Meeting.

Authors: W F Harris, A Parbtani.

Publication Name: Amer. J. Kidney Dis.

Chronic Dietary Alpha-Linoleic Acid Deficiency Alters Dopaminergic and Serotoninergic Neurotransmission in Rats.

Authors: S Delion, S Chalon, J Herault, D Guilloteau, J C Besnard, G Durand.

Publication Name: J. Nutr.

The effects of dietary oils on the fatty acid composition and osmotic fragility of rat erythrocytes.

Authors: M Kirchgebner, G I Stangl, A M Reichlmayr-Lais, K Elder.

Publication Name: Z. Emahrungswiss.

Urinary Lignan and Isoflavonoid Excretion in Premenopausal Women Consuming Flaxseed Powder.

Authors: J W Lampe, M C Martini, M S Kurzer, H Adlercreutz, J L Slavin.

Publication Name: Am. J. Clin. Nutr.

Regulation of Lipid Metabolism in the Rumen

Authors: Jenkins, T.C.

Publication Name: J. Nutr.

Prospective Study of Plasma Fatty Acids and Risk of Prostate Cancer

Authors: Gann, P.H. Hennekens, C.H. Sacks, F.G. Giovannucci, E.L. Stampfer, M.J.

Publication Name: J. Natl. Canc. Inst.

1993

Abrogation of MRL/lpr lupus nephritis by dietary flaxseed

Authors: Hall, A.V., Parbtani A., Clark W.F., Spanner E., Keeney M., Chin-Yee I., Philbrick D.J., Holub B.J.

Publication Name: Am J Kidney Dis

Cardiac Arrhythmia in Rats in Response to dietary N-3 Fatty Acids from Red Meat, Fish Oil and Canola Oil

Authors: Siebert, B.D., McLennan, P. L., Woodhouse, J.A., Charnock, J. S.

Publication Name: Nutr. Res.

Effect of Dietary alpha-Linolenic Acid and Its Ratio to Linoleic Acid on Platelet and Plasma Fatty Acids and Thrombogenesis.

Authors: Chan, J.A., McDonald, B.E., Gerrard, J.M., Bruce, V.M., Weaver, B.J., Holub, B.J.

Publication Name: Lipids

Reducing Atherogenic Risk in hyperlipidemic humans with flaxseed supplementation: A preliminary report.

Authors: M L Bierenbaum, R Reichstein, T R Watkins.

Publication Name: Amer. J. Coll. Nutr.

High a-Linolenic Acid Flaxseed (Linum Usitatissimum): Some Nutritional Properties in Humans.

Authors: S C Cunnane, S Ganguli, C Menard, A C Liede, M J Hamadeh, Z Y Chen, T W S Wolever, D J A Jenkins.

Publication Name: Brit. J. Nutr.

Dietary a-Linolenic Acid Alters Tissue Fatty Acid Composition, But Not Blood Lipids, Lipoproteins or Coagulation Status in Humans.

Authors: D S Kelley, G J Nelson, J E Love, L B Branch, P C Taylor, P C Schmidt, B E Mackey, J M Iacono.

Publication Name: Lipids.

Essential Fatty Acid Requirements in Human Nutrition.

Authors: S M Innis.

Publication Name: Can. J. Phys. Pharma.

Assays for potentially anticarcinogenic phytoehemicals in flaxseed.

Authors: R K Harris, W J Haggerty.

Publication Name: Cereal Foods World

Effect of Flax Seed Ingestion on the Menstrual Cycle.

Authors: Phipps, W.R., Martini, M.C., Lampe, J.W., Slavin, J.L., Kurzer, M.S.

Publication Name: J. Clin. Endocrinol. Metab.

Flaxseed proteins – a review

Authors: Oomah, B.D., Mazza, G.

Publication Name: Food Chem.

A Prospective Study of Dietary Fat & Risk of Prostate Cancer

Authors: Giovannucci, E. Rimm, E.B. Colditz, G.A. Stampfer, M.J. Ascherio, A. Chute, C.C. Willett, W.C.

Publication Name: J. Natl. Canc. Inst

1992

Flaxseed supplementation and early markers of colon carcinogenesis

Authors: Serraino, M., Thompson, L.U.

Publication Name: Cancer Letters

The effect of flaxseed supplementation on the initiation and promotional stages of mammary tumorigenesis

Authors: Serraino, M., Thompson, L.U.

Publication Name: Nutr. Cancer

Epidemiological evidence of relationships between dietary polyunsaturated fatty acids & mortality in the multiple risk factor intervention trial.

Authors: T A Dolecek.

Publication Name: P.S.E.B.M.

Changes in Serum Lipids and Platelet Fatty Acid Composition Following Consumption of Eggs Enriched in Alpha-Linolenic Acid.

Authors: L K Ferrier, L Caston, S Lesson, E J Squires, B Celi, L Thomas, B J Holub.

Publication Name: Food Res. Inter.

Chemical and Nutritional Studies of Flaxseed (Variety Linott) in Rats.

Authors: W M N Ratnayake, W A Behrens, P W F Fischer, M R L’Abbe, R Mongeau, J L Beare-Rogers.

Publication Name: J. Nutr. Biochem.

Cancer preventive foods and ingredients.

Authors: A B Carafay.

Publication Name: Food Tech.

Effects of Dietary n-3 Fatty Acid-Enriched Chicken Eggs on Plasma and Tissue Cholesterol and Fatty Acid Composition of Rats.

Authors: Jiang, Z., Sire, J.S.

Publication Name: Lipids

Effects of Various Dietary Fats on Cardiolipin Acyl Composition During Ontogeny of Mice

Authors: Berger, A. Gershwin, M.E. German, J.B.

Publication Name: Lipids

Antioxidants in the prevention of human atherosclerosis. Summary of the proceedings of a National Heart, Lung, and Blood Institute Workshop: September 5-6, 1991, Bethesda, Maryland

Authors: Steinberg, D.

Publication Name: Circulation

1991

Dietary Alpha-linolenic acid is as effective as oleic acid and linolenic acid in lowering blood cholesterol in normolipidemic men.

Authors: J K Chan, V M Bruce, B E McDonald.

Publication Name: Am J Clin Nutr.

1990

Accumulation of Eicosapentaenoic Acid in Plasma Phospholipids of Subjects Fed Canola Oil.

Authors: Corner, E.J., Bruce, V.M., McDonald, B.E.

Publication Name: Lipids

Effect of fish oil on lipoproteins, lecithin:cholesterol acyltransferase, and lipid transfer protein activity in humans

Authors: Abbey, M., Clifton, P., Kestin, M., Belling, B., Nestel, P.

Publication Name: Arterioscler. Thromb. Vasc. Biol.

n-3 Fatty acids of marine origin lower systolic blood pressure and triglycerides but raise LDL cholesterol compared with n-3 and n-6 fatty acids from plants.

Authors: Kestin, M., Clifton, P., Belling, G.B., Nestel, P.J.

Publication Name: Am. J. Clin. Nutr.

1989

Influence of n-3 fatty acids on blood lipids in normal subjects.

Authors: T A B Sanders, A Hinds, C C Pereira.

Publication Name: J. Int. Med.

Functional Properties of Flax Seed Mucilage

Authors: Mazza, G., Biliaderis, C.G.

Publication Name: J. Food Sci.

1988

Preparation and Functional Properties of Linseed Protein Products Containing Differing Levels of Mucilage

Authors: Dev, D.K., Quensel, E.

Publication Name: J. Food Sci.

1987

Apha-linolenic acid deficiency in patients on long-term gastric-tube feeding: estimation of linolenic acid and long-chain unsaturated n-3 fatty acid requirement in man.

Authors: Bjerve, K.S., Mostad, I.L., Thoresen, L.

Publication Name: Am. J. Clin. Nutr.

Aipha-linolenic acid deficiency in man: effect of ethyl linolenate on plasma and erythrocyte fatty acid composition and biosynthesis of prostanoids.

Authors: Bjerve, K.S., Fischer, S., Alme, K.

Publication Name: Am. J. Clin. Nutr.

Characterization of the Seed and Leaf Lipids of High and Low Linolenic Acid Flax Genotypes

Authors: Tonnet, M.L., Green, A.G.

Publication Name: Arc.Biiochem.& Biophys.

1986

Influence of long-term diet modification on platelet function and composition in Moselle farmers.

Authors: Renaud, S., Godsey, F., Dumont, E., Thevenon, C., Ortchanian, E., Martin, J.L.

Publication Name: Am. J. Clin. Nutr.

Nutrients, Platelet Function and Composition in Nine Groups of French and British Farmers.

Authors: Renaud, S., Morazain, R., Godsey, R., Dumont, E., Thevenon, C., Martin, J.L., Mendy, F.

Publication Name: Atherosclerosis

1985

Alpha-Linolenic acid as a regulator of the metabolism of arachidonic acid: dietary implications of the ratio, n-6:n-3 fatty acids.

Authors: Budowski, P., Crawford, M.A.

Publication Name: Proceedings of the Nutrition Society

1984

Effect of Linseed Oil Ingestion on Plasma Lipid Fatty Acid Composition and Platelet Aggregability in Healthy Volunteers.

Authors: Budowski, P., Trostler, N., Lupo, M., Vaisman, N., Eldor, A.

Publication Name: Nutr. Res.

1983

The Influence of Different Types of n-3 Polyunsaturated Fatty Acids on Blood Lipids and Platelet Function in Healthy Volunteers.

Authors: T A B Sanders, F Roshanai.

Publication Name: Clin. Sci.

1980

Isolation of Factors in Linseed Oil Meal Protective against Chronic Selenosis in Rats

Authors: Palmer, I.S., El Olson, O., Halverson, A.W., Miller, R., Smith, C.

Publication Name: J. Nutr.

1975

Association Between a Low Adipose Tissue Content of Polyunsaturated Fatty Acids and Both Glucose Intolerance and Hypertriglyceridemia in Apparently Healthy Men.

Authors: L A Carlson, G Walldius.

Publication Name: Acta Med. Scand.

1970

The Oslo Diet-Heart Study.

Authors: P Leren.

Publication Name: Circulation.

1966

A Quantitative Assessment of the Contribution of Individual Plasma Amino Acids to the Synthesis of Milk Proteins by the Goat Mammary Gland

Authors: Mepham, T.B., Linzell, J.L.

Publication Name: Biochem. J.

1964

Linolenic Acid for the Prevention of Thrombosis and Myocardial Infarction.

Authors: Owren, P.A., Hellem, A.J., ?degaard, A.

Publication Name: the Lancet

1957

Prediction of serum-cholesterol responses of man to changes in fats in the diet.

Authors: A Keys, J Anderson, F Grande.

Publication Name: The Lancet.

Essential fatty acids, degree of unsaturation, and effect of corn (maize) oil on the serum-cholesterol level in man .

Authors: A Keys, J Anderson, F Grande.

Publication Name: The Lancet.

Affiliated Organizations

Growing Flax

Human Health and Nutrition Data